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Externally applied traditional Chinese medicine composition for treating gynecological diseases, transdermal medicine delivery patch and application

A technology for gynecological diseases and compositions, which is applied in the direction of drug combinations, diseases, and medical preparations with non-active ingredients, etc., which can solve problems such as easy injury and stomach gas, difficulty in reaching hospitals, and long time of taking medicines, and achieve clinical compliance Good sex, high treatment efficiency, accurate and controllable effect

Pending Publication Date: 2021-02-05
FIRST PEOPLES HOSPITAL OF YUNNAN PROVINCE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The onset characteristics of gynecological diseases are mostly local lesions with fixed parts, such as: pelvic inflammatory disease, cervicitis, infertility, dysmenorrhea, etc. The lesions are close to the body surface, and traditional Chinese medicine is administered systemically, which is generally difficult to reach. And the time of taking the medicine is longer, it is easy to hurt the stomach qi, and it is difficult to persist at the same time. Therefore, external application of traditional Chinese medicine has increasingly attracted people's attention.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Corresponding to the above-mentioned principle of compatibility of traditional Chinese medicines, the externally applied Chinese medicine composition for treating gynecological diseases in this embodiment, by weight, includes 10 g of Radix Acanthopanax, 10 g of Qiannianjian, 30 g of Speranthema, 10 g of Notopterygium, 10 g of Duhuo, Cangxue 10g, frankincense 10g, myrrh 10g, safflower 30g, mugwort 30g, mulberry 10g, diapsacus 10g, trigonum 10g, curcuma 10g, red peony 10g, Sichuan pepper 6g, dandelion 10g, angelica dahurica 10g, windproof 10g .

[0048] The transdermal drug delivery patch made of the above-mentioned Chinese medicinal ingredients has the following steps in its preparation method:

[0049] Step1. Preparation of drug ultrafine powder: wash the above-mentioned Chinese medicine ingredients respectively, and dry them under normal pressure to make the water content less than 5%, and then crush the above-mentioned Chinese medicine ingredients in stages and gradie...

Embodiment 2

[0059] Corresponding to the above-mentioned principle of compatibility of traditional Chinese medicines, the externally applied Chinese medicine composition for treating gynecological diseases in this embodiment, by weight, includes 6.67g of Radix Acanthopanax, 6.67g of Qiannianjian, 20g of Speranthema, 6.67g of Notopterygium, Duhuo 6.67g, Guangxuejie 6.67g, Frankincense 6.67g, Myrrh 6.67g, Safflower 20g, Artemisia argyi 20g, Sangjisheng 6.67g, Dipsacus 6.67g, Sanleng 6.67g, Curcuma 6.67g, Radix Paeoniae Rubra 6.67g, Sichuan Pepper 4g, Dandelion 6.67g, Angelica dahurica 6.67g, Fangfeng 6.67g.

[0060] The preparation method and application steps of the transdermal patch are the same as in Example 1.

Embodiment 3

[0062] Corresponding to the above-mentioned principle of compatibility of traditional Chinese medicines, the external application of traditional Chinese medicine composition for the treatment of gynecological diseases in this embodiment, by weight, the above-mentioned 20g of Radix Acanthopanax, 20g of Qiannianjian, 60g of Speranthema, 20g of Notopterygium, 20g of Duhuo, 20g of dried blood, 20g of frankincense, 20g of myrrh, 60g of safflower, 60g of mugwort leaf, 20g of mulberry, 20g of Dipsacus, 20g of Sanleng, 20g of curcuma, 20g of red peony, 12g of Sichuan pepper, 20g of dandelion, 20g of angelica, and 20g of wind.

[0063] The preparation method and application steps of the transdermal patch are the same as in Example 1.

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PUM

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Abstract

The invention discloses an externally applied traditional Chinese medicine composition for treating gynecological diseases. The composition comprises the following traditional Chinese medicine components: cortex acanthopanacis, obscured homalomena rhizome, garden balsam stem, notopterygium root, radix angelicae pubescentis, daemonorops draco, frankincense, myrrh, safflower, folium artemisiae argyi, parasitic loranthus, teasel root, rhizoma sparganii, curcuma zedoary, radix paeoniae rubra, pericarpium zanthoxyli, dandelions, radix angelicae dahuricae and radix saposhnikoviae. A preparation method of a transdermal medicine delivery patch prepared from the traditional Chinese medicine components comprises the steps of preparing superfine medicine powder and preparing the patch. Besides, the invention further discloses application steps of the transdermal medicine delivery patch to treatment of gynecological diseases. The traditional Chinese medicine composition provided by the invention has a good curative effect and few side effects; According to the transdermal medicine delivery patch prepared from the traditional Chinese medicine composition, by means of an ultrasonic introductiontechnology, effective components in medicines permeate into deep tissues through local skin, so that relatively high medicine concentration is rapidly achieved, and the purpose of treatment is furtherachieved. A transdermal medicine delivery technology is good in directionality, accurate and controllable in action range, high in treatment efficiency, small in local irritation and good in clinicalcompliance.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to an externally applied traditional Chinese medicine composition for treating gynecological diseases, a transdermal drug delivery patch and its application. Background technique [0002] Smart transdermal drug delivery system (Smart transdermal drug delivery system TDDS) refers to drug delivery on the skin surface. Ultrasound generates ultrasonic transmission with variable intensity and frequency within a specified time to expand the surface skin pores, which is beneficial or convenient for drug delivery. Delivered to subcutaneous tissues and blood. Control can be achieved by adjusting the timing of the alternating waveforms to vary the intensity of the infiltration. Among them, the U-Strip ultrasonic belt developed abroad for diabetes uses special ultrasonic transmission through the insulin patch to expand the pores of the skin so that macromolecular drugs can penetrat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K47/38A61K36/9066A61P15/00
CPCA61K9/7046A61K47/38A61K36/254A61K36/888A61K36/47A61K36/185A61K36/237A61K36/232A61K36/889A61K36/896A61K36/324A61K36/328A61K36/286A61K36/282A61K36/902A61K36/9066A61K36/71A61K36/65A61K36/758A61K36/288A61K36/238A61P15/00A61K2300/00
Inventor 刘宇张俊王劲王真李娜熊学敏杨景然胡冬雄张加稳刘涛郭巍怡
Owner FIRST PEOPLES HOSPITAL OF YUNNAN PROVINCE
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