Reinforced micro-interface preparation system and method of polyglycolic acid

Abstract

The invention provides a reinforced micro-interface preparation system and method of polyglycolic acid. The reinforced micro-interface preparation system comprises a hydrogenation reactor, a hydrogenfeeding pipeline, a hydrolysis reactor and a water vapor feeding pipeline, an oxalate feeding pipeline is arranged on the side wall of the hydrogenation reactor, a micro-interface unit is arranged inthe hydrogenation reactor, and the micro-interface unit is formed by sequentially arranging a plurality of micro-interface generators from top to bottom; the hydrogen feeding pipeline penetrates through the side wall of the hydrogenation reactor and enters the micro-interface unit, so that hydrogen is crushed into micron-sized micro-bubbles in the micro-interface unit in advance before hydrogenation reaction. According to the enhanced micro-interface preparation system, the micro-interface unit is arranged in the hydrogenation reactor, and the micro-interface generator is arranged on the sidesurface of the hydrolysis reactor, so that hydrogen is crushed into micro-bubbles before hydrogenation reaction of hydrogen and dimethyl oxalate, and the phase boundary mass transfer area between hydrogen and dimethyl oxalate is increased.

Description

technical field [0001] The invention relates to the field of polyglycolic acid preparation, in particular to a polyglycolic acid enhanced micro-interface preparation system and method. Background technique [0002] Polyglycolic acid is a common biodegradable polyester widely used in high value-added fields such as surgical sutures, drug carriers and bone materials. Polyglycolic acid has a simple and regular linear molecular structure and is a simple linear aliphatic polyester. Polyglycolic acid with a molecular weight over 10,000 has strong mechanical strength and can be used in medical sutures. The industrial preparation of high molecular weight polyglycolic acid usually adopts the method of ring-opening polymerization of glycolide. [0003] China is a country with less oil and more coal. With the development of my country's coal-to-ethylene glycol industry, the use of intermediate product dimethyl oxalate to produce polyglycolic acid on a large scale can further promote ...

AI Technical Summary

Problems solved by technology

[0007] The first object of the present invention is to provide an enhanced micro-interface preparation system for polyglycolic acid. The enhanced micro-interface preparation system is equipped with a micro-interface unit inside the hydrogenation reactor, so that the hydrogenation reaction between hydrogen and dimethyl oxalate is carried out. Previously, hydrogen was broken into microbubbles to increase the mass transfer area of ​​the phase boundary between hydrogen and dimethyl oxalate, thus solving the problem of reaction pressure caused by hydrogen and dimethyl oxalate not being fully mixed inside the reactor in the prior art. High, high hydrogen-ester ratio, low liquid hourly space velocity

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