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Wrinkle-removing firming stock solution containing recombinant collagen

A technology for recombining collagen and firming, which can be applied to medical preparations containing active ingredients, preparations for skin care, cosmetics, etc. Moisturizing and water-locking ability, excellent moisturizing and water-locking, easy-to-absorb effect

Inactive Publication Date: 2020-03-31
JIANGSU JLAND BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the origin of animals, there are still biological safety hazards, which limit the wide application of collagen in various products such as cosmetics, food, and medicine, and its wrinkle-removing and firming effect is still not ideal.

Method used

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  • Wrinkle-removing firming stock solution containing recombinant collagen
  • Wrinkle-removing firming stock solution containing recombinant collagen
  • Wrinkle-removing firming stock solution containing recombinant collagen

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] An anti-wrinkle and firming stock solution containing recombinant collagen, comprising the following components by mass percentage: 0.4% recombinant collagen, 30% butanediol, 2.5% 1,2-hexanediol, polyethylene glycol-8 10 %, sodium hyaluronate 0.4%, polyglutamic acid 0.4%, acetyl hexapeptide-8 0.07%, and the balance is water. Prepared by the following steps: according to the formula ratio, add sodium hyaluronate, polyglutamic acid and recombinant collagen into butanediol, stir until mixed evenly, then add 1,2-hexanediol, polyethylene glycol-8 and acetyl hexapeptide-8, add water to 100%, stir evenly until completely dissolved, and obtain the anti-wrinkle and firming original solution containing recombinant collagen.

[0022] In this example, the recombinant collagen is produced by fermentation of Pichia pastoris with a preservation number of CGMCC No. 5021, and other raw materials are conventional products sold in the market.

[0023] In this embodiment, the various raw ...

Embodiment 2

[0025] 1. Experimental products:

[0026] Cream: Water 68.65%, Carbomer 0.2%, Triethanolamine 0.2%, Xanthan Gum 0.1%, Glycerin 4%, Butylene Glycol 3%, Biosugar Gum-20.5%, Cetearyl Alcohol 1%, C20- 22 Alcohol Phosphate (and) C20-22 Alcohol 0.8%, Glyceryl Stearate 0.5%, Caprylic / Capric Glycerides 3%, Dimethicone 3%, Shea Butter (BUTYROSPERMUM PARKII) 4.5%, methylparaben 0.15%, caprylyl hydroxamic acid 0.4%, 1,2-hexanediol 0.5%.

[0027] The anti-wrinkle and firming original solution containing recombinant collagen contains the following ingredients by mass percentage: recombinant collagen 0.4%, butanediol 30%, 1,2-hexanediol 2.5%, polyethylene glycol-8 10%, Sodium hyaluronate 0.4%, polyglutamic acid 0.4%, acetyl hexapeptide-8 0.07%, and the balance is water.

[0028] Anti-wrinkle and firming liquid without recombinant collagen, including the following ingredients by mass percentage: butanediol 30%, 1,2-hexanediol 2.5%, polyethylene glycol-810%, sodium hyaluronate 0.4% , polyg...

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Abstract

The invention discloses a wrinkle-removing firming stock solution containing recombinant collagen, which belongs to the field of cosmetics. The wrinkle-removing firming stock solution is prepared fromthe following components in percentage by mass: 0.1%-1% of recombinant collagen, 10%-40% of butanediol, 1%-5% of 1,2-hexanediol, 1%-10% of polyethylene glycol-8, 0.1%-0.5% of sodium hyaluronate, 0.1%-0.5% of polyglutamic acid, 0.05%-2% of acetyl hexapeptide-8 and the balance of water. The recombinant collagen from microbial fermentation is compounded with other raw materials, so that the problemsof precipitation, discoloration, precipitation and the like are avoided. The wrinkle-removing firming stock solution disclosed by the invention not only has excellent moisturizing and water-locking effects on skin, but also has the effects of firming and removing wrinkles.

Description

technical field [0001] The invention belongs to the field of cosmetic preparations, and relates to a wrinkle-removing and firming stock solution containing recombinant collagen. Background technique [0002] Women start to lose collagen at the age of 20, and enter the peak period of loss at the age of 25. At the age of 40, the collagen content is less than half of that at the age of 18. The loss of collagen means the appearance of wrinkles and the aging of the appearance. Anti-aging cosmetic preparations are attracting more and more people's attention, and their share of the total market volume continues to grow every year. Supplementing enough collagen can achieve the effect of firming the skin and removing wrinkles. At present, the collagen used in anti-wrinkle products on the market is mostly extracted from animal bone or skin, such as marine collagen extracted from deep-sea fish. However, because it is derived from animals, there are still hidden dangers in biological...

Claims

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Application Information

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IPC IPC(8): A61K8/88A61K8/86A61K8/73A61K8/65A61K8/34A61K8/64A61Q19/00A61Q19/08
CPCA61K8/345A61K8/64A61K8/65A61K8/735A61K8/86A61K8/88A61K2800/85A61Q19/00A61Q19/08
Inventor 沈凤娟冯丽萍刘朱焰朱逸丽徐鹏程季乐赵健烽
Owner JIANGSU JLAND BIOTECH CO LTD
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