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A kind of preparation method and assembly method of miniature magnetron robot, inner core and thin film

A robot and miniature technology, applied in medical science, surgery, etc., can solve the problems of expensive treatment, liver organ damage, long treatment cycle, etc., and achieve good therapeutic effect, good biocompatibility, and simple operation

Active Publication Date: 2021-04-23
BEIJING INST OF NANOENERGY & NANOSYST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] At present, there are three main treatment methods for cholelithiasis: one is surgical treatment, including cholecystectomy or gallbladder stone removal. Although this method can effectively treat cholelithiasis, it is harmful to the human body. , patients will experience symptoms such as indigestion, diarrhea, and abdominal distension, and there is also a risk of postoperative infection; the second is extracorporeal ultrasonic lithotripsy, which has high technical content, but is relatively risky, and may cause damage to other organs such as the liver, and Little effect, there is still about 11.2% stone recurrence rate, the treatment cost is expensive, and the treatment scope is strict; the third is the drug stone-dissolving method, which mainly uses ursodeoxycholic acid for stone-dissolving treatment, and the treatment period of this method is long, and The effect is limited, the drug has certain side effects, and it is often combined with other therapies in clinical practice

Method used

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  • A kind of preparation method and assembly method of miniature magnetron robot, inner core and thin film
  • A kind of preparation method and assembly method of miniature magnetron robot, inner core and thin film
  • A kind of preparation method and assembly method of miniature magnetron robot, inner core and thin film

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preparation example Construction

[0058] The present disclosure also proposes a method such as figure 2 The preparation method of the magnetic composite spherical core 210 shown includes the following steps.

[0059] S110, uniformly mix the first magnetic material and the prefabricated liquid of the flexible material according to a first preset ratio to obtain a mixed material.

[0060] Preferably, the first preset ratio of the first magnetic material to the flexible material is 1:2.

[0061] Optionally, the first magnetic material is a plurality of magnetic particles, the diameter of which is not greater than 300 mesh.

[0062] S120, inject the mixed material into two hollow hemispherical moulds.

[0063] S150, demolding the mixed liquid after curing to obtain two hemispheres of the same size.

[0064] S140, bonding the two hemispheres to obtain a magnetic composite spherical core 210 .

[0065] Optionally, when the magnetic composite spherical inner core 210 is spherical, the mold for the magnetic compo...

Embodiment 1

[0096] In this embodiment, the method of using the micro-magnetic-controlled robot 100 is described in detail.

[0097] Patients fasted for 12 hours before lithotripsy to ensure an empty stomach. Before lithotripsy, the patient takes orally one or more micro-magnetic-controlled robots 100, and uses a B-ultrasound instrument to monitor the position of the micro-magnetic-controlled robots 100 after entering the human body. Using an external permanent magnet or a multi-degree-of-freedom magnetic control system to generate a guiding magnetic field, the micro-magnetic-controlled robot 100 is guided from the patient's stomach 402 to the gallbladder through the guiding magnetic field. When the micro-magnetic-controlled robot 100 reaches the gallbladder, the pulsed magnetic field generator 401 is used to generate a magnetic field with a magnetic field strength of about 2700Gs, and the frequency of magnetic field generation is 80 times per minute, so that the micro-magnetic-controlled ...

Embodiment 2

[0101] In this embodiment, the assembly method using the micro magnetic control robot 100 is described in detail.

[0102] The flexible spiny functional film 220 taken out from the mold of the flexible spiny functional film 220 has a relatively large area, and a rectangular film with a size of 12.8×2mm and two pieces with a radius of 2.3mm and a center angle of 320° are cut from it. Fan-shaped film, the rectangular film is bonded to the magnetic composite spherical core 210 with a radius of 4mm to form a barrel, and the two fan-shaped films are respectively rolled into two conical sticks on both sides of the barrel surrounded by the rectangular film , after the bonding is completed, the micro-magnetic-controlled robot 100 is obtained. Since the micro-magnetic-controlled robot 100 is very small, the micro-magnetic-controlled robot 100 is approximately regarded as a sphere.

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Abstract

A miniature magnetically controlled robot, including a magnetic composite spherical inner core, which can realize periodic reciprocating vibration under the action of a pulsed magnetic field, and a flexible spiny functional film, which is coated and bonded to the magnetic composite spherical inner core On the outer surface of the flexible spiny functional film, there are multiple spiny structures distributed on the surface. The miniature magnetically controlled robot provided by the present disclosure can realize non-invasive targeted treatment of diseases such as gallstones, has obvious therapeutic effect, high safety, and has broad application prospects. The disclosure also provides the preparation method of the flexible spiny functional film, the magnetic composite spherical inner core and the miniature magnetron robot, the preparation method is simple and the production cost is low.

Description

technical field [0001] The present disclosure relates to the technical field of medical equipment, in particular to a micro-magnetic-controlled robot, a preparation method and an assembly method of an inner core and a thin film. Background technique [0002] Cholelithiasis is a common and frequently-occurring disease worldwide. Epidemiological surveys show that the incidence of gallstone disease in my country has reached about 10% of the total population. [0003] At present, there are three main treatment methods for cholelithiasis: one is surgical treatment, including cholecystectomy or gallbladder stone removal. Although this method can effectively treat cholelithiasis, it is harmful to the human body. , patients will experience symptoms such as indigestion, diarrhea, and abdominal distension, and there is also a risk of postoperative infection; the second is extracorporeal ultrasonic lithotripsy, which has high technical content, but is relatively risky, and may cause d...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B17/22
CPCA61B17/22012A61B2017/00526A61B2017/00876
Inventor 杨亚徐林武鹤婷
Owner BEIJING INST OF NANOENERGY & NANOSYST
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