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A strain of streptococcus sp.64 and its application

A technology of streptococcus and fermentation broth, applied in the field of microorganisms

Active Publication Date: 2022-02-22
HAINAN MEDICAL UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, with people's long-term research and development, obtaining new antibacterial active substances has gradually become a major problem in microbial screening.

Method used

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  • A strain of streptococcus sp.64 and its application
  • A strain of streptococcus sp.64 and its application
  • A strain of streptococcus sp.64 and its application

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Embodiment Construction

[0027]The present invention will be further described below in conjunction with specific examples, so as to better understand the present invention.

[0028] The invention provides a streptococcus, which is a new species in the genus Streptococcus, named: Streptococcussp. -09-16. The Streptococcus sp.64 of the present invention is obtained by separating and screening the intestinal tract samples of Rattus norvegicus in the central mountainous area of ​​Hainan Island.

[0029] 1 Morphological Observation of New Species of Streptococcus

[0030] 1.1 Source of strain

[0031] Intestinal specimens of Rattus norvegicus from Hainan Island. Take the intestinal mucosal specimen of healthy adult Rattus norvegicus, cut the intestinal tissue of Rattus norvegicus by aseptic operation and put it into a grinder for grinding (about 20mg). Dilute, then transfer to a 2ml sterile centrifuge tube filled with 1.5ml PBS, vortex at high speed, then centrifuge at 1500rpm at low speed, carefully ...

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Abstract

The invention provides a streptococcus, which is a new species in the genus Streptococcus, named: Streptococcus sp.64, which is registered and preserved in the Guangdong Provincial Microorganism Culture Collection Center, and the preservation number is GDMCC No: 61194. The Streptococcus sp.64 of the present invention can produce strong antibacterial active substances after being fermented and cultured, and has obvious antibacterial effect on Pseudomonas aeruginosa and Burkholderia melioidosis, etc. The prevention and treatment of diseases caused by Pseudomonas and Burkholderia melioidosis has a broad development space, and has a good development and application prospect in the aspect of antibacterial drugs.

Description

technical field [0001] The invention belongs to the field of microorganisms, and in particular relates to a strain of Streptococcus sp.64 and its application. Background technique [0002] Streptococcus is the type genus of Firmicutes, Bacilli, Lactobacillales, and Streptococcusaceae. The genus Bacteria is a common type of pyogenic coccus, which widely exists in nature, human and animal feces and nasopharynx of healthy people, and most of them are not pathogenic. Medically important streptococci mainly include Streptococcus pyogenes, Streptococcus viridans, Streptococcus pneumoniae, and Streptococcus agalactiae. With the continuous progress and development of bacterial isolation and identification methods, especially the wide application of molecular classification and identification methods, more and more streptococci have been discovered. At the same time, as of 2020, the genus has included 160 species and 29 subspecies (http: / / www.bacterio.net / streptococcus.htmL). Rese...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/20A61K35/744A61P31/04C12R1/46
CPCA61K35/744A61P31/04
Inventor 牛莉娜轩断断张勇吕刚胡守奎尹飞飞杜江张云唐川宁崔秀吉黄艺彭箬岩
Owner HAINAN MEDICAL UNIV
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