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Circulation loop for preparing I-125 through reactor irradiation

A technology of I-125 and circulation loop, applied in the field of nuclear chemical industry, can solve problems such as insufficient production process efficiency, achieve the effect of simplifying the structure and ensuring radiation safety

Inactive Publication Date: 2020-01-03
CHINA INSTITUTE OF ATOMIC ENERGY
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Faced with the large domestic application demand, the existing 125 I production process efficiency is far from enough

Method used

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  • Circulation loop for preparing I-125 through reactor irradiation
  • Circulation loop for preparing I-125 through reactor irradiation

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Embodiment Construction

[0026] The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0027] mass production 125 I can utilize reactor thermal neutron irradiation 124 Xe get 125 Xe, 125 Xe decays to produce 125 I. Its nuclear reaction is shown in figure 1 .

[0028] There are also two secondary nuclear reactions in the irradiation preparation process:

[0029] Secondary nuclear reaction 1: 125 I(n,γ) 126 I(n,γ) 127 I

[0030] Secondary nuclear reaction 2: 125 Xe(n,γ) 126 Xe(n,γ) 127 Xe

[0031] 125 I has a larger thermal neutron cross-section of 894b, which will produce a certain amount of 126 I, produced by 126 I mainly have strong gamma rays with an energy of 666KeV, and also contain beta + and beta － Rays. In order to avoid the impact of impurities produced by secondary nuclear reactions on product quality, it is necessary to irradiate for a certain period of time 125 Xe shifts out of the heap, causing it to dec...

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Abstract

The invention discloses a circulation loop for preparing I-125 through reactor irradiation. The circulation loop comprises a loop pipeline, an irradiation part, a recovery device, a gas blocking device, a raw material gas cylinder, a tail gas purification device and a molecular pump, wherein an electromagnetic valve is arranged on the loop pipeline so as to carry out node control; the irradiationpart, the recovery device, the gas blocking device, the raw material gas cylinder, the tail gas purification device and the molecular pump are all connected to the loop pipeline; and the irradiation part is arranged in a reactor. The beneficial effects of the invention are as follows: the loop system is used for controlling the amount of the raw material gas filled in the irradiation bottle, so that the preparation yield of <125>I can be accurately controlled, and the automatic control effects of high irradiation efficiency, good irradiation safety of thecirculation loop, little radioactive pollution and little radiation injury to operators during <125>I reactor irradiation production are achieved. The input amount of the raw material target gas can be determined according to the yield requirement, and continuous circulation and intermittent circulation can be carried out according to the yield requirement.

Description

technical field [0001] The invention relates to the field of nuclear chemical industry, in particular to a circulation loop for preparing I-125 by reactor irradiation. Background technique [0002] 125 I is a long half-life (T 1 / 2 =59.7d) radioactive isotope of iodine, which releases low-energy γ-rays (27KeV, X-rays) through electron capture. because 125 I Longer half-life, low gamma ray energy, no beta - Radiation is widely used in nuclear medicine clinical diagnosis, biomedical research and tumor brachytherapy (X-ray seed source). Especially in recent years, 125 The medical application of I seed sources has been developed very rapidly. 125 I seed source can be used for brachytherapy of various malignant tumors (head and neck, digestive system, chest and urinary system tumors, etc.), 125 I continuously releases radiation over a short distance, so that the tumor tissue is killed to the maximum extent, while the normal tissue is not damaged or slightly damaged, so as t...

Claims

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Application Information

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IPC IPC(8): G21G1/00G21G1/02
CPCG21G1/001G21G1/02G21G2001/0063
Inventor 于宁文罗志福邓新荣向学琴
Owner CHINA INSTITUTE OF ATOMIC ENERGY
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