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Medical trauma hemostasis composite dressing

A trauma and composite polymer technology, applied in the field of medical supplies, can solve the problems of non-antibacterial wound healing, limiting the effective use of dressings, and adhesion between dressings and wounds, achieving hemostasis speed and promoting wound healing, high water absorption, The effect of fast hemostasis

Active Publication Date: 2021-05-04
HENAN YADU IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The skin provides protection for the human body. Once the skin is injured, it will have a great impact on body functions; therefore, after the skin is injured, it is necessary to protect the wound in time to avoid infection of the wound; medical dressings are used as a temporary treatment for wounds. Medical materials, its main function is to control wound exudate, accelerate wound hemostasis, protect the wound surface from bacterial and dust contamination of the wound, and promote wound healing; currently commonly used wound repair supplies include natural fiber dressings (gauze), synthetic fiber dressings , gel dressing and sponge dressing; natural cellulose such as gauze mainly acts as a physical barrier to the wound, does not have antibacterial and wound healing effects, and has poor affinity with the wound; synthetic fiber dressing Usually prepared from biopolymer materials, it has good affinity with the wound, but its permeability is high, and it is easy to cause the dressing to adhere to the wound when it is peeled off from the wound, and it is not easy to remove from the wound surface; gel dressing , is to form a gel through the dressing to absorb the wound exudate; this kind of dressing will have a colloid layer with a network structure formed after the surface dressing first contacts the wound to absorb liquid, which hinders the inner dressing from further absorbing liquid. This prevents the "fish-eye" phenomenon of the gel dressing; limits the effective utilization of the dressing;

Method used

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  • Medical trauma hemostasis composite dressing
  • Medical trauma hemostasis composite dressing
  • Medical trauma hemostasis composite dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Preparation of dandelion fluff / viscose fiber nonwoven fabric:

[0032] (1) After collecting 500 g of dandelion fluff and ultrasonically activating it in 0.5 mol / L sodium bicarbonate solution, wash until the washing solution is neutral, and obtain activated dandelion fluff after drying;

[0033] (2) opening treatment of activated dandelion fluff fiber (PR) and viscose fiber (VF);

[0034] (3) form short fibers evenly distributed in warp and weft after the fiber carding machine after opening is carded;

[0035] (4) the short fiber is laid into a fiber net through a web-laying machine;

[0036] (5) Put the fiber web into the spunlace machine and composite 2-4 times with spunlace on both sides; entangle dandelion fibers and viscose fibers together to obtain dandelion fluff / viscose fiber non-woven fabric base material; wherein, The pressure of spunlace is 2-3MPa, and the feeding and discharging speed is 14-16m / min;

[0037] The viscose fiber is prepared from crop stalks b...

Embodiment 2

[0044] Investigation of the amount of gluten added:

[0045] In 1000g 1wt% oxidized sodium alginate aqueous solution, add gluten protein part by part (0.1g / part) under stirring condition, along with the increase of gluten protein adding part, sol liquid viscosity increases gradually, when adding gluten protein amount is greater than 10 During the time, the gluten protein cannot completely dissolve and react, and the sol formed is uneven, and there is unreacted gluten protein powder in the sol; the present invention selects the addition ratio of gluten protein and oxidized sodium alginate to be less than 1: 10, preferably 0.5-1 : 10.

[0046] Preparation of composite biopolymer sol:

[0047] Get 0.5g gluten protein and add in 1000g 1wt% oxidized sodium alginate aqueous solution at 30-40 ℃ in 250r / min stirring reaction is complete and then add 125mL4wt% chitosan acetic acid solution (1wt% degree of deacetylation 85% chitosan and 3wt% % carboxymethyl chitosan) to obtain composi...

Embodiment 3

[0061] Preparation of medical trauma hemostatic composite dressing:

[0062] The non-woven fabrics J-1 to J-12 prepared in Example 1 were used as substrates, and the composite biopolymer sol R-2 prepared in Example 2 was coated on the surface, and the composite biopolymer sol R-2 was vacuumized in a vacuum device and then taken out. , hot rolled at 50-60°C under a three-stage roller press, dried and sterilized to obtain a medical hemostatic composite dressing; sequentially recorded as RJ-12, RJ-22, RJ-32, RJ-42, RJ-52, RJ-62, RJ-72, RJ-82, RJ-92, RJ-102, RJ-112, RJ-122;

[0063] The performance of the above-mentioned medical hemostatic composite dressing was tested, and the results are shown in Table 3.

[0064] table 3.

[0065]

[0066] It can be seen from the data in Table 3 that with the increase of the dandelion fluff content in the non-woven fabric substrate, the breaking strength of the dressing showed a decreasing trend, the air permeability first increased and th...

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Abstract

The invention discloses a medical trauma hemostasis composite dressing. The medical trauma hemostasis composite dressing is characterized in that dandelion fluff / viscose fiber non-woven fabric is used as a base material, non-woven fabric fibers and a surface layer are stuffed with a mucedin, oxidized sodium alginate and chitosan composite high polymer material in a vacuumizing mode, and the medical wound hemostasis composite dressing with high water absorption, good air permeability and antibacterial property is obtained. In addition, the medical trauma hemostasis composite dressing also has the effects of resisting adhesion, being high in hemostatic speed and promoting wound healing, and the wound healing time is shortened.

Description

technical field [0001] The invention belongs to the field of medical supplies, and in particular relates to a composite dressing for hemostasis of medical wounds. Background technique [0002] The skin provides protection for the human body. Once the skin is injured, it will have a great impact on body functions; therefore, after the skin is injured, it is necessary to protect the wound in time to avoid infection of the wound; medical dressings are used as a temporary treatment for wounds. Medical materials, its main function is to control wound exudate, accelerate wound hemostasis, protect the wound surface from bacterial and dust contamination of the wound, and promote wound healing; currently commonly used wound repair supplies include natural fiber dressings (gauze), synthetic fiber dressings , gel dressing and sponge dressing; natural cellulose such as gauze mainly acts as a physical barrier to the wound, does not have antibacterial and wound healing effects, and has po...

Claims

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Application Information

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IPC IPC(8): A61L15/40A61L15/28A61L15/32A61L15/44A61L24/00A61L24/08A61L24/10D04H1/4382D04H1/492
CPCA61L15/40A61L15/32A61L15/28A61L15/44A61L24/0015A61L24/0005A61L24/08A61L24/108D04H1/4382D04H1/492A61L2300/252A61L2300/232A61L2300/418A61L2300/412C08L89/00C08L5/04C08L5/08
Inventor 张正男段书霞潘红福闫钧付迎坤常聪周静储旭何孜翰周小婷刘康博林建香
Owner HENAN YADU IND
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