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Extraction method of total flavone of eucommia bark and application of total flavone of eucommia bark in antioxidants and hypoglycemic agents

An extraction method and a technology of total flavonoids, which are applied in the direction of anti-toxic agents, medical preparations containing active ingredients, and pharmaceutical formulas, can solve the problems of low extraction rate and no research on the application of extracts, etc.

Active Publication Date: 2020-03-06
JISHOU UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the extraction rate of this method is not high, and the application of the extract has not been studied

Method used

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  • Extraction method of total flavone of eucommia bark and application of total flavone of eucommia bark in antioxidants and hypoglycemic agents
  • Extraction method of total flavone of eucommia bark and application of total flavone of eucommia bark in antioxidants and hypoglycemic agents
  • Extraction method of total flavone of eucommia bark and application of total flavone of eucommia bark in antioxidants and hypoglycemic agents

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0035] 1 Experimental part

[0036] 1.1 Experimental instruments and medicines

[0037] 1.1.1 Experimental Instruments

[0038] BJ-150 multifunctional pulverizer (Deqing Baijie Electric Co., Ltd.); GB / T6003 1-2012 standard inspection sieve (Shaoxing Shangyu Huafeng Hardware Instrument Co., Ltd.); 101-1AB electric blast drying oven (Tianjin Tai Ster Instrument Co., Ltd.); FA2004 electronic balance (Shanghai Sunny Hengping Scientific Instrument Co., Ltd.); microwave synthesis and extraction system (Shanghai Yiyao Instrument Technology Development Co., Ltd.); SHB-III circulating water multi-purpose vacuum pump (Gongyi Zhongtian Instrument Technology Co., Ltd.); microplate reader (SPECTRA max PLUS384); pipette gun (Dragonlab100-1000)

[0039] 1.1.2 Experimental drugs

[0040] Eucommia samara was picked in Zhangjiajie, Hunan Province in March 2018; absolute ethanol (analytical grade, Tianjin Fuyu Fine Chemical Co., Ltd.), rutin sample (20 mg from Shanghai Ronghe Pharmaceutical T...

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Abstract

The invention relates to research of an extract of total flavone of eucommia bark, and in particular to an extraction method of total flavone of eucommia bark and an application of the total flavone of eucommia bark in antioxidants and hypoglycemic agents. According to the invention, eucommia bark is taken as a raw material to extract total flavone in the eucommia bark by a microwave-assisted method, wherein an optimal extraction condition of the total flavone is determined by setting a single-factor experiment and optimizing a response surface. The invention provides the application of the total flavone in oxidation resistance and hypoglycemic activity.

Description

technical field [0001] The invention belongs to the research related to the extract of eucommia ulmoides, in particular to a method for extracting total flavonoids of eucommia ulmoides and its application in antioxidants and hypoglycemic agents. Background technique [0002] The fruit of Eucommia ulmoides is developed from two oblong carpels, and its essence is a nut. Because it is surrounded by thin leathery wings, it is also called samara customarily. Eucommia samara is flat, oblong. There are wings around, the wings are leathery, and the top is slightly concave. The fruit growth period is from April to October. There is a joint at the junction of the ovary peduncle and the fruiting stem. Seeds are flat, linear, 1.4-2.5cm long, 5mm wide, about 2mm thick, rounded at both ends, slightly concave at both ends. [0003] Eucommia ulmoides is a precious and ancient Chinese medicinal material. Scholars from various countries have conducted a lot of research on the chemical comp...

Claims

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Application Information

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IPC IPC(8): A61K36/46A61P39/06A61P3/10
CPCA61K36/46A61P39/06A61P3/10A61K2236/15A61K2236/333
Inventor 欧阳辉
Owner JISHOU UNIVERSITY
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