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Method for improving anticancer immunoenhancement efficacy of Baolingsu extracted solution

A technology of immune enhancement and extract, which is applied in the field of marine biology, can solve the problems that Baolingsu is difficult to achieve large-scale application, and achieve the goal of improving the anti-cancer immune enhancement function, improving the anti-cancer immune enhancement effect, and improving the anti-cancer health care effect Effect

Inactive Publication Date: 2020-08-07
梁志勇
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, with the discovery of the anticancer activity of Baolingsu, the research and application of Baolingsu have been favored more and more. In terms of application, it is difficult to achieve large-scale application, and the creation and application of key technologies are urgently needed

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0037] A method for improving the anti-cancer immune enhancement effect of Baolingsu extract, the specific process steps comprising:

[0038] (1) Cleaning: Clean the fresh abalone with tap water, then wash it with natural mineral water or purified water and drain it for later use;

[0039] (2) Homogenization: Add the abalone obtained in step (1) into a high-speed homogenizer, add natural mineral water or purified water, and perform high-speed homogenization until all can pass through a 2mm aperture circular sieve;

[0040] (3) Sterilization: Sterilize the homogenized abalone through a high-pressure steamer, and cool it for later use;

[0041] (4) Compound enzymolysis: add a compound enzyme preparation with a mass ratio of 2% to the sterilized slurry, and stir the enzymolysis at 40-60°C for 30 minutes; the compound enzyme preparation is protease, non-starch polysaccharide enzyme and fruit The mixture of glue enzymes, its mass ratio is 2:1:2;

[0042] (5) Aerobic fermentation:...

Embodiment 2

[0050] A method for improving the anti-cancer immune enhancement effect of Baolingsu extract, the specific process steps comprising:

[0051] (1) Cleaning: Clean the fresh abalone with tap water, then wash it with natural mineral water or purified water and drain it for later use;

[0052] (2) Homogenization: Add the abalone obtained in step (1) into a high-speed homogenizer, add natural mineral water or purified water, and perform high-speed homogenization until all can pass through a 2mm aperture circular sieve;

[0053] (3) Sterilization: Sterilize the homogenized abalone through a high-pressure steamer, and cool it for later use;

[0054] (4) Compound enzymolysis: add 2% compound enzyme preparation by mass ratio and 2% dextran in enzymolysis solution to the sterilized slurry, stir and enzymolyze at 40-60°C for 30 minutes; The compound enzyme preparation is a mixture of protease, non-starch polysaccharide enzyme and pectinase, and its mass ratio is 2:1:2;

[0055] (5) Aer...

Embodiment 3

[0063] A method for improving the anti-cancer immune enhancement effect of Baolingsu extract, the specific process steps comprising:

[0064] (1) Cleaning: Clean the fresh abalone with tap water, then wash it with natural mineral water or purified water and drain it for later use;

[0065] (2) Homogenization: Add the abalone obtained in step (1) into a high-speed homogenizer, add natural mineral water or purified water, and perform high-speed homogenization until all can pass through a 2mm aperture circular sieve;

[0066] (3) Sterilization: Sterilize the homogenized abalone through a high-pressure steamer, and cool it for later use;

[0067] (4) Compound enzymolysis: add 2% compound enzyme preparation and 3% dextran to the sterilized slurry, stir and enzymolyze at 40-60°C for 30 minutes; The compound enzyme preparation is a mixture of protease, non-starch polysaccharide enzyme and pectinase, and its mass ratio is 2:1:2;

[0068] (5) Aerobic fermentation: add a compound micr...

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Abstract

The invention belongs to the field of marine biotechnology, and discloses a method for improving the anticancer immunoenhancement efficacy of a Baolingsu extracted solution. Abalone is used as the rawmaterial, a modern biological separation technology, a biological enzymolysis technology, a mixed bacteria microbial fermentation technology, and an ethanol precipitation and resin adsorption technology are integrated to research and develop the Baolingsu biological product with high antitumor immunoenhancement efficacy, wherein mixed aerobic fermentation strains mainly comprise bacillus subtilis, bacillus licheniformis and bacillus psychrosaccharolyticus, and glucan is added in the enzymolysis process, so that the anti-cancer immunoenhancement efficacy of the Baolingsu extracted solution isremarkably improved. According to the process technology, the extraction rate of Baolingsu is high, and the obtained Baolingsu biological product is high in anti-cancer capability and convenient for industrial large-scale production.

Description

technical field [0001] The invention relates to a method for improving the anti-cancer and immune-enhancing effect of Baolingsu extract, in particular to a Baolingsu biological product with high anti-cancer and health-care effects prepared by using abalone as a raw material through microbial cooperative fermentation, and belongs to the technical field of marine biology. Background technique [0002] Abalone, known as flatfish in ancient times, also known as mirror fish, nine-hole snail, bright eye fish, general cap, is a kind of marine mollusk, which belongs to the single-shelled marine shellfish of the gastropod family Abalone, and is also a traditional Chinese food. , known as flatfish in ancient times, is one of the delicacies of mountains and seas. It is known as "one bite of abalone, one bite of gold". "Diet Therapy Materia Medica" records that abalone enters the liver to clear blood stasis, enters the intestines to cleanse dirt, and does not hurt vitality. Strengtheni...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/618A61P35/00A61P37/04A23L33/10
CPCA23L33/10A23V2002/00A61K35/618A61P35/00A61P37/04A23V2200/308A23V2200/324A23V2250/2042
Inventor 梁志勇杨庆利马迪宋仁芳
Owner 梁志勇
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