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A kind of veterinary povidone-iodine solution and preparation method thereof

A technology of povidone iodine and povidone, which is applied in the field of veterinary povidone iodine solution and its preparation, to achieve the effects of easy operation, increased effective iodine content, and good bactericidal effect

Active Publication Date: 2021-07-13
GUANGZHOU HESHENGTANG ANIMAL PHARMA
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, the povidone iodine solution still has the problem of rapid decomposition under low concentration and the stability needs to be improved. At the same time, it is easy to make the bacterial flora develop drug resistance when used in the breeding field. Therefore, it is necessary to further improve the safety and reduce the bacterial flora. Antimicrobial resistance, further improving the disinfection and sterilization effect

Method used

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  • A kind of veterinary povidone-iodine solution and preparation method thereof
  • A kind of veterinary povidone-iodine solution and preparation method thereof
  • A kind of veterinary povidone-iodine solution and preparation method thereof

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Embodiment 1-5

[0033] Follow the steps below to prepare povidone-iodine solution for veterinary use:

[0034] (1) Add povidone-iodine, povidone, polyglutamic acid, and malic acid in 60 g of sterilized water, and stir at 18°C ​​until completely dissolved to obtain mixture 1;

[0035] (2) Add disodium hydrogen phosphate, sodium dihydrogen phosphate, potassium iodate, and potassium iodide in 10 g of sterilized water, and stir at 32°C until completely dissolved to obtain mixture 2;

[0036] (3) Mix mixture 1 and mixture 2 to obtain mixture 3, add water to 100 g, and stir evenly to obtain the veterinary povidone-iodine solution.

[0037] Wherein, the formula of embodiment 1-5 is as shown in table 1:

[0038] Table 1.

[0039]

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Abstract

The invention discloses a veterinary povidone-iodine solution and a preparation method thereof, and belongs to the technical field of disinfectants. This veterinary povidone-iodine solution is composed of the following ingredients in mass percentage: povidone-iodine 8-12%, povidone 0.8-1.2%, cationic polymeric polypeptide 1.5-4%, malic acid 0.1-0.15%, Disodium hydrogen phosphate 0.03-0.08%, sodium dihydrogen phosphate 0.16-0.22%, potassium iodate 0.2-0.3%, potassium iodide 0.3-0.5% and the balance water. The preparation method includes: adding povidone-iodine, povidone, cationic polymeric polypeptide, and malic acid into water and dissolving it to obtain mixture 1; adding disodium hydrogen phosphate, sodium dihydrogen phosphate, potassium iodate, and potassium iodide into water and dissolving it to obtain mixture 2; Mix mixture 1 and mixture 2, add water until quantitative. This product has good bactericidal effect, significantly improved stability, increased effective iodine content, less resistance to drug resistance, and high safety.

Description

technical field [0001] The invention belongs to the technical field of disinfectants, and in particular relates to a veterinary povidone-iodine solution and a preparation method thereof. Background technique [0002] Povidone iodine (PVP-I), also known as polyvinylpyrrolidone iodine, is a complex of iodine element and 1-vinyl-2-pyrrolidone (PVP) homopolymer. The molecular structure of povidone-iodine is a relatively unique and stable structure, which is mainly a stable complex formed by polyvinylpyrrolidone and iodine with the help of hydrogen bonds and other attractive forces. Polyvinylpyrrolidone (PV P) is a nonionic surfactant, easily soluble in water, and iodine element is complexed with it, which improves the solubility of iodine element. In addition, the iodine element is combined on the inner side of the polyvinylpyrrolidone helical structure, which greatly enhances the stability of the iodine element. At the same time, this coating structure enables povidone-iodine...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/79A61K33/18A61K9/08A61K47/02A61P31/04C02F1/50A61K31/194A61K31/75A61K31/785
Inventor 高平陈振威李云梁金兰刘为和
Owner GUANGZHOU HESHENGTANG ANIMAL PHARMA
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