Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method and application of functionalized graphene modified glassy carbon electrode

A glassy carbon electrode and graphene technology, applied in the direction of material electrochemical variables, material analysis through electromagnetic means, instruments, etc., can solve the problems of slow electron transfer rate, easy adsorption of oxidation products, inaccurate detection results, etc., and achieve good results. reproducible effect

Active Publication Date: 2020-01-10
SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING
View PDF8 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The electrochemical sensor has ultra-high sensitivity and wide detection range for the detection of adrenaline, but the composite sensitive membrane has the disadvantages of slow electron transfer rate and easy adsorption of oxidation products when detecting adrenaline, resulting in inaccurate detection results The problem

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method and application of functionalized graphene modified glassy carbon electrode

Examples

Experimental program
Comparison scheme
Effect test

Embodiment l

[0023] A preparation method for a functionalized graphene-modified glassy carbon electrode, comprising the steps of:

[0024] 1) Pretreatment of glassy carbon electrodes

[0025] The glassy carbon electrodes were sequentially coated with 1.0, 0.3, 0.05 μm Al 2 o 3 The powder was polished to a mirror surface, and then ultrasonically washed 3 times in twice distilled water and absolute ethanol, each time for 3 minutes, N 2 Dry and set aside for use to prepare a pretreated electrode.

[0026] 2) Activation of pretreatment electrodes

[0027] at 1.0 x 10 -3 mol / L K 3 [Fe(CN) 6 ] The pretreated electrode was electrochemically activated by cyclic voltammetry in the solution.

[0028] 3) Preparation of copper-doped γ-ureapropyltriethoxysilane functionalized graphene oxide

[0029] Weigh 1.00g of graphene oxide and dissolve it in 500mL of absolute ethanol, sonicate for 2 hours to obtain a graphene oxide solution, transfer it to a reaction kettle, and then add 0.15g of γ-ureapr...

Embodiment 2

[0033] A preparation method for a functionalized graphene-modified glassy carbon electrode, comprising the steps of:

[0034] 1) Pretreatment of glassy carbon electrodes

[0035] The glassy carbon electrodes were sequentially coated with 1.0, 0.3, 0.05 μm Al 2 o 3 The powder was polished to a mirror surface, and then ultrasonically washed 3 times in twice distilled water and absolute ethanol, each time for 3 minutes, N 2 Dry and set aside for use to prepare a pretreated electrode.

[0036] 2) Activation of pretreatment electrodes

[0037] at 1.0 x 10 -3 mol / L K 3 [Fe(CN) 6 ] The pretreated electrode was electrochemically activated by cyclic voltammetry in the solution.

[0038] 3) Preparation of nickel-doped γ-ureapropyltriethoxysilane functionalized graphene oxide

[0039]Weigh 1.00g of graphene oxide and dissolve it in 500mL of absolute ethanol, sonicate for 2 hours to obtain a graphene oxide solution, transfer it to a reaction kettle, and then add 0.18g of γ-ureapro...

Embodiment 3

[0043] A preparation method for a functionalized graphene-modified glassy carbon electrode, comprising the steps of:

[0044] 1) Pretreatment of glassy carbon electrodes

[0045] The glassy carbon electrodes were sequentially coated with 1.0, 0.3, 0.05 μm Al 2 o 3 The powder was polished to a mirror surface, and then ultrasonically washed 3 times in twice distilled water and absolute ethanol, each time for 3 minutes, N 2 Dry and set aside for use to prepare a pretreated electrode.

[0046] 2) Activation of pretreatment electrodes

[0047] at 1.0 x 10 -3 mol / L K 3 [Fe(CN) 6 ] The pretreated electrode was electrochemically activated by cyclic voltammetry in the solution.

[0048] 3) Preparation of iron-doped γ-ureapropyltriethoxysilane functionalized graphene oxide

[0049] Weigh 1.00g of graphene oxide and dissolve it in 500mL of absolute ethanol, sonicate for 2 hours to obtain a graphene oxide solution, transfer it to a reaction kettle, and then add 0.35g of γ-ureaprop...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a preparation method and application of a functionalized graphene modified glassy carbon electrode. The preparation method comprises the following steps of modifying a surfaceof the polished glassy carbon electrode by adopting a modifier containing metal-doped gamma-ureidopropyltriethoxysilane functionalized graphene oxide with effective concentration after electrochemically activating the polished glassy carbon electrode, thereby obtaining the functionalized graphene modified glassy carbon electrode. The invention further discloses application of the functionalized graphene modified glassy carbon electrode in detecting the concentration of epinephrine in an electrochemical method. The problems that the traditional electrode detection is slow in response, narrow indetection range and low in sensitivity due to the defects that the epinephrine is slow in electron transfer rate on a bare electrode and the oxidation products are easy to adsorb are solved by utilizing the unique electrocatalytic property of graphene oxide. The testing method disclosed by the invention is good in reproducibility and stability, and can be used for measuring the concentration of the epinephrine hydrochloride, and has the features of being fast, sensitive and accurate.

Description

technical field [0001] The invention belongs to the technical field of electrochemical method detection, and in particular relates to a preparation method and application of a functionalized graphene-modified glassy carbon electrode. Background technique [0002] Adrenaline is a catecholamine neurotransmitter, which plays a very important role in the normal activities of the human body, and the level of the content in body fluids will affect the health of the person. Therefore, the concentration detection of epinephrine and its metabolites is very important in drug analysis and clinical diagnosis. At present, a series of methods for detecting the concentration of epinephrine have been developed, such as high performance liquid chromatography, biosensor method, spectrophotometry, chemiluminescence method, fluorescence method, electrochemical method, capillary electrophoresis, etc. [0003] The essence of adrenaline oxidation reaction is electron transfer. Since the epinephr...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N27/327G01N27/30
CPCG01N27/3277G01N27/3278G01N27/308
Inventor 李明田肖丽丽附青山杜鹃蒋琪邹睿夏凡琴
Owner SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com