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Mouthwash effervescent tablet containing lysozyme and preparation method thereof

A technology of lysozyme and blisters, which is applied in the field of effervescent tablets, can solve the problems that the liquid state is not easy to carry and store, and achieve the effect of promoting normal micro-ecological balance, meeting the needs of use, and increasing resistance

Pending Publication Date: 2020-03-06
HAOYIKANG BIOLOGICAL TECH(GUANGZHOU) CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 1. Liquid mouthwash contains a lot of alcoholic liquid;
[0007] 2. The liquid state is not easy to carry and store;

Method used

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  • Mouthwash effervescent tablet containing lysozyme and preparation method thereof
  • Mouthwash effervescent tablet containing lysozyme and preparation method thereof
  • Mouthwash effervescent tablet containing lysozyme and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0046] Prepare tablet according to the formula in Table 1:

[0047] Table I

[0048]

[0049]

[0050]Formulation 1-Formulation 8 mainly studies the effect of the ratio of alkali source to acid source on the use of effervescent tablets, the ratio is 3:1-1:3, of which formula 8 is the control group; the following formula 9-formula 15 mainly The research is the effect of the content of effervescent agent on the use of effervescent tablets, wherein formula 15 is the control group.

[0051] Preparation steps:

[0052] (1) Grind the above-mentioned raw materials except lysozyme respectively, pass through a 160-180 mesh sieve, and take each raw material according to the proportioning ratio, and set aside;

[0053] (2) Add sodium bicarbonate, 50% of the amount of hydroxyethyl cellulose, and 30% of the amount of PEG6000 into the ethanol solution, granulate, dry and pulverize into powder, and pass through a 160-180 mesh sieve to obtain powder A.

[0054] (3) lysozyme, sorbitol...

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Abstract

The invention discloses a mouthwash effervescent tablet containing lysozyme. The effervescent tablet is prepared from the following components in parts by weight: 2000 to 4000 parts of an effervescingagent, 500 to 2000 parts of a filling agent, 50 to 500 parts of lysozyme, 1 to 15 parts of a sweetening agent, 50 to 500 parts of a lubricating agent, 50 to 500 parts of an adhesive, 5 to 400 parts of a freshener, 5 to 150 parts of essence and 5 to 250 parts of other functional additives. The mouthwash prepared by the invention can improve the defense function of a human body, enhance the resistance of beneficial bacteria in the oral cavity to external interference factors, promote the maintenance of the normal microecological balance of the oral cavity, inhibit the propagation of pathogenicbacteria in the oral cavity and reduce various oral cavity problems; and the mouthwash effervescent tablet is convenient to carry and store, can be quickly disintegrated in water to prepare mouthwash,is convenient to use, and can meet the use requirements of business travelers who frequently go on business trips. The invention also relates to a preparation method of the effervescent tablet.

Description

technical field [0001] The invention relates to an effervescent tablet for mouthwash, in particular to a mouthwash effervescent tablet containing lysozyme. The invention also relates to a preparation method of the effervescent tablet. Background technique [0002] Chinese consumers are plagued by oral problems, including tooth decay, bleeding gums, gum inflammation, tooth sensitivity, bad breath and yellow teeth. The Fourth National Oral Epidemiological Survey in 2015 showed that the prevalence of permanent tooth caries among 12-year-old children was 34.5%, an increase of 7.8 percentage points compared with ten years ago. The caries rate of deciduous teeth of 5-year-old children was 70.9%, an increase of 5.8 percentage points compared with ten years ago. The oral cavity of middle-aged people mainly focuses on periodontal health problems, and the detection rate of gingival bleeding is as high as 87.4%. Oral disease is a common and frequently-occurring disease that affects ...

Claims

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Application Information

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IPC IPC(8): A61K8/02A61K8/19A61K8/34A61K8/365A61K8/60A61K8/66A61K8/67A61K8/73A61K8/86A61Q11/00
CPCA61K8/0216A61K8/19A61K8/365A61K8/60A61K8/602A61K8/345A61K8/66A61K8/86A61K8/731A61K8/34A61K8/676A61Q11/00
Inventor 褚夫江徐天生耿帅峰欧阳学琭李婷
Owner HAOYIKANG BIOLOGICAL TECH(GUANGZHOU) CO LTD
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