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Porous biological artificial eye seat

A bio-ceramic, prosthetic eye seat technology, applied in eye implants and other directions, can solve the problems of high price, long process and complex process

Pending Publication Date: 2020-03-10
胡可辉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, although porous prosthetic sockets made of different materials have such advantages, these porous prosthetic sockets are all made by template method, which involves complicated process, long process and difficult preparation due to the post-treatment of template agent
Also, the bulky templating agent required to allow for the infiltration of new tissue into the porous prosthetic socket is generally expensive
In addition, when using the template method, the doctor cannot design the microporous structure, so the vascularization process after implantation is not controllable, and it is difficult to ensure the quality and stability of the eyeball
Moreover, the overall shape of the prosthetic eye seat made by the mold needs to be cut, carved or polished after the mold is prepared. The mold opening time is long and the cost is high, and it is impossible to realize customized production for different patients.

Method used

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  • Porous biological artificial eye seat
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Use hydroxyapatite: tricalcium phosphate: biological glass 4:2:1, mix 20nm-500nm particle size powder as bioceramic material 50 parts, acrylic resin monomer 40 parts as photosensitive resin binder, 5 parts The PMMA used as a pore-forming agent, 2 parts of polymethylcellulose as a dispersant, and 1 part of MgO as a sintering aid were mixed uniformly with a mixer and then defoamed to obtain a bioceramic slurry for 3D printing.

[0034] Modeling of the prosthetic eye socket is carried out based on the scanned eye socket data of the patient. The model of the prosthetic eye socket is a spherical shape with a diameter of 25 mm. The spherical cap with a height of 10 mm on one side is a dense thin shell with a thickness of 1 mm. And the rest of the surface has uniformly distributed pores of 0.3 mm to 1 mm, which are interconnected. The model as figure 1 shown.

[0035] A 3D printer of the Autocera type manufactured by Beijing Shiwei Technology Co., Ltd., which can be used for...

Embodiment 2

[0038] The ellipsoid whose polar radius is greater than the equatorial radius is used as the artificial eye seat model, and the spherical cap with a height of 6mm from a pole is a dense thin shell with a thickness of 2mm, and the inside and the rest of the surface have a uniform distribution of 0.1mm to 0.8mm pores, which are interconnected.

[0039] The prosthetic eye seat was prepared in the same manner as described in Example 1 except for the difference of these models.

Embodiment 3

[0041] Using the 1:1 mixed powder of bioglass and calcium sulfate as the raw material of bioceramic powder, the prosthetic eye seat was prepared in the same manner as described in Example 1. The final sintering temperature is 1200°C for 1h.

[0042] According to the porous prosthetic eye socket of the present invention, 3D printing is used to form designable interconnected holes, and the holes are larger in size than the holes generated by the pore-forming agent (template agent), which is beneficial to newborns. Blood vessels and tissue seep into the porous socket. The secondary holes and the final holes in the prosthetic eye seat of the present invention are small in size and can be used to deliver required nutrients and the like to blood vessels and tissues formed in the macroscopic holes.

[0043] In addition, the porous prosthetic eye socket of the present invention is shaped based on the patient's eye socket data, and its size is more suitable for each patient.

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Abstract

The invention relates to a porous biological artificial eye seat and a preparation method thereof. The artificial eye seat is prepared from bioceramic and is a spherical body with a diameter of 10-30mm; a spherical crown at one side of the artificial eye seat is a compact thin shell with a thickness of 0.2-3mm; and the inner part of the artificial eye seat and other surfaces of the artificial eyeseat are provided with macroscopic pores with a thickness of 0.1-1mm and more preferably 0.3-1mm which are uniformly distributed, wherein the surfaces and the inner macroscopic pores communicate witheach other. The artificial eye seat also comprises secondary pores and final pores which are uniformly distributed, wherein the size of the secondary pores is 1-100 microns, the size of the final pores is less than 1 micron, and porosity of the artificial eye seat is 60-95%. The porous artificial eye seat is formed by 3D printing, the size of the pores is larger than the size of pores generated byadopting a pore-forming agent, the shape and the size can be freely designed, and the penetration of new blood vessels and tissues into the porous artificial eye seat is facilitated. The secondary and final pores in the eyelid seat provided by the invention are small in size and can be used to deliver desired nutrients and the like to blood vessels and tissues formed in the macropores.

Description

technical field [0001] The invention relates to a ceramic spherical artificial eye seat and a preparation method thereof. More specifically, the present invention relates to a bioceramic spherical prosthetic eye socket with multi-level holes and a preparation method thereof. Background technique [0002] Implanting a prosthetic eye is a commonly used restoration treatment for restoring the appearance after eyeball enucleation. After the implantation of the prosthetic eye, the patient can install a prosthetic eye on the prosthetic eye to restore the appearance to the greatest extent. [0003] Prosthetic eye sockets in the prior art can be divided into several categories according to materials. One is a solid sphere made of a silicone material; one is a porous socket made of coral hydroxyapatite; and a porous socket is made of a polymer. [0004] However, after the above-mentioned silicone prosthetic eye socket is implanted, a fibrous membrane will be formed around it, causi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/14
CPCA61F2/141
Inventor 胡可辉万力成明
Owner 胡可辉
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