Composite traditional Chinese medicine patch for treating epidermis thickening and pruritus dermatosis

Abstract

A composite traditional Chinese medicine patch for treating epidermis thickening and pruritus dermatosis belongs to an external Chinese patent medicine preparation, and is prepared by the following steps: crushing cortex dictamni, radix sophorae flavescentis, radix rehmanniae, angelica sinensis, salvia miltiorrhiza, raw liquorice, dark plum and the like, extracting, percolating, concentrating and the like to prepare thick paste, mixing the thick paste with borneol and matrix lanolin to obtain finished paste, and filling the finished paste with a traditional Chinese medicine preparation for treating epidermis thickening and pruritus dermatosis; mixing the finished paste with a pressure-sensitive acrylic polyurethane adhesive, coating a non-woven fabric backing with the mixture, carrying out hot drying, cutting the mixture into blocks, covering the blocks with protective paper, carrying out packaging, carrying out cobalt-60 disinfection and the like so as to prepare the composite traditional Chinese medicine patch. In order to solve the problems that the effect of externally applied liniments and patches for treating epidermis thickening and itching skin diseases (mainly including neurodermatitis (limitation), chronic eczema (moss-like change), psoriasis (common type) and the like) is limited or side effects are caused due to hormone contained, a pure traditional Chinese medicine formula is adopted in the development of the product, and the process is optimized; and a patch is prepared by matching with a safe pressure-sensitive adhesive with excellent performance, so as to provide an externally applied drug variety with a more accurate and safer effect for the treatment of the skin diseases.

Description

[0001] The invention relates to an improved compound traditional Chinese medicine patch for treating epidermis thickening and pruritus skin diseases, and belongs to the technical field of pharmaceutical preparations for external use. [0002] technical background [0003] Thickened epidermis pruritic dermatosis is a type of skin disease characterized by significant skin itching and thickened epidermis. Common neurodermatitis, chronic eczema, lichen planus, and pruritus are common. Some of these diseases are mainly characterized by pruritus without primary inflammatory pathological changes such as neurodermatitis (also known as lichen simplex chronica), but small inflammatory papules usually appear during the development of the disease; There may be a pathological basis of primary allergy such as chronic eczema, lichen planus and psoriasis; and simple pruritus. In the category of inflammatory epidermal thickening skin diseases, long-term chronic skin itching and thickening of th...

AI Technical Summary

Problems solved by technology

But the disadvantage is that these varieties, such as Piyanning tincture and these two patches, are prone to allergies and patients often have to discontinue use

Analyzing the reasons, first, these varieties contain salicylic acid ingredients, which are irritating to the skin and are also prone to skin allergies; second, the pressure-sensitive adhesive ingredients contained in the patch contain allergenic ingredients

In addition, because these varieties all contain glucocorticoids, long-term use is prone to local and systemic side effects such as skin thinning and atrophy, telangiectasia, etc. Patients are also afraid of using such hormone-containing external medicines.

Although the newer variety of camphor eucalyptus fluoride easy plaster uses several traditional Chinese medicine raw materials such as eucalyptus leaf oil, borneol, camphor, etc., the medicinal power of these raw materials is too weak, and the formula is too simple. and salicylic acid ingredients, making the defects more obvious

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