Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Experimental method for clinical application of mesenchymal stem cells to infantile autism

A kind of stem cell, clinical application technology, applied in the field of clinical application, can solve problems such as low immunogenicity

Pending Publication Date: 2021-07-02
吴志新 +1
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] As a kind of adult pluripotent stem cells, mesenchymal stem cells are capable of self-renewal and multi-directional differentiation. They come from a wide range of sources, are easy to isolate and culture in vitro, and have low immunogenicity. They have the functions of tissue damage repair and immune regulation. These characteristics make them It has potential application value in the treatment of children with autism. However, most of the research only involves basic research and animal experiments. So far, there are very few related studies on the clinical application of mesenchymal stem cells in the treatment of children with autism, and most of them are individual cases. to report

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: This example provides an experimental method for the clinical application of mesenchymal stem cells to children with autism. The experimental steps are:

[0029] S1: Select the experimental group and the comparison group. The subjects of the experimental group are children diagnosed with autism, and the subjects of the comparison group are children without autism. The experimental group is randomly divided into the control group, the drug group 1 and the drug group. 2 teams;

[0030] The selected objects are volunteer children recruited from the First Affiliated Hospital of Xi'an Medical College and Xi'an Center from 2019 to 2020. The recruited objects are male or female aged 3-12. The criteria for the recruitment of the experimental group are: diagnosed as autistic According to the diagnostic criteria for autism in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), the Childhood Autism Rating Scale (CARS) score is 30.

[...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an experimental method for clinical application of mesenchymal stem cells to infantile autism. According to the experimental method, by investigating the treatment condition of mesenchymal stem cells to infantile autism from multiple aspects of gene expression and serum indexes, the effect of the mesenchymal stem cells on improving and repairing serum series factor levels in the bodies of children with autism is investigated, so that practical basis is provided for treating autism by using the mesenchymal stem cells, the treatment theory is perfected, and basis is provided for clinical application of the stem cells.

Description

technical field [0001] The invention relates to the technical field of clinical application, in particular to an experimental method for the clinical application of mesenchymal stem cells to children with autism. Background technique [0002] Autism disorder (ASD) is defined as a complex behavioral disorder of repetitive behaviors characterized by severe and pervasive impairments in social communication. Autism is one of the most common mental illnesses. According to the latest statistics from the U.S. Centers for Disease Control, 1 in 59 8-year-olds has the disease. ASD is a complex and heterogeneous mental disorder, and early studies have shown that genetic and congenital factors are part of the etiology of autism. However, there is growing evidence that previous studies may have overestimated the genetic component of autism because autistic twins are genetically similar but also share an environment. At the same time, genome-wide studies have also uncovered a large num...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/28A61P25/00
CPCA61K35/28A61P25/00
Inventor 吴志新孙靖
Owner 吴志新
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com