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A kind of nicotinamide composite fungicide, its preparation method and application

A compound fungicide and nicotinamide technology, which is applied in the field of personal care products, can solve the problems of poor water solubility of phenolic fungicides, unsatisfactory consumer acceptance, and high irritation of fungicides, achieving synergistic bactericidal effect and easy to use. Operation, unpleasant odor light effect

Active Publication Date: 2021-05-07
南京泛成生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Traditional phenolic fungicides are highly irritating and have an unpleasant smell. Long-term use on the skin can make the skin dry and sensitive, and the consumer acceptance is not ideal
On the other hand, due to the poor solubility of phenolic fungicides in water, their application is limited.

Method used

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  • A kind of nicotinamide composite fungicide, its preparation method and application
  • A kind of nicotinamide composite fungicide, its preparation method and application
  • A kind of nicotinamide composite fungicide, its preparation method and application

Examples

Experimental program
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Effect test

Embodiment 1

[0024] Example 1: 20 g of phenol, 36 g of glycerin, 12 g of alkyl glycosides, and the rest are deionized water.

Embodiment 2

[0025] Example 2: 20 g of chloroxylenol, 36 g of glycerin, 12 g of alkyl glucoside, and the rest are deionized water.

Embodiment 3

[0026] Example 3: 20 g of triclosan, 36 g of glycerin, 12 g of alkyl glucoside, and the rest are deionized water.

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PUM

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Abstract

The invention discloses a nicotinamide compound fungicide, its preparation method and application. The nicotinamide compound fungicide comprises, by mass fraction, 2-10% of nicotinamide, 5-25% of phenolic fungicide, 5-40% of polyol, and 2-20% of emulsifier. The preparation method comprises: heating, dissolving and mixing the phenolic fungicide and the polyhydric alcohol; adding an emulsifier and mixing evenly after cooling down; adding nicotinamide and mixing evenly. The nicotinamide composite bactericide prepared by the invention can obviously synergize the bactericidal effect of phenolic bactericides, has low irritation and lighter unpleasant smell, and is very suitable for application in wash-off products.

Description

technical field [0001] The invention belongs to the field of personal care products, and relates to a nicotinamide composite fungicide, a preparation method and application thereof. Background technique [0002] Niacinamide, also known as nicotinamide, is an amide compound of niacin. Clinically, it is mainly used to prevent and treat pellagra, stomatitis, glossitis, sick sinus syndrome, atrioventricular block and other problems. In the field of personal care, it is mainly used for whitening, moisturizing and enhancing skin resistance. [0003] Disinfection and sterilization products have always been popular products in the market. Traditional fungicides are mainly phenols, aldehydes and cationics. Phenolic active substances are the most widely used, mainly including phenol, chloroxylenol, triclosan and o-phenylphenol. [0004] Traditional phenolic fungicides are highly irritating and have an unpleasant smell. Long-term use on the skin can make the skin dry and sensitive,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N43/40A01N31/08A01N31/16A01P1/00C11D1/66C11D3/20C11D3/24C11D3/28C11D3/48C11D3/60
CPCA01N31/08A01N31/16A01N43/40C11D1/662C11D3/2034C11D3/2065C11D3/24C11D3/28C11D3/48
Inventor 樊媛媛
Owner 南京泛成生物科技有限公司
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