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Hormone double-item controlled-release regulating patch and preparation method thereof

A hormone and patch technology, applied in the field of hormone regulating drugs, can solve problems such as easy side effects, poor regulation effect, and failure to achieve the expected effect, and achieve the effect of being conducive to industrialization and simple operation

Pending Publication Date: 2021-08-13
广州德蔓生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the existing foods or medicines used for hormone regulation have relatively poor regulating effects, cannot achieve the expected effect, and are prone to side effects after use

Method used

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  • Hormone double-item controlled-release regulating patch and preparation method thereof
  • Hormone double-item controlled-release regulating patch and preparation method thereof

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preparation example Construction

[0029] The present invention also discloses a preparation method of the above-mentioned dual-term controlled-release hormone patch, comprising the following steps:

[0030] (1) Preparation of extract: according to the composition of the raw materials of the adjustment preparation layer, weigh out red peony root, triangularis, curcuma, frankincense, musk, northern Bupleurum, resurrection grass, chicory, avocado flower, red ginseng, rhodiola, epimedium, American soybean germ, Indian ginseng, Thai pueraria root and diosgenin were mixed and crushed to 10-25 μm and then added with 15-18 times the weight of ethanol aqueous solution, heated to 80-87°C for reflux extraction for 3-4 times, filtered and the filtrate was combined and concentrated to The solid content of 62-67% is the extract; wherein, the volume fraction of the ethanol aqueous solution is 75%;

[0031] (2) Preparation of gel: according to the gel raw material composition, take by weighing material xanthan gum, konjac pow...

Embodiment 1

[0035] Embodiment 1 of the present invention discloses a dual-phase controlled release regulating patch for hormones, which includes a PE film and a TPU film disposed on the PE film. The TPU film is pre-coated with a pressure-sensitive adhesive, and then a regulating preparation layer is applied to adjust the The preparation layer is covered with a release film, and the conditioning preparation layer includes the following components by weight: 35 parts of extract, 210 parts of gel, 0.5 part of emulsifier and 12 parts of glycerin;

[0036] Wherein, the extract is prepared from the following raw materials in parts by weight: 3 parts of Radix Paeoniae Alba, 5 parts of Sanleng, 6 parts of Curcuma, 2 parts of Frankincense, 7 parts of Musk, 3 parts of Bupleurum chinensis, 5 parts of Resurrection Grass, 8 parts of Chicory, 4 parts Avocado Blossom, 2 parts Red Ginseng, 3 parts Rhodiola, 6 parts Epimedium, 1 part American Soybean Germ, 1.5 parts Indian Ginseng, 1.5 parts Thai Pueraria,...

Embodiment 2

[0044] Embodiment 2 of the present invention discloses a dual-phase controlled-release hormone regulating patch, which includes a PE film and a TPU film disposed on the PE film. The TPU film is pre-coated with pressure-sensitive adhesive, and then a regulating agent layer is coated to adjust the The preparation layer is covered with a release film, and the conditioning preparation layer includes the following components by weight: 58 parts of extract, 230 parts of gel, 0.8 part of emulsifier and 15 parts of glycerin;

[0045] Wherein, the extract is prepared from the following raw materials in parts by weight: 8 parts of red peony root, 7 parts of triangularis, 10 parts of curcuma, 5 parts of frankincense, 10 parts of musk, 6 parts of Bupleurum chinensis, 11 parts of resurrection grass, 10 parts of chicory, 9 parts Avocado Blossom, 5 parts Red Ginseng, 5 parts Rhodiola, 9 parts Epimedium, 2 parts American Soybean Germ, 3 parts Indian Ginseng, 2 parts Thai Pueraria, and 0.8 part...

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Abstract

The invention discloses a hormone double-item controlled-release regulating patch and a preparation method thereof, and relates to the technical field of hormone regulating medicines. The hormone double-item controlled-release regulating patch comprisesa a PE film and a TPU film arranged on the PE film, wherein the TPU film is coated with a pressure-sensitive adhesive in advance and then coated with a regulating preparation layer, and the regulating preparation layer is covered with a release film, and comprises extract, gel, an emulsifier and glycerin. The extract is prepared from the following raw materials: radix paeoniae rubra, rhizoma sparganii, curcuma zedoary, frankincense, musk, bupleurum chinense, selaginella lepidophylla, endive, avocado flower, radix ginseng rubra, rhodiola rosea, herba epimedii, American soybean germ, Indian ginseng, Thailand pueraria mirifica and dioscin. The invention also discloses the preparation method of the hormone double-item controlled-release regulating patch, and the preparation method disclosed by the invention is easy to operate and beneficial to industrial popularization.

Description

technical field [0001] The invention relates to the technical field of hormone regulating medicines, in particular to a hormone dual-term controlled release regulating patch and a preparation method thereof. Background technique [0002] Female hormones are secreted by the ovaries and are the main components responsible for female development, maintenance of the female reproductive system and secondary characteristics of women. Removal of ovaries or imbalance of ovarian secretion of female hormones will result in insufficient hormones in some women, resulting in hot flashes, flushing, disturbed sleep, even insomnia, easy anger, sweating, genitourinary atrophy, dyspareunia, pain, urinary incontinence, etc. symptom. Therefore, it is necessary to adjust the hormones in women's body in time, otherwise it is easy to cause cardiovascular and cerebrovascular diseases, vaginal gland atrophy, osteoporosis caused by increased calcium ion flow and endometrial cancer after menstruation...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K47/36A61P5/24A61P15/08A61K9/70A61K31/7048A61K35/55
CPCA61K36/71A61K36/65A61K36/902A61K36/9066A61K36/324A61K35/55A61K36/233A61K36/11A61K36/28A61K36/54A61K36/258A61K36/41A61K36/296A61K36/48A61K36/488A61K31/7048A61K9/7023A61K47/36A61P15/08A61P5/24A61K2300/00
Inventor 郑玉娟
Owner 广州德蔓生物科技有限公司
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