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Composite traditional Chinese medicine preparation as well as preparation method and application thereof

A technology of traditional Chinese medicine preparations and extracts, applied in the field of preparation and compounding traditional Chinese medicine preparations, can solve the problems of inability to improve other functions of the body, single treatment effect, side effects and the like

Inactive Publication Date: 2020-12-04
DALIAN NATIONALITIES UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine mostly uses astragalus, yam, kudzu root, atractylodes atractylodes, Atractylodes macrocephala, trichosanthum pollen, Scrophulariaceae, Poria cocos, etc. to lower blood sugar, and the therapeutic effect is too single
Moreover, most traditional Chinese medicines have great limitations in the control of diabetes because their main components are not enough to lower blood sugar, while western medicines based on insulin, sulfonylureas, and biguanides are single hypoglycemic drugs that cannot improve other functions of the body. , especially for diabetic complications, there is basically no therapeutic effect, and there are different degrees of side effects
Therefore, finding a drug ingredient with natural hypoglycemic properties and no side effects combined with traditional Chinese medicine to prepare a compound Chinese medicine preparation to solve the shortcomings of simple Chinese medicine treatment and Western medicine treatment has become the focus of current research.

Method used

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  • Composite traditional Chinese medicine preparation as well as preparation method and application thereof
  • Composite traditional Chinese medicine preparation as well as preparation method and application thereof
  • Composite traditional Chinese medicine preparation as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Weigh each raw material according to the following grams: Cornus officinalis 50g, Bitter gourd 50g, Rehmannia glutinosa 20g, Sanqi 25g, Lycium barbarum 20g, Salvia miltiorrhiza 25g, Angelica 25g, Polygonatum 25g, Ophiopogon japonicus 15g, Asparagus 15g, Huanglian 25g, Zhigancao 20g, lotus leaf 25g, Digupi 10g, hawthorn 20g, mulberry 20g, Eucommia 20g, burdock seed 15g, yam 25 parts. After removing impurities, add 3000ml of water, decoct with slow fire until the liquid medicine is 100ml, the temperature of the medicine drops to about 30°C, filter with gauze to obtain the filtrate, add 0.3g of chitosan oligosaccharide, 3g of grape seed extract, and 5g of probiotics , stir to dissolve it, and get 1 dose of liquid medicine. In the embodiment, the probiotic is Bifidobacterium lactis.

Embodiment 2

[0057] Weigh each raw material according to the following grams: Cornus officinalis 40g, bitter gourd 40g, Rehmannia glutinosa 10g, Panax notoginseng 15g, medlar 15g, Salvia miltiorrhiza 20g, Angelica 15g, Polygonatum 20g, Ophiopogon japonicus 5g, Asparagus 10g, Huanglian 15g, Zhilicorice 15g, lotus leaf 15g, Digupi 5g, hawthorn 10g, mulberry 10g, Eucommia 16g, burdock seed 10g, yam 20g. After removing the impurities, add 4000 ml of water, decoct with slow fire until the liquid medicine reaches 150 ml, the temperature of the medicine drops to about 32°C, filter with gauze to obtain the filtrate, add 0.2 g of chitosan oligosaccharide, 2 g of grape seed extract, and 15 g of probiotics , stir to dissolve it, and get 1 dose of liquid medicine. In the embodiment, the probiotics consist of Bifidobacterium lactis and Bifidobacterium bifidum with a mass ratio of 1:1.

Embodiment 3

[0059] Weigh each raw material according to the following grams: Cornus officinalis 47g, bitter gourd 48g, Rehmannia glutinosa 18g, Panax notoginseng 22g, medlar 16g, Salvia miltiorrhiza 21g, Angelica 22g, Polygonatum 21g, Ophiopogon japonicus 12g, Asparagus 14g, Coptis chinensis 23g, Zhigancao 16g , lotus leaf 23g, Digupi 9g, hawthorn 16g, mulberry 18g, Eucommia 19g, burdock seed 14g, yam 24g. After removing impurities, add 3000 ml of water, decoct with slow fire until the liquid medicine is 100 ml, the temperature of the medicine drops to about 30°C, filter with gauze to obtain the filtrate, add 0.28 g of chitosan oligosaccharide, 2.8 g of grape seed extract, and probiotics 5g, stir to dissolve, and obtain 1 dose of liquid medicine. In the embodiment, the probiotics are composed of Bifidobacterium breve, Bifidobacterium longum, Streptococcus thermophilus and Pediococcus lactis, with a mass ratio of 1:1.2:1:2.

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Abstract

The invention discloses a compound traditional Chinese medicine preparation as well as a preparation method and application thereof. The compound traditional Chinese medicine preparation comprises thefollowing raw materials of chitosan oligosaccharide, grape seed extract, fructus corni, balsam pear, radix rehmanniae preparata, radix notoginseng, fructus lycii, radix salviae miltiorrhizae, radix angelicae sinensis, rhizoma polygonati, radix ophiopogonis, radix asparagi, rhizoma coptidis, radix glycyrrhizae preparata, folium nelumbinis, cortex lycii radicis, fructus crataegi, mulberries, cortexeucommiae, fructus arctii, rhizoma dioscoreae and probiotics. The compound traditional Chinese medicine preparation is scientifically matched according to the theory of syndrome differentiation and treatment of traditional Chinese medicine, has the effects of reducing blood sugar, clearing away heat and toxic materials, nourishing yin and tonifying kidney and weakness of spleen and lung, enhancesthe function of a human body, is high in cure rate, short in treatment course, low in recurrence rate and less in toxic and side effects, and has a better effect on relieving diabetes and complications caused by diabetes. The defects of pure traditional Chinese medicine treatment and western medicine treatment are overcome, and the traditional Chinese medicine preparation is worthy of clinical application and popularization.

Description

technical field [0001] The invention mainly relates to the fields of biotechnology and medicine, in particular to a compound traditional Chinese medicine preparation, a preparation method and an application thereof. Background technique [0002] In recent years, the global incidence of diabetes has increased rapidly, and diabetes has become the third chronic disease that seriously threatens human health after tumors and cardiovascular diseases. At present, there are more than 120 million people with diabetes in the world, and the number of patients in my country ranks second in the world, reaching 20 million in 1994. According to the statistics of the International Diabetes Federation in 2017, 451 million adults worldwide suffer from diabetes, which is expected to increase to 693 million by 2045. In 2017, approximately 5 million adults worldwide died from diabetes, and global healthcare expenditures for people with diabetes were estimated at $850 billion. It has created a ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P3/10A61P37/04A61P1/16A61P13/12A61K31/722A61K31/702A61K35/744A61K35/745
CPCA61K31/702A61K31/722A61K35/744A61K35/745A61K36/232A61K36/258A61K36/28A61K36/40A61K36/42A61K36/46A61K36/484A61K36/537A61K36/605A61K36/62A61K36/718A61K36/734A61K36/804A61K36/815A61K36/87A61K36/8945A61K36/8965A61K36/8968A61K36/8969A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61P1/16A61P3/10A61P13/12A61P37/04A61K2300/00
Inventor 金黎明权春善侯熙彦赵晶张丽影许永斌张艳梅
Owner DALIAN NATIONALITIES UNIVERSITY
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