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Antibacterial gel for gynecology and preparation method of antibacterial gel

A gel and gynecological technology, applied in the field of medicine, can solve the problems of long-term cure and easy recurrence of inflammation, and achieve the effect of improving healing speed, definite curative effect, and promoting skin wound healing

Inactive Publication Date: 2020-10-30
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During treatment, symptoms usually improve or disappear quickly, but inflammation tends to recur and persist for a long time

Method used

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  • Antibacterial gel for gynecology and preparation method of antibacterial gel
  • Antibacterial gel for gynecology and preparation method of antibacterial gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] An antibacterial gel for gynecology, prepared from the following raw materials by weight percentage: cecropin antibacterial peptide B1%, Gastrodia elata polypeptide 5%, luteolin 2%, carbomer 10%, propylene glycol 6%, tocopherol 5%, sodium hyaluronate 1%, menthol 0.5%, an appropriate amount of pH regulator, and the balance is purified water.

[0031] The preparation method of the antibacterial gel for gynecology comprises the following steps:

[0032] (1) Mix cecropin antimicrobial peptide B, Gastrodia elata polypeptide and propylene glycol evenly to obtain an antimicrobial peptide solution;

[0033] (2) Put carbomer and purified water into the reactor, heat appropriately, stir and dissolve until mixed evenly, and obtain matrix solution;

[0034] (3) After naturally cooling to room temperature, pour the antimicrobial peptide solution into the matrix solution, stir evenly, then add luteolin, tocopherol, sodium hyaluronate and menthol in sequence, stir and dissolve until ...

Embodiment 2

[0037] An antibacterial gel for gynecology, prepared from the following raw materials by weight percentage: 5% cecropin antibacterial peptide B, 1% Gastrodia elata polypeptide, 4% luteolin, 30% carboxymethyl cellulose, polyethylene glycol -2002%, 1% tocopherol, 3% sodium hyaluronate, 2% menthol, appropriate amount of pH regulator, and the balance is purified water.

[0038] The preparation method of the antibacterial gel for gynecology comprises the following steps:

[0039] (1) Mix cecropin antimicrobial peptide B, Gastrodia elata polypeptide and polyethylene glycol-200 evenly to obtain an antimicrobial peptide solution;

[0040] (2) Put carboxymethyl cellulose and purified water into the reactor, heat appropriately, stir and dissolve until mixed evenly, and obtain matrix solution;

[0041] (3) After naturally cooling to room temperature, pour the antimicrobial peptide solution into the matrix solution, stir evenly, then add luteolin, tocopherol, sodium hyaluronate and menthol...

Embodiment 3

[0044] An antibacterial gel for gynecology, prepared from the following raw materials by weight percentage: cecropin antibacterial peptide B 3%, Gastrodia elata polypeptide 3%, luteolin 3%, hydroxypropyl methylcellulose 20%, glycerin 4% , 3% tocopherol, 2% sodium hyaluronate, 0.8% menthol, an appropriate amount of pH regulator, and the balance is purified water.

[0045] The preparation method of the antibacterial gel for gynecology comprises the following steps:

[0046] (1) Mix cecropin antimicrobial peptide B, Gastrodia elata polypeptide and glycerin evenly to obtain an antimicrobial peptide solution;

[0047] (2) putting hydroxypropylmethylcellulose and purified water into the reactor, heating appropriately, stirring and dissolving until mixed evenly, and obtaining a matrix solution;

[0048] (3) After naturally cooling to room temperature, pour the antimicrobial peptide solution into the matrix solution, stir evenly, then add luteolin, tocopherol, sodium hyaluronate and ...

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Abstract

The invention discloses antibacterial gel for gynecology and a preparation method thereof. The antibacterial gel is prepared from the following raw materials in percentage by weight: 1-5% of cecropinantibacterial peptide, 1-5% of gastrodia elata polypeptide, 1-5% of luteolin, 10-30% of a thickener, 2-6% of a wetting agent, 1-5% of tocopherol, 1-3% of sodium hyaluronate, 0.5-2% of menthol, a proper amount of a pH regulator and the balance of purified water. The antibacterial gel for the gynecology uses cecropin B and gastrodia elata polypeptide as antibacterial peptide active ingredients, which has a synergistic antibacterial effect, and can treat gynecological diseases such as cervical erosion, vaginitis and pelvic inflammation. The antibacterial gel disclosed by the invention is non-irritant to vaginal mucosa cells, high in safety, and excellent in stability and easy to absorb by a human body, and after the gynecological antibacterial gel is used, the skin of the private parts of women can be moisturized, fresh and healthy.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an antibacterial gel used in gynecology and a preparation method thereof. Background technique [0002] Gynecological diseases are common diseases among women. Unbalanced flora, damaged mucous membranes, and microenvironmental damage can all lead to the occurrence of gynecological diseases, such as trichomonal vaginitis and bacterial vaginosis, which bring great harm to women's life and work. Impact. According to reports, about 87% of adult women in the world have been infected with gynecological inflammation in varying degrees. Gynecological vaginitis is a common disease in gynecology, accounting for 1 / 3 of gynecological outpatients. It is usually caused by inflammation of subvaginal mucosa and submucosal connective tissue. Vaginitis has a high prevalence rate, easy recurrence, and many complications. It has been confirmed that it is related to infertility, premat...

Claims

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Application Information

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IPC IPC(8): A61K38/17A61K9/06A61K47/10A61K47/22A61K47/36A61P15/00A61P15/02A61P31/04A61P31/10A61P33/02A61K31/352A61K38/01
CPCA61K9/0034A61K9/06A61K31/352A61K38/011A61K38/1729A61K47/10A61K47/22A61K47/36A61P15/00A61P15/02A61P31/04A61P31/10A61P33/02A61K2300/00
Inventor 沈文娟张杨韩梅汪娜刘学伟
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE
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