Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Probiotic preparation and preparation method thereof

A probiotic preparation and probiotic technology, applied in the field of probiotic preparation and its preparation, can solve the problems of short probiotic activity retention time and single effect of probiotic preparation, achieve high-quality and high-efficiency processing and preparation, and the overall quality is stable and reliable High degree, the effect of regulating the balance of intestinal flora

Pending Publication Date: 2020-04-21
成都三勒浆药业集团四川华美制药有限公司
View PDF4 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the technical problems of single effect of probiotic preparations and short retention time of probiotic activity in the prior art, the present invention provides a probiotic preparation and a preparation method thereof

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Probiotic preparation and preparation method thereof
  • Probiotic preparation and preparation method thereof
  • Probiotic preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-10

[0051] Preparation of probiotic preparations

[0052] According to the raw materials and raw material ratios of the probiotic preparations in Table 1, the probiotic preparation products of Examples 1-10 were prepared.

[0053] Table 1 is the raw material and raw material proportioning situation of embodiment 1-10 probiotic preparation

[0054]

[0055] The preparation steps are as follows:

[0056] Step a, mixing inulin and xylo-oligosaccharide in proportion and stirring to obtain the first mixed material.

[0057] Step b, mixing the first mixed material obtained in step a with Bifidobacterium lactis HN019 and Bifidobacterium lactis V9 in an equal increasing manner, and then mixing in a three-dimensional mixer for 40 minutes at a speed of 30 r / min to obtain a second mixture material.

[0058] Step c. Subpackage the second mixed material prepared in step b with a powder packaging machine to obtain a powder probiotic preparation in bags. Wherein, the ambient temperature o...

Embodiment 11

[0065] Preparation of probiotic preparations

[0066] Take the following raw materials according to the weight ratio: 62.46 parts of dietary fiber (35.67 parts of inulin; 22.38 parts of xylo-oligosaccharides; 2.97 parts of polydextrose; 1.44 parts of red bracken fiber powder); 7.9 parts of probiotics (Bifidobacterium lactis V9 is 3.3 parts; Bifidobacterium lactis HN019 is 4.6 parts;); cheese 0.27 parts; sugar alcohol 6.48 parts; cranberry powder 1.65 parts.

[0067] Mix the dietary fiber, sugar alcohol, cheese, and cranberry powder thoroughly, and then mix the probiotics and other materials in equal increments. Then mix the mixed material in a three-dimensional mixer at a speed of 20r / min for 35min, and then pack the resulting mixed material with a powder packaging machine, and pack it into a product of 3g per bag. 10 CFU / bag. It is required that the production and processing temperature be controlled at about 22±2°C, and the humidity be controlled at about 30+5%.

[0068] ...

Embodiment 12

[0090] From the data in Table 2, it can be seen that when the weight ratio of the dietary fiber to the probiotic is 3 to 8:1, the dietary fiber in the preparation provides a protective landing site for the probiotic, so that the activity of the probiotic can be maintained during production, Optimum activity can be maintained during transportation and during the shelf life of the product. In order to further test the experiment of the improvement of the constipation and diarrhea of ​​the mice by the probiotic preparation products of Examples 3-8, the mouse test of Example 12 was carried out, and the experimental process was the same as that of the mouse constipation and diarrhea experiment in Example 11 The process is consistent, and Table 7 shows the ink propulsion rate and diarrhea improvement rate and the ratio of raw materials in the probiotic preparation product during the mouse experiment of Examples 3-8.

[0091] Table 7 Example 3-8 probiotic preparation raw material rat...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Activeaaaaaaaaaa
Login to View More

Abstract

The invention relates to a probiotic preparation and a preparation method thereof. The probiotic preparation is prepared from the following raw materials by weight: 28-75 parts of dietary fibers and 2-30 parts of probiotics, wherein the weight ratio of the dietary fibers to the probiotics is (1-10): 1. The activity of the probiotics is 0.3*10<10> CFU / g to 4*10<10> CFU / g. The invention further provides an equivalent incremental mixing method for preparing the probiotic preparation. Dietary fibers in the preparation provide protective sites for probiotics, so that the activity of the probioticscan be kept for a long time, the optimal active state can be kept under the conditions of production, transportation and the like, and the corresponding probiotic preparation can effectively regulateintestinal flora balance and maintain intestinal health, and has the effects of preventing and treating constipation and diarrhea.

Description

technical field [0001] The invention relates to the technical field of nutrition and health food, in particular to a probiotic preparation and a preparation method thereof. Background technique [0002] In recent years, many studies have shown that the intestinal flora is closely related to the health status of the host, which closely affects the host's nutrient absorption, substance metabolism, immunity, and gastrointestinal tract development. Factors such as the host's own genotype, age, and immune system It plays an important role in the formation and stability of the intestinal flora structure. The gastrointestinal system is particularly important to the health of the human body. The intestinal tract is the largest digestive organ, the largest immune organ, and the largest micro-ecological environment in the human body. As the boundary between the inside and outside of the human body, intestinal health affects the disease and health status of the entire body . The huma...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A23L33/135A23L33/21
CPCA23L33/135A23L33/21A23V2002/00A23V2200/32
Inventor 刘海燕罗明锋杜志琳郑有德宋昱莫芳胡利黄辉李采艳莫太刚李再兴樊三虎
Owner 成都三勒浆药业集团四川华美制药有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com