Method of improving bile duct cancer by TIL immune cells
A technology for immune cells and cholangiocarcinoma, applied in the field of immune cell therapy, can solve the problems of poor chemotherapy sensitivity and prolong survival period, and achieve the effects of less side effects, improved quality of life and strong curative effect.
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[0011] The present invention will be described in detail below in conjunction with specific embodiments.
[0012] The present invention discloses a method for improving cholangiocarcinoma through TIL immune cells. The specific operation steps of the method are: (1) first remove the tumor from the patient; (2) then the tumor tissue is transported to under sterile, cold chain conditions The laboratory uses mechanical treatment and enzymatic digestion methods to separate tumor infiltrating lymphocytes from the tumor, and isolate the initial tumor infiltrating lymphocytes; (3) Add high-dose IL-2 in vitro culture and transformation to infiltrate the initial tumor The lymphocytes were expanded ten thousand times and further purified, and then frozen; (4) Finally, the tumor-infiltrating lymphocytes were returned to the body of the cholangiocarcinoma patient, and the average amount of tumor-infiltrating lymphocytes per injection was 1×10 11 One.
[0013] Improvement case: A 42-year-old pat...
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