Oral helicobacter pylori (HP) inhibiting cream and production process thereof

An oral and lysozyme technology, applied in the directions of antibacterial drugs, ointment delivery, plant/algae/fungus/moss components, etc., can solve the problems of weak sterilization ability, repeated oral Helicobacter pylori disease, etc., to improve the bactericidal effect, The effect of preventing sore gums and reducing side effects

Pending Publication Date: 2020-06-09
森淼科技(嘉兴)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, the existing oral antibacterial agents have weak sterilizing ability, resulting in repeated oral Helicobacter pylori disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] An oral HP antibacterial ointment, including 3 parts of aloe extract, 5 parts of propolis extract, 2 parts of xylitol, 3 parts of eugenol, 1 part of mint extract, 3 parts of papain, 3 parts of lysozyme, mastic gum 10 parts, ε-polylysine 2 parts, Chinese medicine extract 10 parts, thickener 10 parts, moisturizing agent 10 parts, foaming agent 5 parts, friction agent 30 parts, purified water 15 parts.

[0023] On the basis of the foregoing examples, the Chinese medicine extract consists of chrysanthemum extract 8%, licorice extract 45%, paeonol 12%, Dendrobium officinale 12%, Bletilla striata extract 18%, Radix Notoginseng powder. 15% composition. Among them, the chrysanthemum extract plays a certain role in reducing pain; the licorice extract plays a role in reconciling the effects of various traditional Chinese medicines; paeonol plays a bactericidal effect; Physical activity, and then make it secrete saliva to kill bacteria; Panax notoginseng powder plays a hemostatic...

Embodiment 2

[0031] An oral HP antibacterial ointment, including 5 parts of aloe extract, 6 parts of propolis extract, 3 parts of xylitol, 10 parts of eugenol, 2 parts of mint extract, 4 parts of papain, 4 parts of lysozyme, and mastic gum 12 parts, 5 parts of ε-polylysine, 21 parts of Chinese medicine extract, 12 parts of thickener, 20 parts of humectant, 7 parts of foaming agent, 40 parts of friction agent, 22 parts of purified water.

[0032] On the basis of the foregoing examples, the Chinese medicine extract consists of chrysanthemum extract 8%, licorice extract 45%, paeonol 12%, Dendrobium officinale 12%, Bletilla striata extract 18%, Radix Notoginseng powder. 15% composition. Among them, the chrysanthemum extract plays a certain role in reducing pain; the licorice extract plays a role in reconciling the effects of various traditional Chinese medicines; paeonol plays a bactericidal effect; Physical activity, and then make it secrete saliva to kill bacteria; Panax notoginseng powder ...

Embodiment 3

[0040]An oral HP antibacterial ointment, including 8 parts of aloe extract, 7 parts of propolis extract, 5 parts of xylitol, 15 parts of eugenol, 3 parts of mint extract, 6 parts of papain, 5 parts of lysozyme, and mastic gum 12 parts, 7 parts of ε-polylysine, 30 parts of Chinese medicine extract, 12 parts of thickener, 25 parts of humectant, 7 parts of foaming agent, 45 parts of friction agent, 28 parts of purified water.

[0041] Further, the Chinese medicine extract is composed of 8% chrysanthemum extract, 45% licorice extract, 12% paeonol, 12% Dendrobium officinale, 18% Bletilla striata extract, and 15% Sanqi powder.

[0042] Further, the production process of the oral HP antibacterial ointment is:

[0043] S1: Mixing, the weighed aloe extract, propolis extract, xylitol, eugenol, peppermint extract, papain, lysozyme, mastic gum, ε~polylysine, traditional Chinese medicine extract, moisturizing Add the agent and friction agent into the pre-dissolved pot, then add pure water...

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Abstract

The invention discloses oral helicobacter pylori (HP) inhibiting cream and a production process thereof. The oral HP inhibiting cream comprises 3-8 parts of an aloe extract, 5-7 parts of a propolis extract, 2-5 parts of xylitol, 3-15 parts of eugenol, 1-3 parts of a peppermint extract, 3-6 parts of papain, 3-5 parts of lysozyme, 10-12 parts of mastic gum, 2-7 parts of epsilon-polylysine, 10-30 parts of a traditional Chinese medicine extract, 10-12 parts of a thickener, 10-25 parts of a moisturizer, 5-7 parts of a foaming agent, 30-45 parts of an abrasive agent and 15-28 parts of purified water. The prepared oral HP inhibiting cream can inhibit and kill HP in an oral cavity, has a better bacterium inhibiting effect on multiple aerobic bacteria and anaerobic bacteria, and can prevent breeding of harmful strains in the oral cavity and regulate the microecological balance of the oral cavity. Meanwhile, the oral HP inhibiting cream also combine traditional Chinese medicine components, the mastic gum and the epsilon-polylysine capable of removing halitosis and dental plaque, clearing inflammation and removing internal heat and preventing gum swelling and aching and bleeding, so that theoral HP inhibiting cream has small side effects and remarkable sterilization effects.

Description

technical field [0001] The invention relates to the technical field of antibacterial ointment, in particular to oral HP antibacterial ointment and its production process. Background technique [0002] Oral Helicobacter pylori is helical, microanaerobic, including Helicobacter pylori canis, Helicobacter gastricus, Helicobacter nigeri, Helicobacter lapni and Helicobacter salomonei, and is currently known to be able to survive in the stomach of animals. Survival of bacteria that require very harsh growth conditions. In 1983, it was successfully isolated from the gastric mucosal biopsy tissue of patients with chronic active gastritis for the first time. It is a microbial species known to be able to survive in the stomach and oral cavity. Oral Helicobacter pylori can cause bad breath, oral ulcers, chronic pharyngitis, periodontitis, etc. [0003] Oral Helicobacter pylori has strong infectivity, wide spread, strong drug resistance, and has a unique "biofilm" structure, which mak...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61K9/06A61K47/26A61K47/42A61K47/34A61P1/02A61P31/04A61K31/12A61K35/644
CPCA61K9/006A61K9/06A61K31/12A61K35/644A61K36/258A61K36/287A61K36/484A61K36/534A61K36/886A61K36/896A61K36/898A61K36/8984A61K47/26A61K47/34A61K47/42A61P1/02A61P31/04A61K2300/00
Inventor 杨科
Owner 森淼科技(嘉兴)有限公司
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