Glucoraphanin composition and application thereof

一种萝卜硫苷、组合物的技术，应用在制备用于癌症化学预防和治疗的产品领域，能够解决易失去活性、β-硫苷酶不稳定性、苛刻等问题

Active Publication Date: 2020-07-17
SHENZHEN F&S BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, as an enzyme, β-sulfatase is inherently unstable and easily loses activity at room temperature
Therefore, the conditions required for enzyme extraction and corresponding storage and transportation are relatively harsh, resulting in high cost of enzyme-containing products and inconvenient storage and transportation, making it difficult to be widely used

Method used

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  • Glucoraphanin composition and application thereof
  • Glucoraphanin composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Preparation of glucoraphanin-rich broccoli sprout extract composition (composition A)

[0046] (1) Mixing: 1800g of broccoli sprout extract (containing 16.0% glucoraphanin) was evenly mixed with 200g of fructooligosaccharides to obtain 2kg of broccoli sprout extract composition, wherein glucoraphanin accounted for 14.4%.

[0047] (2) Bagged product: the above-mentioned broccoli sprout extract composition rich in glucoraphanin is divided into small bags according to the weight of each bag of 2g to obtain a powder product.

Embodiment 2

[0049] Preparation of Broccoli Sprout Extract Composition (Composition B) Rich in Glucoraphanin

[0050] (1) Mixing: 2kg of broccoli sprout extract (containing glucoraphanin 16.0%) is mixed evenly with 1kg of xylooligosaccharides to obtain 3kg of broccoli sprout extract composition rich in glucoraphanin, wherein sulforaphane Glycosides accounted for 10.7%.

[0051] (2) Bagged product: the above-mentioned glucoraphanin-rich broccoli sprout extract composition is divided into small bags according to the weight of 2g per bag to obtain a powder product, wherein glucoraphanin accounts for 10.7%.

Embodiment 3

[0053] Preparation of the composition (composition C) of glucoraphanin-rich broccoli sprout powder and broccoli sprout extract

[0054] (1) Mixing: 200g broccoli sprout powder extract (containing glucoraphanin 16%), 800g broccoli sprout powder (containing glucoraphanin 5%), 250g chitosan oligosaccharide, 250g fructooligosaccharide, 250g low Xylan, 250g of isomaltooligosaccharide and 10g of ascorbic acid were evenly mixed to obtain 2.01kg of glucoraphanin-rich broccoli sprout powder and broccoli sprout extract composition, wherein glucoraphanin accounted for 3.58%.

[0055] (2) Bagged product: the above-mentioned glucoraphanin-rich broccoli powder and broccoli sprout extract composition are divided into small bags according to the weight of 2g per bag to obtain powder products, wherein glucoraphanin Accounting for 3.58%.

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Abstract

The invention discloses a glucoraphanin composition and application thereof. The invention provides a composition comprising glucoraphanin and a functional oligosaccharide. The invention also relatesto a use of the composition in preparation of a product for chemoprophylaxis and / or treatment of cancer.

Description

technical field [0001] The invention provides a composition comprising glucoraphanin and functional oligosaccharides. The invention also relates to the use of said composition in the manufacture of products for cancer chemoprevention and treatment. Background technique [0002] According to the 2014 annual report of the World Health Organization, cancer is the main cause of global morbidity and death, poses a huge threat to people's life and health, and brings a heavy economic burden to social development. In the long process of fighting cancer, people put forward the concept of cancer chemoprevention in 1976, which refers to the strategy of using natural or synthetic chemical substances to prevent, slow down or reverse the occurrence and development of cancer. Sulforaphane (SFN), also known as sulforaphane, chemically named 1-isothiocyanate-4-methanesulfonylbutane, belongs to the class of isothiocyanates, and is the strongest substance found in vegetables so far. anticanc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7028A61K31/702A23L33/105A23L33/10A23L33/125A61P35/00
CPCA61K31/702A61K31/7028A23V2002/00A61P35/00A23L33/105A23L33/10A23L33/125A61K2300/00A23V2200/32A23V2200/30A23V2250/21A23V2200/308A23V2250/28A23V2250/708A23V2250/5112A23V2250/511A23V2250/5062
Inventor 李晓龙朱志鹏罗永平李欣
Owner SHENZHEN F&S BIO TECH
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