Hemostatic material for war wounds as well as preparation method and application thereof

Abstract

The invention discloses a hemostatic material for war wounds as well as a preparation method and an application thereof, which relate to the technical field of biomedical materials, and the hemostaticmaterial is characterized by comprising an electrostatic spinning outer membrane and hydrogel applied to the surface of the electrostatic spinning outer membrane, and the components of the electrostatic spinning outer membrane and the hydrogel are respectively one of PEG-NHS (polyethylene glycol-succinimide ester) or PEG-NH2 (polyethylene glycol amino). The preparation method comprises the following steps: 1) preparing preparation materials; 2) preparing the electrostatic spinning outer membrane; and 3) preparing the hydrogel. The hemostatic material is a hemostatic product applied to trauma,wound, thoracic cavity and abdominal cavity operations or internal organs and vascular bleeding. The hemostatic material has the properties of rapid coagulation hemostasis, moisture retention, bacteriostasis, tissue repair promotion, high mechanical strength, strong wound adhesion and the like, so that an efficient and convenient self-rescue and mutual-rescue material can be provided for war wound wounded persons, the death rate is conveniently reduced, and the war wound treatment level is improved.

Description

technical field [0001] The invention relates to the technical field of biomedical materials, more specifically, it relates to a hemostatic material for war wounds and its preparation method and application. Background technique [0002] Traumatic bleeding is one of the most common injuries at the scene of various accidents, and uncontrolled bleeding is the leading cause of death at the scene of the wounded. Even if the wounded can be sent to the hospital for emergency treatment, massive blood loss before the hospital will still cause higher mortality and serious complications in the later period. In fact, most casualties from bleeding were preventable. Traditional hemostatic materials such as cotton gauze and bandages are not ideal for hemostatic effects on common wounds such as irregular shapes, deep, narrow and ruptured arteries. It is of great significance to effectively control the hemorrhage of the wounded at the scene and before the hospital. Therefore, a fast, safe ...

AI Technical Summary

Problems solved by technology

However, it also has the following problems: 1. The long-term preservation of the hydrogel; 2. The hemostatic effect of the two-component hydrogel is good, but the operation is relatively complicated, and the hemostatic operation cannot be performed during the mixing process; 3. While the hydrogel adheres to the bleeding site and achieves hemostasis, the lack of a barrier layer can lead to adhesion of surrounding tissue and possible contaminants can enter the hydrogel and cannot be removed

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