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Flexible electrode implantation system

A flexible electrode and rigid technology, which is applied in medical science, sensors, diagnostic recording/measurement, etc., can solve the problems of damage, limit the effective range of the electrode to the brain area, and the inability of the flexible electrode to disperse, so as to achieve good biocompatibility, Reduce the effect of motion artifacts

Pending Publication Date: 2020-11-27
INST OF SEMICONDUCTORS - CHINESE ACAD OF SCI
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  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

First, these methods require the use of invasive auxiliary implant tools, resulting in additional implant damage; second, the flexible electrodes cannot be spread out, which limits the effective range of the electrodes; third, the auxiliary implant materials affect the interface environment of the electrode recording point

Method used

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Embodiment Construction

[0024] The invention designs the fields of micro-nano processing technology and bioelectrical signal detection, specifically relates to the implantation method of flexible nerve electrodes, realizes autologous implantation of flexible electrodes, and extracts neuron signals with low damage and high quality.

[0025] Aiming at the problems of weak implantation strength, difficult operation, additional implantation damage and difficulty in determining the position of recording points in the existing flexible electrodes, the main purpose of the present invention is to provide a flexible electrode implantation model. The designed flexible electrodes are biocompatible and can reduce the immune response after the electrodes are implanted in brain tissue. At the same time, the implant guide instrument is used to realize the autologous implantation of the flexible electrode, and the implant guide platform is fixed on the brain plane of the craniotomy to prevent the auxiliary implant to...

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Abstract

The invention provides a flexible electrode implantation system. The flexible electrode implantation system comprises a foldable flexible electrode and an implantation guiding instrument, wherein thefoldable flexible electrode is used for extracting the discharge activity of neurons; and the implantation guiding instrument comprises an implantation guiding platform and an implantation guiding column and is used for sending the flexible electrode into a target brain region. The flexible electrode implantation system adopts an implantation mode of combining the flexible electrode with an implantation tool. The prepared flexible electrode has good biocompatibility, and does not cause excessive signal acquisition of astrocytes and microglial cells on nerve cells; and meanwhile, the electrodehas enough flexibility to move along with the movement of brain tissues, so that the generation of motion artifacts is reduced. The prepared implantation guiding instrument is used for in-vitro auxiliary flexible electrode implantation, the implantation depth of the flexible electrode can be controlled, additional implantation damage cannot be caused, and the interface environment of electrode recording points cannot be influenced.

Description

technical field [0001] The invention relates to the fields of micro-nano processing technology and bioelectrical signal detection, in particular to a flexible electrode implantation system. Background technique [0002] The 21st century is the era of brain science. The study of cognitive activities such as human brain language, memory, thinking, learning and attention is one of the mainstream directions of contemporary scientific development. Neural electrodes provide a way to clarify the neural mechanisms of various brain cognitive activities. important tool. Traditional nerve microelectrodes are hard, which causes mechanical mismatch between nerve electrodes and nerve tissue, causing nerve tissue damage and continuous immune inflammatory response. The development of polymer materials makes flexible electrodes one of the mainstream directions of nerve electrodes. The flexible electrode made of low Young's modulus material can effectively improve the mechanical mismatch of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/0478A61B5/00
CPCA61B5/6868
Inventor 裴为华魏春蓉
Owner INST OF SEMICONDUCTORS - CHINESE ACAD OF SCI
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