Fundus imaging device and imaging method

An imaging device and imaging technology, applied in ophthalmoscopes, eye testing equipment, medical science, etc., can solve the problems of difficult prior information of the optical system, lack of universal applicability, and difficult operation, so as to achieve super-resolution The effect of detection imaging, shortening detection time, and improving resolution

Active Publication Date: 2020-04-28
XIDIAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, the fundus imaging system based on wavefront coding technology requires multiple and large data measurements during the focusing or imaging process, so the whole process takes a long time and requires the patient's high cooperation for a long time, and the actual operation is extremely vulnerable. Interference, difficult to operate
In addition, in the process of image sampling, the wavefront coding technology needs to obtain the prior information of the optical system for modulation. However, in the actual application process, due to the wide variety and different nature of eye diseases, it is difficult to obtain the prior information of the optical system. Difficult and not universally applicable

Method used

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  • Fundus imaging device and imaging method
  • Fundus imaging device and imaging method

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Experimental program
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Embodiment 1

[0045] See figure 1 , figure 1 It is a schematic structural diagram of a fundus imaging device provided by an embodiment of the present invention. The imaging device is mainly used for fundus imaging, including fundus imaging with turbidity in the eyeball and fundus imaging without turbidity in the eyeball, and can also be applied to imaging of thin biological tissues, including thin biological tissues with hidden objects such as physiological lesions. Tissues and thin biological tissues without hidden objects such as physiological lesions. This embodiment is mainly described by taking fundus imaging in which there is opacity in the eyeball (the lens or vitreous body inside the eyeball is opaque) as an example.

[0046] figure 1 The fundus imaging device includes: LED light source 1 , light modulation unit 2 , detection unit 3 , light filtering unit 5 , relay lens 6 and optical signal receiver 4 . Among them, A is the target eyeball with turbidity.

[0047] The LED light ...

Embodiment 2

[0060] On the basis of Example 1, please refer to figure 2 , figure 2 It is a schematic flowchart of a fundus imaging method provided by an embodiment of the present invention. The fundus imaging method utilizes the fundus imaging device of Embodiment 1 to image the turbid fundus, specifically including steps:

[0061] S1. The point spread function graph of the acquisition system.

[0062] Specifically, firstly, the target eyeball A is replaced by a reflective pinhole, which is placed on the back focal plane of the detection unit 3 . Then, turn on the LED light source 1 to make it emit spatially incoherent light. Next, make the spatially incoherent light pass through the light modulation unit 2, modulate the spatially incoherent light into parallel light rays, and change the optical path direction of the parallel light rays. After that, the detection unit 3 is used to converge the parallel light rays after changing the direction of the optical path to obtain the incident...

Embodiment 3

[0081] See image 3 , image 3 It is a schematic structural diagram of another fundus imaging device provided by an embodiment of the present invention. The fundus imaging device mainly images the fundus without turbidity in the eyeball, and can realize super-resolution imaging of the fundus; the fundus imaging device can also be applied to super-resolution imaging of thin biological tissues with physiological lesions. In this embodiment, the fundus super-resolution imaging is taken as an example for specific description.

[0082] image 3 The fundus imaging device includes: LED light source 1 , light modulation unit 2 , detection unit 3 , light filter unit 5 , relay lens 6 , scattering medium 7 and optical signal receiver 4 . image 3 Among them, B is the eyeball without turbidity.

[0083] For the description of the LED light source 1 , the light modulation unit 2 , the detection unit 3 , the light filter unit 5 , the relay lens 6 and the optical signal receiver 4 , plea...

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Abstract

The invention relates to a fundus imaging device and an imaging method. The fundus imaging device comprises an LED (light emitting diode) light source, a light modulating unit, a detection unit and alight signal receiver which are sequentially arranged along a light path direction, wherein the LED light source is used for emitting spatial incoherent light; the light modulating unit is used for modulating the spatial incoherent light into parallel light and used for changing the light path direction of the parallel light; the detection unit is used for converging the parallel light of which the light path direction is changed so as to obtain incident light for incidence in an eyeball; the incident light is reflected by the fundus of the eyeball to generate emitting light in a direction opposite to that of the incident light; and the light signal receiver is used for recording a speckle pattern formed by the emitting light. According to the fundus imaging device, different optical elements are integrally designed, imaging of an object to be tested can be achieved by acquiring single-frame speckle patterns in the focusing and imaging process, and the whole process takes short time, is small in operation difficulty, has universal applicability and is applicable to light scattering such as vitreous opacitees and no-light scattering situations.

Description

technical field [0001] The invention belongs to the technical field of optical computing imaging, and in particular relates to a fundus imaging device and an imaging method. Background technique [0002] Fundus imaging is an important technical application of optical detection methods in the field of biomedicine. It is currently the most important means of eye detection and disease auxiliary diagnosis and monitoring, and it is also the main technical approach for frontier research on the retina. By taking and diagnosing fundus images, not only eye diseases can be found, but other systemic diseases (such as diabetes, etc.) can also be detected. [0003] Since the Renaissance in the 16th century, Western society has begun preliminary research on the human eye; in the 17th and 18th centuries, Western researchers successively recognized the refractive imaging of the eye and mastered the technology of cataract extraction; with the development of research and understanding In the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B3/12A61B3/14G02B27/09
CPCA61B3/0008A61B3/12A61B3/14G02B27/0955
Inventor 刘杰涛邵晓鹏孙杨帆计婷高苗董磊
Owner XIDIAN UNIV
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