ASL image processing method for severe stenosis/occlusion of artery in unilateral brain

Abstract

The invention discloses an ASL image processing method for severe stenosis / occlusion of the artery in unilateral brain. The method can display cerebral perfusion condition of severe stenosis / occlusionof the artery of the unilateral brain in a non-invasive, contrast agent-free, high-repeatability and high-resolution manner, and can accurately evaluate cerebral hemodynamics. The method comprises the following steps: (1) collecting a plurality of cases of patients with severe stenosis / occlusion of artery in the unilateral brain, and dividing the cases into a symptomatic group and an asymptomaticgroup according to whether clinical symptoms exist or not; (2) carrying out magnetic resonance scanning by using an American GE 3.0T magnetic resonance scanner, and carrying out magnetic resonance imaging on patients with severe stenosis / occlusion of the artery in the unilateral brain by adopting a 3D pCASL technology with three PLDs; (3) performing ASL data post-processing by using a CereFlow software of an Anying Science and Technology Company; and (4) comparing the differences of the cerebral perfusion parameters of the artery in the affected-side brain of the symptomatic group and the non-symptomatic group by adopting an independent sample t test, and respectively comparing the differences of two groups of cerebral perfusion parameters of the artery in the affected-side brain and theartery in the healthy-side brain by adopting a paired sample t test.

Description

technical field [0001] The present invention relates to the technical field of medical image processing, in particular to an ASL image processing method for severe stenosis / occlusion of unilateral middle cerebral artery, which is mainly used to display cerebral blood flow, arterial transit time and arterial brain in the blood supply area of ​​middle cerebral artery. Blood volume, thus used to assess cerebral perfusion in patients with severe unilateral middle cerebral artery stenosis / occlusion. Background technique [0002] Arterial spin labeling (ASL) is a non-invasive magnetic resonance imaging technique for detecting brain perfusion. Subtraction analysis was performed on the images before and after labeling to obtain qualitative and quantitative maps of cerebral blood flow (CBF). The image acquisition and processing process of ASL technology generally includes the following steps: (1) Inverting the pulse to mark the water protons in the arterial blood. (2) When the mark...

AI Technical Summary

Problems solved by technology

For patients with cerebrovascular disease, a single PLD is often unable to accurately assess cerebral blood flow (CBF) due to hemodynamic changes

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