Dose optimization method of radiotherapy interventional surgical robot in radioactive particles and medium

Abstract

The invention relates to a dose optimization method of a radiotherapy interventional surgical robot in radioactive particles and a medium. The dose optimization method comprises the steps of particle dose calculation and particle dose optimization. The particle dose calculation comprises the following steps: calculating radiation doses of various radioactive source particles with different types and different shapes through Monte Carlo simulation; wherein the particle dose optimization comprises the steps of constructing a three-dimensional topological structure of radioactive source particles, setting a superposition rule of a radioactive particle radiation field, setting a corresponding objective function according to a focus, and setting a boundary constraint condition; according to the three-dimensional topological structure, the superposition rule, the objective function and the boundary constraint condition, carrying out an annealing algorithm sequentially executing random particle source arrangement initialization, corresponding parameter setting of the simulated annealing process and iterative optimization processing of the simulated annealing algorithm, thus acquiring the optimal source arrangement plan and the optimal dosage of radioactive source particles. The method has the beneficial effects that the optimal particle source arrangement planning and dosage of the radiotherapy interventional surgical robot in the radioactive particles are realized.

Description

technical field [0001] The invention relates to the fields of medical treatment and computer, in particular to a dose optimization method and a medium of an interventional operation robot for radioactive particle internal radiotherapy. Background technique [0002] Malignant tumor has become a common multiple disease that seriously threatens human health, and its main treatment methods include surgery, chemotherapy and radiation therapy. Among them, radiotherapy uses high-energy rays emitted by radioactive sources to continuously destroy the nucleus of tumor cells and inhibit the mitosis of tumor cells, thereby achieving a therapeutic effect. Compared with ordinary external radiation therapy, radioactive seed implantation internal radiation therapy can greatly increase the radiation dose to tumor lesions, and at the same time reduce the radiation received by patients' normal organs and tissues, and has a high local control rate for malignant tumors, and post-treatment compli...

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Problems solved by technology

[0003] Although there are existing methods for optimizing particle radiation dose in internal radiotherapy, the existing methods do not consider the relevant limitations in clinical treatment, so there are still deficiencies in the practical application of assisting doctors or surgical robots in surgical operations

For example, in the actual particle implantation surgery, radioactive particles are injected into the lesion by a puncture needle. Most of the existing dose optimization methods are based on the coplanar needle optimization method, which cannot realize the distribution source optimization at any position in three dimensions. In the face of multiple lesions, large tumors, and occlusion of bones or important organs, it is difficult for the dose planning method to make the dose distribution meet the clinical requirements, and it is easy to appear cold areas of dose radiation

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