Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Film coating liquid for halogenated butyl rubber plug, film coated rubber plug, and preparation methods and applications of film coating liquid and film coated rubber plug

A technology of halogenated butyl rubber and film coating liquid, which is applied in the directions of application, sealing with stopper, coating, etc., can solve the problems such as the halogenated butyl rubber stopper cannot meet the packaging requirements, restrict the development of traditional Chinese medicine injection, and increase the cost of medicines, etc. Achieve good sealing performance and peel strength, increase elasticity, and extend the effect of expiration date

Inactive Publication Date: 2020-11-20
JIANGSU RUNDE MEDICAL MATERIALS
View PDF7 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In our country, the packaging of unique traditional Chinese medicine injections often uses foreign rubber stoppers or film-coated rubber stoppers, which leads to a substantial increase in drug costs and is not conducive to the development of the industry.
[0005] In summary, the domestic halogenated butyl rubber stoppers cannot meet the packaging requirements of small-dose injections and Chinese medicine injections in my country, which limits the application of rubber stoppers in related fields. At the same time, to a certain extent, it also limits the use of Chinese medicine injections in my country develop

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Film coating liquid for halogenated butyl rubber plug, film coated rubber plug, and preparation methods and applications of film coating liquid and film coated rubber plug
  • Film coating liquid for halogenated butyl rubber plug, film coated rubber plug, and preparation methods and applications of film coating liquid and film coated rubber plug
  • Film coating liquid for halogenated butyl rubber plug, film coated rubber plug, and preparation methods and applications of film coating liquid and film coated rubber plug

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0044] The preparation method of the coating liquid provided by the invention has simple process, convenient operation, can be completed without expensive reaction equipment, and is suitable for popularization and application.

[0045] Preferably, the auxiliary crosslinking agent includes potassium persulfate; the anticoagulant includes succinic acid and / or potassium nitrate.

[0046] In the present invention, the meaning of "and / or" means that succinic acid can be selected as the anticoagulant alone, potassium nitrate can also be selected as the anticoagulant alone, and succinic acid and potassium nitrate can also be selected as the anticoagulant at the same time.

[0047] Optionally, the added amount of the potassium persulfate is 0.3% of the weight of the solvent; the added amount of the succinic acid is 0.2% of the weight of the solvent; the added amount of the potassium nitrate is 0.2% of the weight of the solvent.

[0048] Preferably, the pressure during mixing is 0.03-0...

Embodiment 1

[0062] This embodiment provides a coating solution for halogenated butyl rubber stoppers, including:

[0063] 30 parts of aryl siloxane, 100 parts of polytetrafluoroethylene and 300 parts of solvent.

[0064] Its preparation method includes:

[0065] After mixing the formulated amount of aryl siloxane, polytetrafluoroethylene, solvent and potassium persulfate, then adding succinic acid and potassium nitrate to react to obtain the coating solution for halogenated butyl rubber stopper;

[0066] Wherein, the solvent is water;

[0067] The add-on of described potassium persulfate is 0.3% of solvent weight; The add-on of described succinic acid is 0.2% of solvent weight; The add-on of described potassium nitrate is 0.2% of solvent weight;

[0068] The pressure during mixing is 0.05Mpa, the temperature is 75°C, and the time is 2 hours;

[0069] The temperature during the reaction was 100° C., and the time was 8 hours.

Embodiment 2

[0071] This embodiment provides a kind of coating solution for halogenated butyl rubber stopper, and the difference with embodiment 1 is:

[0072] 40 parts of aryl siloxane, 80 parts of polytetrafluoroethylene and 500 parts of solvent.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a film coating liquid for a halogenated butyl rubber plug, a film coated rubber plug, and preparation methods and applications of the film coating liquid and the film coated rubber plug, and relates to the technical field of medical rubber accessories, and the film coating liquid for the halogenated butyl rubber plug provided by the invention is simple in formula, and only comprises aryl siloxane, polytetrafluoroethylene and corresponding solvents. After polytetrafluoroethylene is formed into a film, a vulcanizing agent and various other additives in the halogenated butyl rubber plug can be effectively prevented from being separated out, and pollution to stored products is avoided. Meanwhile, aryl siloxane is matched, so that the elasticity of the halogenated butyl rubber plug can be greatly improved, the halogenated butyl rubber plug has better self-sealing performance, the quality of a preserved product is guaranteed, and the valid period is prolonged.

Description

technical field [0001] The invention relates to the technical field of medical rubber accessories, in particular to a coating solution for halogenated butyl rubber stoppers, a coating rubber stopper and their preparation methods and applications. Background technique [0002] Halogenated butyl rubber was used abroad in the 1950s and 1960s to manufacture medical bottle stoppers because of its air permeability, low moisture permeability, good heat aging resistance, and high cleanliness. In the 1990s, my country began to butyl stoppers for medical use. After 20 years of development, domestic halogenated butyl rubber stoppers can meet the packaging requirements of most drugs, but for some small-dose, sensitive drugs, the compatibility between rubber stoppers and drugs fluctuates greatly, and the performance is unstable. The application of domestic halogenated butyl rubber stoppers in small doses and highly sensitive drugs. [0003] On the packaging of medicines for injection, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C09D127/18C09D7/63C08J7/04A61J1/14B65D39/00C08L23/28
CPCA61J1/14B65D39/00C08J7/04C08J2323/28C08J2427/18C09D127/18C09D7/63C08K5/54
Inventor 司俊杰朱善本
Owner JIANGSU RUNDE MEDICAL MATERIALS
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com