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Soluble noninvasive acne-removing microneedle patch and preparation method thereof

A micro-needle patch and acne-removing technology, applied in the field of skin care products, can solve the problems of narrow application scenarios, labor-intensive, and insignificant improvement in efficiency, and achieve the effects of refreshing skin, reducing contact with pollution, and soothing skin discomfort.

Pending Publication Date: 2021-07-09
无锡元旭生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the deficiencies of the above-mentioned prior art, the present invention provides a dissolvable and non-invasive anti-acne microneedle patch and a preparation method thereof, the purpose of which is to solve the problems of existing acne-removing microneedle patches through iontophoresis, ultrasonic introduction, electroporation and micropowder supersonic velocity. In the process of injecting transdermal drug delivery to treat acne and acne skin problems, the application scenarios are narrow, the efficiency improvement is not obvious, sometimes large and expensive equipment is involved, and specially trained personnel are required to operate, which is a labor-intensive technical problem

Method used

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  • Soluble noninvasive acne-removing microneedle patch and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0022] The specific technical scheme of the soluble and non-invasive acne-removing microneedle patch provided in this embodiment is as follows:

[0023] The soluble and non-invasive acne microneedle patch includes the following ingredients by weight percentage: 60% sodium hyaluronate with large, medium and small molecular weight, 5% hydrolyzed collagen, 10% glycerin, and 24% functional ingredients. The functional ingredients include: Centella asiatica extract, aloe vera extract, encapsulated salicylic acid, quaternium-73 and azelaic acid in a ratio of 10:10:4:0.1:1.

[0024] The preparation method of the above-mentioned soluble non-invasive acne microneedle patch comprises the following steps:

[0025] S1, add hydrolyzed collagen and glycerin into water and heat up to 40°C, add large, medium and small molecular weight sodium hyaluronate, fully dissolve and stir evenly, cool down to room temperature, add functional ingredients, stir evenly, and sterilize fully with ozone to obt...

Embodiment 2

[0030] The specific technical scheme of the soluble and non-invasive acne-removing microneedle patch provided in this embodiment is as follows:

[0031] The soluble non-invasive acne microneedle patch includes the following ingredients by weight percentage: 66% sodium hyaluronate of large, medium and small molecular weight, 20% polyvinylpyrrolidone, 3% glycerin, 11% functional ingredients, functional ingredients Contains Centella Asiatica Extract, Aloe Vera Extract, Encapsulated Salicylic Acid, Quaternium-73 and Azelaic Acid in a 20:20:2:0.06:1 ratio.

[0032] The preparation method of the above-mentioned soluble non-invasive acne microneedle patch comprises the following steps:

[0033] S1, add polyvinylpyrrolidone and glycerin to water and heat up to 80°C, add large, medium and small molecular weight sodium hyaluronate, fully dissolve and stir evenly, cool down to room temperature, add functional ingredients, stir evenly, and sterilize fully with ozone to obtain soluble Non...

Embodiment 3

[0038] The specific technical scheme of the soluble and non-invasive acne-removing microneedle patch provided in this embodiment is as follows:

[0039] The soluble non-invasive acne microneedle patch includes the following ingredients by weight percentage: 80% sodium hyaluronate of large, medium and small molecular weight, 5% polyvinyl alcohol, 5% glycerin, 10% functional ingredients, functional ingredients Contains Centella Asiatica Extract, Aloe Vera Extract, Encapsulated Salicylic Acid, Quaternium-73 and Azelaic Acid in a ratio of 10:10:3:0.1:2.

[0040] The preparation method of the above-mentioned soluble non-invasive acne microneedle patch comprises the following steps:

[0041] S1, add polyvinyl alcohol and glycerin to water and heat up to 60°C, add large, medium and small molecular weight sodium hyaluronate, fully dissolve and stir evenly, cool down to room temperature, add functional ingredients, stir evenly, and sterilize fully with ozone to obtain soluble non-invas...

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Abstract

The invention belongs to the technical field of skin care products, and particularly relates to a soluble noninvasive acne-removing microneedle patch and a preparation method thereof. According to the soluble noninvasive acne-removing microneedle patch provided by the invention, tiny crystalline solids rich in acne-inhibiting components are distributed, and the wrapped active acne-removing components can penetrate through the cuticle of the skin, are dissolved in water, can be quickly and effectively absorbed by the skin, and inhibit acnes from the deep layer of the skin. When the microneedle patch is used in the initial period of acnes, the formation of acnes and acne marks can be reduced. The patch is tightly attached and invisible, the contact between acnes and external pollution can be reduced while acne secretions are absorbed, the skin discomfort is relieved, acne marks are faded, and the skin is refreshed to be in a fresh, cool and fine state. The microneedle patch not only has urgent research value, but also has good economic benefit and industrial application potential, which is the power and the basis for completing the method.

Description

technical field [0001] The invention belongs to the technical field of skin care products, and in particular relates to a soluble and non-invasive acne-removing microneedle patch and a preparation method thereof. Background technique [0002] The academic name of acne is Acne vulgaris (Acne Vuglaris), which is the most common chronic inflammatory disease of the pilosebaceous glands in dermatology. Acne, papules, pustules, nodules, cysts, and scars are the characteristics, often accompanied by seborrhea, and occur in puberty, also known as "acne". [0003] Acne occurs more frequently in adolescent males and females, with no gender difference, but females have an earlier age of onset than males. According to the national survey on the incidence of acne among college students, about 41% of college students will have acne, the incidence rate of boys is slightly higher at 42%, and the incidence rate of women is 40%. The incidence of acne among adolescents aged 10-18 is slightly...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/9789A61K8/9794A61K8/368A61K8/362A61K8/49A61K8/02A61Q19/00A61P17/10
CPCA61K8/735A61K8/9789A61K8/9794A61K8/368A61K8/362A61K8/49A61K8/0208A61Q19/00A61P17/10
Inventor 赵科研杨淑艳郭文平吴悦
Owner 无锡元旭生物技术有限公司
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