Preparation method of urinary calculus-removing choleretic granules

A technology for removing stones and promoting gallbladder and granules, applied in the field of traditional Chinese medicine, can solve the problems of poor drying granulation effect, poor forming of traditional Chinese medicine granules, waste of medicinal materials, etc., and achieves the effects of good forming, high powdering rate, and avoiding sticking to the wall.

Inactive Publication Date: 2020-07-10
江西纳弗堂制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, the Chinese patent medicine granules for removing stones and promoting gallbladder do not need to be decocted and taken, and are convenient and quick. However, the dry granulation process used in the existing preparation methods has sticky wall phenomenon. On the one hand, the medicinal materials are wasted, and on the other hand, they are dried and granulated. The effect is not good, making the formation of Chinese medicine granules poor

Method used

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  • Preparation method of urinary calculus-removing choleretic granules
  • Preparation method of urinary calculus-removing choleretic granules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A Paishi Lidan granule, which comprises the following raw materials in parts by weight: raw medicinal materials and solvents, wherein the raw medicinal materials include 5 parts of Bupleuri, 1 part of woody incense, 15 parts of turmeric, 12 parts of Desmodium, 12 parts capillary, 5 parts baicalin, 3 parts Wulingzhi, 4 parts Puhuang, 2 parts Chuanlianzi, 13 parts red peony, 11 parts mallow, 12 parts talcum powder, 10 parts rhubarb, 3 parts Citrus aurantium , 8 parts of radish seeds, 5 parts of Atractylodes macrocephala, 13 parts of coix seed, 1 part of gallinaceous gold, 2 parts of licorice, 5 parts of Shiwei, 1 part of gentian and 1 part of corn silk.

[0027] A preparation method of Paishi Lidan Granules, comprising the following steps:

[0028] Step 1: heating and refluxing the original medicinal material in a solvent to extract three times, combining the three times of extracting liquid to obtain the extracting liquid; using water as the solvent, that is, using 6, 5,...

Embodiment 2

[0034] A Paishi Lidan granule, which comprises the following raw materials in parts by weight: raw medicinal materials and solvents, wherein the raw medicinal materials include 10 parts of Bupleuri, 8 parts of woody incense, 15 parts of turmeric, 17 parts of Desmodium, 11 parts capillary, 7 parts baicalin, 5 parts Wulingzhi, 5 parts Puhuang, 7 parts Chuanlianzi, 13 parts red peony, 11 parts mallow seed, 12 parts talcum powder, 11 parts rhubarb, 5 parts Citrus aurantium , 9 parts of radish, 6 parts of Atractylodes macrocephala, 15 parts of coix seed, 6 parts of gallinaceous gold, 7 parts of licorice, 6 parts of Shiwei, 2 parts of gentian and 5 parts of corn silk.

[0035] A preparation method of Paishi Lidan Granules, comprising the following steps:

[0036] Step 1: heating and refluxing the original medicinal material in a solvent for three times, combining the three times of extracting liquid to obtain the extracting liquid; that is, using 6, 5, and 5 times the amount of wate...

Embodiment 3

[0042] A Paishi Lidan granule, which comprises the following raw materials in parts by weight: raw medicinal materials and solvents, wherein the raw medicinal materials include 9 parts of Bupleuri, 3 parts of woody incense, 12 parts of turmeric, 30 parts of Desmodium, 11 parts capillary, 6 parts baicalensis, 7 parts Wulingzhi, 8 parts Puhuang, 6 parts Chuanlianzi, 13 parts red peony, 15 parts mallow seed, 12 parts talcum powder, 11 parts rhubarb, 6 parts Citrus aurantium , 10 parts of radish seed, 6 parts of Atractylodes macrocephala, 15 parts of coix seed, 6 parts of gallinaceous gold, 5 parts of licorice, 7 parts of Shiwei, 2 parts of gentian and 9 parts of corn silk.

[0043] A preparation method of Paishi Lidan Granules, comprising the following steps:

[0044] Step 1: heating and refluxing the original medicinal material in a solvent for three times, combining the three times of extracting liquid to obtain the extracting liquid; that is, using 6, 5, and 5 times the amount...

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Abstract

The invention discloses a preparation method of urinary calculus-removing choleretic granules. According to the preparation method of the urinary calculus-removing choleretic granules, the urinary calculus-removing choleretic granules comprise original medicinal materials and a solvent. The preparation method includes the following steps: Step 1, performing heating reflux extraction on the original medicinal materials in the solvent at least three times, and merging the three extraction liquids so as to obtain an extract; Step 2, filtering the extract obtained in the Step 1, and concentratingthe filtered extract so as to obtain clear ointment; and Step 3, performing granulation and forming on the clear ointment obtained in the Step 2 so as to prepare the urinary calculus-removing choleretic granules. The preparation method has the advantages that active ingredients in the original medicinal materials can be extracted effectively through multiple times of extraction so that the accuracy of the formula ratio is ensured; moreover, the temperature of an air outlet is reduced through appropriate increase of the temperature of inlet air and acceleration of drying at the same time, and / or sticking, caused by softening of drug particles, to the wall is prevented effectively through addition of an auxiliary material with a high softening point to auxiliary materials, the powdering rateis high, and the prepared particles can be formed well.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a preparation method of Paishi Lidan Granules. Background technique [0002] Gallstone disease is a common, multiple digestive system disease, is one of the common acute abdomen. The prevalence of gallstone disease in my country is on the rise rapidly, reaching 10% in some areas, which is close to the 10-15% incidence level of gallstone disease in developed countries in the world. [0003] Cholelithiasis is currently treated mainly by surgery, especially laparoscopic surgery, but the recurrence rate is high, and the difficulty and risk of re-operation will increase. Therefore, there is a view that surgery cannot solve the problem of gallbladder stones, and patients have fear of surgery. The curative effect of Western medicine treatment of gallstone disease is not good enough, the side effect is big, and the price is expensive, so it is more and more necessary to adopt...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/16A61P1/16A61K33/12A61K35/24A61K35/57
CPCA61K9/1611A61K9/1652A61K33/12A61K35/24A61K35/57A61K36/12A61K36/185A61K36/233A61K36/282A61K36/284A61K36/285A61K36/31A61K36/484A61K36/515A61K36/53A61K36/539A61K36/58A61K36/65A61K36/708A61K36/71A61K36/752A61K36/88A61K36/899A61K36/8994A61K36/9066A61K2236/331A61K2236/39A61K2236/51A61P1/16A61K2300/00
Inventor 郭志武熊欠兴王志荣李小丽
Owner 江西纳弗堂制药有限公司
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