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Method for preparing tablet medicine with effects of clearing heat and eliminating stagnation

A technology for clearing away heat and dissipating stagnation and medicine, which is applied in the field of medicine preparation of Qingre Sanjie tablets, which can solve problems such as cracking of the sugar coating layer, achieve stable quality, solve cracking of the sugar coating layer, and solve quality problems

Inactive Publication Date: 2020-06-05
贵州汉方药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The invention solves the quality problem of the existing Qingre Sanjie Tablets that the sugar coating layer is broken during storage, and improves the product quality

Method used

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  • Method for preparing tablet medicine with effects of clearing heat and eliminating stagnation
  • Method for preparing tablet medicine with effects of clearing heat and eliminating stagnation
  • Method for preparing tablet medicine with effects of clearing heat and eliminating stagnation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Embodiment 1: A kind of Qingre Sanjie tablet medicine, is made with the raw material of following weight composition ratio: Plain tablet 125g, hypromellose 0.75g, gelatin 1g, sucrose 37.5g, talcum powder 60g, chrysanthemum white wax 0.1875g , Simethicone 0.0125g and pigment 0.06875g. .

[0046] Specifically include the following steps:

[0047] (1) Weigh hypromellose for later use, and weigh 13 times the mass of hypromellose and boil purified water, put it in a stainless steel mixing bucket, start stirring, slowly sprinkle hypromellose, and wait to mix and stir evenly , there is no particle in the solution, and product A is obtained;

[0048] (2) Put the plain tablets in the coating machine, set the air inlet temperature to 60-70°C, turn on the air inlet and exhaust, and when the air inlet temperature reaches above 55°C, set the speed of the coating machine to 2.5-2.7Hz, turn on The main engine, spraying, atomizing and slurry pumps, spray the prepared product A, and ...

Embodiment 2

[0060] Embodiment 2: A kind of Qingre Sanjie Tablet medicine is made with the raw material of following weight composition ratio: plain tablet 250g, hypromellose 1.75g, gelatin 2.3g, sucrose 80g, talcum powder 130g, chrysanthemum white wax 0.3g , Simethicone 0.02g and pigment 0.1g.

[0061] Concrete preparation steps are identical with embodiment 1.

Embodiment 3

[0062] Embodiment 3: A kind of Qingre Sanjie Tablet medicine is made with the raw material of following weight composition ratio: plain tablet 340g, hypromellose 2.25g, gelatin 2.6g, sucrose 110g, talcum powder 90g, chrysanthemum white wax 0.4g , Simethicone 0.03g and pigment 0.15g.

[0063] Concrete preparation steps are identical with embodiment 1.

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PUM

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Abstract

The invention discloses a method for preparing a tablet medicine with effects of clearing heat and eliminating stagnation. The tablet medicine is prepared from the following raw materials in parts byweight: 125-375 parts of plain tablets, 0.75-2.25 parts of hydroxypropyl methylcellulose, 1-3 parts of gelatin, 37.5-112.5 parts of cane sugar, 60-180 parts of talc powder, 0.1875-0.5625 part of Chinese wax, 0.0125-0.0375 part of dimeticone and 0.06875-0.20625 part of pigment. The method has the beneficial effects of solving the quality problem that the sugar coating of an existing heat-clearing and stagnation-eliminating tablet is broken in the storing process and improving the product quality.

Description

technical field [0001] The invention relates to a preparation method of medicine, in particular to a preparation method of Qingre Sanjie tablet medicine. Background technique [0002] Qingre Sanjie Tablet is a unilateral preparation, and its implementation standard is the Ministry of Health’s Drug Standards for Traditional Chinese Medicine Prescriptions Volume 10 (WS 3- B-3995-98) The main ingredient is Senecio, which has the effects of anti-inflammatory, detoxification, dispelling stagnation and relieving pain. Mainly used for acute conjunctivitis, acute pharyngitis, acute tonsillitis, acute enteritis, bacillary dysentery, upper respiratory tract inflammation, acute bronchitis, lymphadenitis, sore boil pain, dermatitis and eczema. [0003] The Qingre Sanjie tablets produced by our company's original technology were found to have soaking spots and splits during storage, which greatly affected the quality of the tablets. Observation of the retained samples revealed that the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61K9/36A61K9/30A61K9/40A61K9/28A61K47/38A61K47/42A61K47/02A61P27/02A61P11/04A61P1/00A61P29/00A61P1/12A61P31/04A61P11/00A61P17/00A61P17/02
CPCA61K9/2813A61K9/2866A61K9/2873A61K9/2886A61K9/2893A61K36/28A61P1/00A61P1/12A61P11/00A61P11/04A61P17/00A61P17/02A61P27/02A61P29/00A61P31/04
Inventor 杨飞尚秘杨勇莫再霞张仕林吴劲勇葛秋萍
Owner 贵州汉方药业有限公司
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