Process and device for producing glycine by alcohol phase method

A production process, glycine technology, applied in chemical instruments and methods, preparation of organic compounds, organic chemistry, etc., can solve the problems of high production cost, high equipment and pipeline requirements, high equipment operation and maintenance costs, and achieve production cost reduction , significant economic benefits, and significant environmental benefits

Pending Publication Date: 2020-07-03
HUBEI TAISHENG CHEM
View PDF5 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the domestic industrial production process of glycine still adopts the traditional ammonolysis method of chloroacetic acid with water as the solvent. This method has the following problems: (1) High production cost
The catalyst urotropine cannot be recovered; 1 ton of glycine needs to consume about 6-7 tons of steam; when recovering low value-added ammonium chloride, the requirements for equipment and pipelines are high, the frequency of maintenance is high, and the cost of equipment operation and maintenance is relatively high
(2) Low yield, difficult to break through 85%
The system in the aqueous phase is highly alkaline, and the conversion rate of chloroacetic acid into glycine is low, and about 15% of chloroacetic acid is hydrolyzed to produce glycolic acid; when high temperature ammonia is insufficient, it is easy to produce iminodiacetic acid [NH(CH 2 COOH) 2 ] and aminotriacetic acid [N(CH 2 COOH) 3 ] and other by-products
(3) Environmental risks cannot be completely eliminated
There are defects in this method: (1) The output of the by-product ammonium chloride obtained each time is limited, which affects the output of glycine single-pot production. In order to obtain more ammonium chloride in a single-pot, the organic solvent needs to be refrigerated and cooled, and the energy consumption is relatively low. Big

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Process and device for producing glycine by alcohol phase method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031]A device for producing glycine by the alcohol phase method, 4 inlets of the chloroacetic acid dissolving kettle are connected to the methanol pipeline, the bottom valve of the chloroacetic acid dissolving kettle 4 is connected to the mixed crystal synthesis kettle 1; the inlet of the mixed crystal synthesis kettle 1 is connected with the ammonia gas pipeline, the vacuum pipeline and the mother liquor Pipeline, mixed crystal synthesis kettle 1 clamping socket connected to circulating water pipeline, mixed crystal synthesis kettle bottom valve connected to centrifuge; centrifuge 5 inlet connected to mixed crystal pipeline, methanol pipeline, nitrogen pipeline, extraction liquid pipeline, mother liquor discharge port of centrifuge The mother liquor receiving tank 6 and the dilute methanol tank 8; the bottom valve pipeline of the mother liquor receiving tank 6 is connected with the mother liquor jacket tank 3 through the mother liquor pump; the dilute methanol tank 8 is connec...

Embodiment 2

[0033] In a K2000L chloroacetic acid dissolution kettle, dissolve 1000kg solid chloroacetic acid (95.7%) with 1000L methanol and stir well. Dissolve 400kg of urotropine in a K8000L mixed crystal synthesis kettle with 2000L of methanol, stir well, and raise the temperature to 45°C. Pass ammonia gas into the mixed crystal synthesis kettle at 200kg / h, and drop the methanol solution of chloroacetic acid into the mixed crystal synthesis kettle at 600L / h at the same time, measure the pH once every 15min, maintain pH=7.5 in the whole reaction process, pass the mixing The coil and jacket in the crystal synthesis kettle control the temperature in the kettle to 50°C, and the total amount of ammonia passing through is about 340kg. When the methanol solution of chloroacetic acid is added dropwise, the heat preservation timer starts, and the heat preservation time is 4h. The synthetic liquid in the mixed crystal synthesis kettle is centrifuged out of the mixed crystal by centrifugation, a...

Embodiment 3

[0037] In a K2000L chloroacetic acid dissolution kettle, dissolve 1000kg of solid chloroacetic acid (95.1%) with 1000L methanol and stir thoroughly. Dissolve 300kg of urotropine in a K8000L mixed crystal synthesis kettle with 2000L of methanol, stir well, and raise the temperature to 45°C. Pass ammonia gas into the mixed crystal synthesis kettle at 200kg / h, and drop the methanol solution of chloroacetic acid into the mixed crystal synthesis kettle at 600L / h at the same time, measure the pH once every 15min, maintain pH=7.5 in the whole reaction process, pass the mixing The coil and jacket in the crystal synthesis kettle control the temperature in the kettle to 60°C, and the total amount of ammonia passing through is about 340kg. When the methanol solution of chloroacetic acid is added dropwise, the heat preservation timer starts, and the heat preservation time is 3h. The synthetic liquid in the mixed crystal synthesis kettle is centrifuged out of the mixed crystal by centrifu...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a process and a device for producing glycine by an alcohol phase method. The main process comprises the following steps: taking methanol as a solvent, urotropin as a catalystand liquid or solid chloroacetic acid as an initial raw material, firstly introducing ammonia to produce a mixed crystal of glycine and ammonium chloride, centrifuging to obtain a mixed crystal, repeatedly applying the filtrate to synthesis of the mixed crystal, dissolving the mixed crystal by using pure water, extracting a glycine product by using methanol; enabling filtrate after glycine is centrifuged out to enter a rectifying tower to recover methanol, enabling rectified residual liquid to enter a film evaporator, concentrating the rectified residual liquid until water is completely evaporated to directly obtain an ammonium chloride byproduct, and repeatedly using water evaporated from the film evaporator to dissolve mixed crystals. The process mainly uses a glycine synthesis kettle, aglycine extraction kettle, a mixed crystal filtrate elevated tank, a centrifugal machine, a mixed crystal filtrate receiving tank, a chloroacetic acid dissolving kettle, a methanol rectifying tower,a film evaporator, and the like. According to the method, the unit consumption levels of urotropin, liquid ammonia, and steam can be greatly reduced, the production cost is further reduced, and no wastewater is generated.

Description

technical field [0001] The invention discloses a device and process for producing glycine by an alcohol phase method, which belongs to the technical field of chemical production, and in particular relates to a new method for synthesizing glycine by an alcohol phase method and reducing waste water. Background technique [0002] Glycine is aminoacetic acid, as an important fine chemical intermediate and chemical raw material, it is widely used in the fields of pesticide glyphosate, medicine, food and feed additives, etc. At present, the domestic industrialized production process of glycine still adopts the traditional ammonolysis method of chloroacetic acid using water as a solvent. This method has the following problems: (1) High production cost. The catalyst urotropine cannot be recovered; 1 ton of glycine needs to consume about 6-7 tons of steam; the recovery of low-value-added ammonium chloride requires high equipment and pipelines, high maintenance frequency, and high equ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C07C227/08C07C227/40C07C229/08
CPCC07C227/08C07C227/40C07C229/08
Inventor 姚红刘三六王伟
Owner HUBEI TAISHENG CHEM
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap