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Prediction model for organ failure induced by acute pancreatitis

A technology of acute pancreatitis and prediction model, applied in the field of neural network, it can solve the problems of irregular and non-equidistant sampling, reducing the utility of data, unable to comprehensively consider the data, etc., to achieve the effect of high precision and increase decision-making ability.

Inactive Publication Date: 2020-06-05
WEST CHINA HOSPITAL SICHUAN UNIV
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Problems solved by technology

[0002] The current mathematical models for the prediction of organ failure in acute pancreatitis in my country mainly focus on traditional statistical methods, some of which do not consider the information of the time dimension, and some of which consider the time information but cannot handle heterogeneous events and irregular and non-equidistant sampling sequence data; some algorithms forcibly fill in the data artificially and subjectively, which leads to unreliable prediction ability about the end point of the event
The prediction task in the medical field is relatively complex, because there are many factors to be considered. Due to the limitation of its own mechanism, the traditional method cannot comprehensively consider all the data of the patient from the time of admission, which reduces the utility of the data and is difficult to achieve satisfactory results. The prediction accuracy of

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  • Prediction model for organ failure induced by acute pancreatitis
  • Prediction model for organ failure induced by acute pancreatitis
  • Prediction model for organ failure induced by acute pancreatitis

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Embodiment Construction

[0058] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings.

[0059] Such as figure 1 , figure 2 As shown, the present invention integrates the medication information, laboratory examination information, electronic medical record information, and radiation system examination information of patients after admission, and organizes them into structured data, retaining the time node information of each event, namely {Variables ,Time};

[0060] Sorting is done in chronological order, and missing values ​​are filled using the Decay mechanism. At the input layer of the network, the Embedding mechanism is used for one-hot encoding of categorical variables, and then mapped to a real vector space of appropriate dimensions, and the numerical event values ​​are normalized and directly introduced.

[0061]The input layer is connected...

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Abstract

The invention discloses a prediction model for organ failure induced by acute pancreatitis, and the model comprises the following steps: S100, preprocessing patient information, and recording events and time nodes by means of {Variables, Time}; s200, sorting the events according to a time sequence, and filling missing values by adopting a Decay mechanism; and S300, carrying out one-hot coding on the data by using an Embedded mechanism, mapping the data to a real vector space, normalizing the data and then inputting the normalized data into a Phased LSTM model. Time gate output is calculated according to the interval time of a patient from admission to the time node of the event, the model training process is accelerated by utilizing the output result of the time gate, the neuron of the output layer is 2, and a softmax function is adopted as an activation function. According to the method, heterogeneous multi-dimensional data can be processed, time information can be flexibly used, andmeanwhile, the judgment of the model is closer to a description of a disease natural process in the real world.

Description

technical field [0001] The invention relates to the field of neural networks, in particular to a prediction model of organ failure induced by acute pancreatitis. Background technique [0002] The current mathematical models for the prediction of organ failure in acute pancreatitis in my country mainly focus on traditional statistical methods, some of which do not consider the information of the time dimension, and some of which consider the time information but cannot handle heterogeneous events and irregular and non-equidistant sampling sequence data; some algorithms forcibly fill in the data artificially and subjectively, which makes the ability to predict the end point of the event unreliable. The prediction task in the medical field is relatively complex, because there are many factors to be considered. Due to the limitation of its own mechanism, the traditional method cannot comprehensively consider all the data of the patient from the time of admission, which reduces th...

Claims

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Application Information

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IPC IPC(8): G16H50/70G16H50/50G06N3/04G06N3/08
CPCG16H50/70G16H50/50G06N3/049G06N3/084G06N3/045
Inventor 兰蓝罗佳伟周小波
Owner WEST CHINA HOSPITAL SICHUAN UNIV
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