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Ultrahigh-dose-rate medical proton synchrotron

A synchrotron and dose rate technology, which is applied in the field of tumor treatment, can solve the problems that the dose rate cannot be increased to the extent required by flash therapy, the instantaneous and average dose rate is low, and the cycle is long.

Pending Publication Date: 2021-09-10
SHANGHAI ADVANCED RES INST CHINESE ACADEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the structural limitation of the synchrotron makes its cycle period long, the instantaneous and average dose rate is low, and the dose rate cannot be increased to the extent required by flash therapy

Method used

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  • Ultrahigh-dose-rate medical proton synchrotron
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  • Ultrahigh-dose-rate medical proton synchrotron

Examples

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Embodiment Construction

[0022] Below in conjunction with the accompanying drawings, preferred embodiments of the present invention are given and described in detail.

[0023] like figure 1 As shown, the ultra-high dose rate medical proton synchrotron according to a preferred embodiment of the present invention includes a first deflection dipole magnet group A1, a second deflection dipole magnet group A2, and a third deflection dipole magnet group A3 connected in sequence and the fourth deflection dipole magnet group A4, and the fourth deflection dipole magnet group A4 is connected with the first deflection dipole magnet group A1 to form an annular structure. In this embodiment, the first deflection dipole magnet group A1 is composed of a first deflection diode magnet 11 and a second deflection diode magnet 12 with a deflection angle of 45 degrees, which are connected in series, and the second deflection diode magnet group A2 is composed of a deflection The third deflection dipole magnets 13 and the ...

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Abstract

The invention relates to an ultrahigh-dose-rate medical proton synchrotron which comprises four deflection dipolar magnet sets sequentially connected to form an annular structure. Each deflection dipolar magnet set is composed of at least two deflection dipolar magnets, the sum of deflection angles of the deflection dipolar magnets is 90 degrees, and four linear joints are connected between the adjacent deflection dipolar magnet sets. Each straight section comprises a horizontal focusing quadrupole magnet and a horizontal defocusing quadrupole magnet, protons are injected into the ultrahigh-dose-rate medical proton synchrotron through the injection cutting magnet and the injection impact magnet, and energy is increased under the action of the high-frequency acceleration device. Under the action of the leading-out impact magnet, the proton enters the leading-out cutting magnet and is led out from the ultrahigh-dose-rate medical proton synchrotron, and the cycle frequency is as high as 25Hz. According to the ultrahigh-dose-rate medical proton synchrotron, 25Hz fast circulation and fast leading-out are realized, and the requirements of small beam envelope function, low requirement on the inner diameter of a vacuum chamber and the like are met.

Description

technical field [0001] The present invention relates to tumor treatment, and more particularly, to an ultra-high dose rate medical proton synchrotron. Background technique [0002] The excellent Bragg peak characteristics of protons in the depth direction make them one of the most advanced means of tumor treatment. At present, more and more proton therapy devices and treatment centers are being built in the world, and proton therapy is also moving towards more precision and fewer side effects. development in a small direction. Flash therapy (FLASH) or ultra-high dose rate therapy is one of them. The non-patent document Sci Transl Med 2014;6:245ra93 shows that this treatment with an average dose rate greater than 60 Gy / s can kill tumor cells while reducing side effects in normal tissues. The non-patent document Appl.Phys.Lett.101, 243701 gives an instantaneous dose rate of 10 8 Gy / s, the average dose rate is not high but can also achieve good results. [0003] The high do...

Claims

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Application Information

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IPC IPC(8): H05H13/04H05H13/02A61N5/10
CPCH05H13/04H05H13/02A61N5/10A61N2005/1087
Inventor 张满洲欧阳联华陈志凌赵振堂李瑞史莹
Owner SHANGHAI ADVANCED RES INST CHINESE ACADEMY OF SCI
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