DNA storage method and system and storage medium

Abstract

The invention discloses a DNA storage method and system and a storage medium, and the method comprises the steps of carrying out the sequencing of synthetic DNA, and obtaining a plurality of sequencing sequences; determining that no corresponding sequencing base sequence exists in the coding table, and obtaining the base sequence with the smallest Hamming distance from the sequencing base sequencein the coding table to replace the sequencing base sequence; decoding the replaced sequencing sequence according to the coding table to obtain a decoded text, wherein the Hamming distance between anytwo base sequences in the character coding table is greater than a first threshold value. According to the embodiment of the invention, error correction is carried out on the sequencing base sequenceobtained by sequencing by utilizing the Hamming distance with the base sequence, and the sequencing base sequence after error correction is decoded to obtain a decoded text. Due to the fact that theHamming distance between any two base sequences in the coding table is larger than the first threshold value, the coding table has certain error correction capacity, and compared with existing redundant code error correction, the DNA storage efficiency is greatly improved. The invention can be widely applied to the field of molecular biology.

Description

technical field [0001] The invention relates to the technical field of molecular biology, in particular to a DNA storage method, system and storage medium. Background technique [0002] With the development of technologies such as cloud computing, big data, artificial intelligence and high-throughput sequencing, human beings have entered the era of big data. The demand for massive data storage poses a huge challenge to data storage technology. Although today's storage technology has a fast reading speed, the data storage device has a limited time to save data, occupies a large space, and is relatively expensive. Compared with it, DNA storage has the following significant advantages: saving space, 1 gram of DNA is less than the size of a dewdrop on a fingertip, but can store 700TB of data, which is equivalent to 14,000 50GB Blu-ray discs or 233 3TB hard drives; Cost saving, no power consumption, no manual maintenance; long storage time; high storage data density. [0003] ...

AI Technical Summary

Problems solved by technology

However, due to the problem that DNA strands are prone to base deletion, insertion and substitution errors during synthesis, storage and sequencing, most of the current research has added many redundant codes to the original input information, such as internal codes to solve sequence base errors within, external codes resolve sequence-level deletions

A large number of redundant codes lead to low storage efficiency of existing DNA storage

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