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Microwave ablation tissue Young modulus real-time evaluation method and device based on reduced scattering coefficient

A technology of reduced scattering coefficient and microwave ablation, applied in microwave surgical instruments, parts of surgical instruments, medical science, etc., can solve problems such as the effective relationship model of reduced scattering coefficient and Young's modulus without microwave ablation, etc. Achieving the effect of low price and easy operation

Active Publication Date: 2020-04-14
NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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Problems solved by technology

[0005] There is currently no effective relationship model for the reduced scattering coefficient and Young's modulus during microwave ablation

Method used

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  • Microwave ablation tissue Young modulus real-time evaluation method and device based on reduced scattering coefficient
  • Microwave ablation tissue Young modulus real-time evaluation method and device based on reduced scattering coefficient
  • Microwave ablation tissue Young modulus real-time evaluation method and device based on reduced scattering coefficient

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Embodiment Construction

[0034] Below in conjunction with embodiment the present invention will be further described.

[0035] Such as figure 1 Shown is a flowchart of a method for real-time evaluation of Young's modulus of microwave-ablated tissue based on reduced scattering coefficient provided by an embodiment of the present invention, including the following steps:

[0036] S1. Build a simultaneous real-time acquisition system for microwave ablation to reduce scattering coefficient and Young's modulus;

[0037] S2. Obtaining μ' under different ablation doses s Change data synchronously with E;

[0038] S3. Establish multiple groups of E-μ' by polynomial data fitting s Relational equations, with the coefficient of determination (goodness of fit) of each group of equations as the weight;

[0039] S4. Using the obtained multiple sets of relational equations and determination coefficients to obtain the final E-μ' s relational model;

[0040]S5. Check the established model and determine the error...

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Abstract

The invention discloses a microwave ablation tissue Young modulus real-time evaluation method based on a reduced scattering coefficient. The hardness (Young modulus, E) of a tissue is estimated in real time according to the obtained reduced scattering coefficient (mu's) of the tissue in the microwave ablation process. The method comprises the following steps: first, establishing an in-vitro pork liver microwave ablation reduced scattering coefficient and Young modulus real-time synchronous acquisition system to obtain a large amount of mu's and E synchronous change data in the microwave ablation process; and then, establishing a plurality of groups of E-mu's relation equations through data fitting, and obtaining a final E-mu's relation model by taking a determination coefficient (goodnessof fit) of each group of equations as a weight. According to the method, the correlation between mu's and E is established, and the hardness parameter of the tissue can be calculated by measuring thereduced scattering coefficient of the tissue. The method has great significance in evaluating the real-time curative effect of tumor microwave ablation, and has important value in establishing a multi-mode tumor microwave ablation curative effect evaluation system.

Description

technical field [0001] The invention relates to the field of evaluation of microwave ablation curative effect, in particular to a method and device for real-time evaluation of Young's modulus of microwave ablation tissue based on reduced scattering coefficient. Background technique [0002] Microwave thermal ablation therapy is considered to be another new type of effective treatment for malignant tumors after surgery, chemotherapy, radiotherapy, immunotherapy, etc. It has played a huge role in tumor treatment and has been widely used in common tumors such as liver cancer, lung cancer, kidney cancer, thyroid cancer, intestinal cancer, and uterine fibroids. However, there are still many scientific and technical problems to be solved in microwave tumor thermal ablation, one of the most important ones is the real-time curative effect evaluation problem in microwave ablation therapy. At present, the reduced scattering coefficient is mainly used as a determination factor for tum...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B18/18
CPCA61B18/1815A61B2018/00773
Inventor 钱志余晋晓飞李怡燃刘文文沐勇杰冯宇俞钦栋朱柔君邹止寒
Owner NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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