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Drug balloon catheter, drug balloon catheter system and control method of drug balloon catheter system

A balloon catheter and drug technology, applied in the direction of balloon catheters, catheters, etc., can solve the problems of low drug utilization rate, inconvenient clinical use, poor drug absorption effect, etc., to promote absorption, improve drug utilization rate, prevent Shedding effect

Active Publication Date: 2021-07-16
SONOSEMI MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the embodiment of this application is to provide a drug balloon catheter to solve the problems of low drug utilization, poor drug absorption effect and clinical problems existing in the prior art. Inconvenient technical issues

Method used

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  • Drug balloon catheter, drug balloon catheter system and control method of drug balloon catheter system
  • Drug balloon catheter, drug balloon catheter system and control method of drug balloon catheter system
  • Drug balloon catheter, drug balloon catheter system and control method of drug balloon catheter system

Examples

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Effect test

Embodiment 1

[0056] Please refer to figure 1 , the application provides a drug balloon catheter, including a balloon 20, a catheter 1 and a shock wave component 3, wherein the catheter 1 runs through the balloon 20, and the shock wave component 3 is located inside the balloon 20 and connected to the catheter 1, please also refer to figure 2 , the outer surface of the balloon 20 is coated with a drug coating 21, the drug coating 21 includes a protective layer 212 and a drug-loaded layer 211, and the drug-loaded layer 211 is located between the outer surface of the balloon 20 and the protective layer 212, that is, the balloon The outer surface of 20, the drug-loaded layer 211 and the protective layer 212 are adjacently arranged in sequence. In specific applications, the drug on the drug balloon catheter can be divided into three parts according to the flow direction of the drug: the first part is that during the delivery and withdrawal of the drug balloon catheter, due to the flushing effe...

Embodiment 2

[0080] This embodiment provides a drug balloon catheter. The difference between this embodiment and Embodiment 1 is that please refer to Image 6 , the drug coating 21 includes an active drug and a polymer carrier, the active drug can be uniformly mixed with the polymer carrier and then sprayed on the outer surface of the balloon 20, so that the outer surface of the balloon 20 forms a stable drug coating 21, The polymer carrier in the drug coating 21 can make the active drug adhere to the surface of the balloon 20 stably, effectively prevent the drug coating 21 from falling off due to blood flushing, and prevent the waste of the active drug. At the same time, the drug coating 21 of this embodiment can fall off from the outer surface of the balloon 20 under the action of the shock wave, so as to promote the absorption of the active drug by the blood vessel tissue, and the shock wave can also crush the excipient to a smaller size, avoiding its The downstream blood vessels gather...

Embodiment 3

[0085] This embodiment provides a drug balloon catheter. The difference between this embodiment and Embodiment 1 and Embodiment 2 is that please refer to Figure 7 , the drug coating 21 includes active drugs and liposomes 213 for encapsulating the active drugs, specifically, the liposomes 213 can be in the shape of hollow spheres, the active drugs can be located inside the liposomes 213, and the liposomes 213 have targeting Sex, sustained release and cell affinity, and liposome 213 has a certain sensitivity to shock waves. Under the action of shock waves, liposome 213 will disperse and transfer to the tissue, and then rupture, releasing its internal Active drugs, effective tissue absorption rate of active drugs, improve surgical effect.

[0086]Optionally, as one of the optional implementations of this embodiment, liposome 213 can use at least one of cholesterol, lecithin, soybean lecithin, cephalin, polyvinyl alcohol, polylactic acid-glycolic acid copolymer , the size of lip...

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Abstract

The invention provides a drug balloon catheter, a drug balloon catheter system and a control method of the drug balloon catheter system. The drug balloon catheter comprises a balloon with the outer surface coated with a drug coating, a catheter body penetrating through the balloon and a shock wave component connected to the catheter body, wherein the shock wave component is used for emitting shock waves to the drug coating after the catheter body is conveyed to a preset position, so that the drug coating falls off from the outer surface of the balloon; the drug coating comprises a protective layer and a drug carrying layer, and the drug carrying layer is located between the outer surface of the balloon and the protective layer; or the drug coating comprises an active drug and a polymer carrier; or the drug coating comprises an active drug and a liposome for wrapping the active drug; and the drug balloon catheter system comprises a control assembly and the drug balloon catheter, and the shock wave component is connected to the control assembly through a wire. The drug balloon catheter, the drug balloon catheter system and the control method of the drug balloon catheter system have the advantages of being high in medicine utilization rate, simple in structure and convenient to operate.

Description

technical field [0001] The present application belongs to the field of medical devices, and more specifically relates to a drug balloon catheter, a drug balloon catheter system and a control method thereof. Background technique [0002] Percutaneous Transluminal Angioplasty (PTA) has gone through the stages of bare balloon, bare metal stent, drug-eluting stent, and drug-coated balloon since the 1970s. Among them, Drug Coated Balloon (DCB), on the one hand, drugs can effectively inhibit the excessive proliferation of smooth muscle cells to reduce the incidence of restenosis; The risk of stent thrombosis is reduced, the time of dual antiplatelet is shortened, and the risk of bleeding is reduced. [0003] The existing drug balloons usually use the contrast agent iopromide as a carrier and paclitaxel as a drug coating to coat on the balloon catheter to treat coronary restenosis. The transfer rate of paclitaxel to vascular tissue ensures the effectiveness of the product in clin...

Claims

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Application Information

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IPC IPC(8): A61M25/10
CPCA61M25/1018A61M25/104A61M2025/105A61M2025/1079
Inventor 胡军刘斌
Owner SONOSEMI MEDICAL CO LTD
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