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A traditional Chinese medicinal ointment for treating chloasma and its preparation method and application

A technology of traditional Chinese medicine and astragalus, applied in the field of traditional Chinese medicine ointment for the treatment of chloasma and its preparation, can solve problems such as the inability to form a unified syndrome differentiation and treatment system, extremely high requirements for personal experience in acupuncture, and a large number of folk prescriptions, so as to facilitate adherence Taking, improving the chronic disease of chloasma, the effect of high drug concentration

Active Publication Date: 2022-04-15
LIAONING HUANREN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

External treatment methods are difficult to cure the root cause, and are often prone to relapse; acupuncture requires extremely high personal experience and is difficult to promote; in terms of internal treatment, most doctors only rely on personal experience for syndrome differentiation and treatment, and there are a large number of folk prescriptions, so it is impossible to form a unified Syndrome differentiation and treatment system, and the standard is difficult to grasp, and it is difficult to improve the cure rate

Method used

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  • A traditional Chinese medicinal ointment for treating chloasma and its preparation method and application
  • A traditional Chinese medicinal ointment for treating chloasma and its preparation method and application
  • A traditional Chinese medicinal ointment for treating chloasma and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0101] Example 1 Preparation method of traditional Chinese medicine formula granule ointment

[0102] Prescription dispensing: use traditional Chinese medicine formula granule dispensing equipment to carry out prescription dispensing and preparation according to the prescription quantity.

[0103] Redissolving: Add water 1.3 times the total weight of the granules into the pot of the cream square machine, set the temperature of the heat preservation and paste boiling to 55°C, set the time to 10 minutes, start heating and stirring, when the temperature reaches above 50°C, slowly Slowly add the adjusted Chinese medicine formula granules.

[0104] Boil ointment: After the granules are completely dissolved, set the heat preservation temperature and ointment boiling temperature to 80°C, and set the time (34 minutes / 500g granules), so that the medicinal solution will gradually become a thick clear ointment. (At this time, the refractive index should be measured by Abbe refractomete...

experiment example 1

[0138] Take the traditional Chinese medicine formula granule ointment prepared in Example 1 to carry out pharmacodynamic experiment research.

[0139] 1. Materials and reagents

[0140] 1.1 Materials and Instruments

[0141] Experimental animals: 50 Kunming female mice, SPF grade, weighing 30±2g, placed in the observation room for observation (room temperature 25±1°C, relative temperature 50-60%), natural light, day and night light and dark alternation time 12h, Free to eat and drink, well ventilated and clean. After 7 days, they were randomly divided into normal control group, model control group, low-dose group, middle-dose group and high-dose group, with 10 rats in each group.

[0142] Main instruments: electronic analytical balance (USA DENVER company), optical microscope digital camera system (Japan OLYMPUS), ACS-3H-B electronic scale (Zhongshan Jinli Electronic Scale Co., Ltd.), LG10-2.4 centrifuge (Beijing Medical Instrument Repair factory), three-purpose electric he...

Embodiment 2

[0176] The difference with Example 1 is that, compared with the prescription of Example 1, the prescription of Example 2 does not contain the six traditional Chinese medicines of Angelica sinensis, Chuanxiong, Peach kernel, safflower, motherwort, and turmeric.

[0177] 1. Prescription

[0178]

[0179]

[0180] 2. Preparation method

[0181] Take a total of 525.5g of formula granules according to the prescription, add 683.15g of warm water at 55°C, stir well to completely redissolve the granules, heat and boil the paste at 80°C for 36 minutes, add 78.8g of honey, 5.25g of citric acid, and continue for 80 Heat and cook at ℃ for 5.3 minutes to complete the collection of paste, and then pour it into a clean container while it is hot, and keep it sealed.

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Abstract

The present invention provides a traditional Chinese medicine ointment for treating chloasma and its preparation method and application. The ointment of the present invention is composed of thirty-five medicinal materials, and is used for stagnation of liver qi, deficiency of liver and kidney yin, and weak spleen and stomach, so that stasis and turbidity are internally stopped. Accumulation of the skin or emptiness of veins, failure to grow is the basic pathogenesis. According to traditional Chinese medicine, chloasma is between deficiency (qi deficiency, blood deficiency, spleen deficiency, liver and kidney deficiency) and excess (qi stagnation, damp accumulation, liver depression, blood stasis). The folder is the cause of the disease, and it is used to invigorate deficiency and relieve excess, nourish qi and blood, beautify and nourish the skin, and remove spots and blemishes. The compatibility of the whole formula soothes the liver and invigorates the spleen, promotes blood circulation and removes blood stasis, regulates qi and blood, promotes dampness and promotes regeneration, and warms the kidney yang, thus helping to eliminate plaque. There are no problems such as dryness, heat and greasy stagnation.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicinal ointment for treating chloasma and its preparation method and application. Background technique [0002] The information disclosed in this background section is only intended to increase the understanding of the general background of the present invention, and is not necessarily taken as an acknowledgment or any form of suggestion that the information constitutes the prior art already known to those skilled in the art. [0003] Melasma, also known as liver spots, is a yellow-brown pigmentation on the face. Multiple symmetrical butterflies are distributed on the cheeks. It is more common in women, and the main reason is high estrogen level in the blood. Its onset is related to pregnancy, long-term oral contraceptives, and menstrual disorders. Traditional Chinese medicine believes that the occurrence of chloasma is related to stagnation of liver qi, deficie...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/06A61K47/46A61K47/12A61P17/00A61K35/32A61K35/36
CPCA61K36/232A61K36/236A61K36/71A61K36/65A61K36/284A61K36/076A61K36/487A61K36/8969A61K36/64A61K36/54A61K36/533A61K36/39A61K36/43A61K36/481A61K36/752A61K36/9066A61K36/238A61K36/233A61K36/638A61K36/815A61K36/736A61K36/286A61K36/31A61K36/8984A61K36/575A61K36/804A61K36/9064A61K36/484A61K36/69A61K35/32A61K35/36A61K9/06A61K9/0053A61K47/46A61K47/12A61P17/00A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 赫爱平汪巍周书繁王辉杨玉
Owner LIAONING HUANREN PHARMA
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