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Traditional Chinese medicine compound for treat gout and preparation method and application of compound

A compound and gout technology, applied in the directions of drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as large side effects and easy recurrence, and achieve a good effect on gouty arthritis and a good effect on the treatment of gout. Effect

Pending Publication Date: 2019-11-15
XIAMEN HUAXIA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Conventional medicines such as non-steroidal anti-inflammatory drugs, colchicine, glucocorticoids, etc., are currently clinically used in the treatment of gout by Western medicine. The curative effect is reliable but the side effects are large, and they are prone to relapse after drug withdrawal, which has certain limitations and dependence (Cao Qijiang et al., Research progress of new drugs for the treatment of gout, Guangdong Medicine, 2019, 40(10): 1497-1500)

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] prescription:

[0028] Traditional Chinese medicine compound for treating gout: Walnut shell 20g, Salvia 10g, Codonopsis 10g, Astragalus 12g, Cornus 9g, Rehmannia glutinosa 9g, Alisma 9g, Plantago 12g (package), Hawthorn 9g, Motherwort 12g, Oldenlandia diffusa 9g , Hemp kernels 20g.

[0029] The above prescription is 1 dose, 1 dose per day, 1 dose divided into 3 times to get the decoction, the specific method is as follows:

[0030] Take 1 dose of the above-mentioned anti-fatigue Chinese medicine compound, add 400~500ml of water, soak for 20~30min, decoct for 15~30min until the liquid volume is 200ml, get the first decoction liquid, take it; add 300~400ml water for medicine residue Decocting for 15-20 minutes until the liquid volume is 150ml to obtain the second decoction liquid, take it; add 300ml of water again for the medicinal residue, and decoct 15-20min until the liquid volume is 150ml to obtain the third decoction liquid, continue Taking.

[0031] According to needs, t...

Embodiment 2

[0033] prescription:

[0034] Traditional Chinese medicine compound for treating gout: Walnut shell 20g, Salvia 9g, Codonopsis 12g, Astragalus 10g, Cornus 9g, Rehmannia glutinosa 9g, Alisma 9g, Plantago 20g (package), Hawthorn 9g, Motherwort 15g, Oldenlandia diffusa 12g , Hemp seed 12g.

[0035] The above prescription is 1 dose. Take 1 dose a day, and take 1 dose after three times of decoction to obtain the decoction. The specific method is the same as in Example 1.

[0036] According to needs, the above prescriptions can be prepared into clinically acceptable dosage forms such as oral liquids, granules, decoctions, etc. The preparation method is not limited to the preparation method described in Example 1.

Embodiment 3

[0038] prescription:

[0039] Traditional Chinese medicine compound for treating gout: Walnut shell 15g, Salvia 12g, Codonopsis 10g, Astragalus 15g, Cornus 9g, Rehmannia glutinosa 12g, Alisma 9g, Plantago 12g (package), Hawthorn 9g, Motherwort 15g, Hedyotis diffusa 12g , Hemp seed 12g.

[0040] The above prescription is 1 dose. Take 1 dose a day, and take 1 dose after three times of decoction to obtain the decoction. The specific method is the same as in Example 1.

[0041] According to needs, the above prescriptions can be prepared into clinically acceptable dosage forms such as oral liquids, granules, decoctions, etc. The preparation method is not limited to the preparation method described in Example 1.

[0042] Specific cases are given below.

[0043] 1. Li Moumou, male, 62 years old, first diagnosed on May 6, 2010. Three months ago, the patient went to the hospital for swelling, heat and pain in the first metatarsophalangeal joint of his left foot. The blood uric acid was 592.2 ...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine compound for treat gout and a preparation method and application of the compound and relates to traditional Chinese medicine compounds. The traditional Chinese medicine compound for treat gout is prepared from, by mass, 10-30 g of walnut shells, 6-12 g of radix salviae miltiorrhizae, 6-12 g of radix codcnopsitis pilosulas, 6-15 g of radix astragali, 6-12 g of fructus corni, 6-12 g of radix rehmanniae preparata, 6-15 g of rhizoma alismatis, 6-12 g of semen plantaginis, 6-12 g of fructus crataegi, 9-15 g of motherwort herbs, 6-12 g of spreading hedyotis herbs and 9-12 g of fructus cannabis. The traditional Chinese medicine compound for treat gout can be applied to preparation for a medicine for treating gout. The dosage form of the traditional Chinese medicine compound for treat gout can be decoction or granules or tablets and the like. The traditional Chinese medicine compound for treat gout has the functions of tonifying the kidney and spleen, clearing away heat, removing dampness, reducing phlegm and dissipating blood stasis and achieves simultaneous treatment of principal and subordinate symptoms, and through clinical practice, it is proved that the compound has a good function of treating gout.

Description

Technical field [0001] The invention relates to a Chinese medicine compound, in particular to a Chinese medicine compound for treating gout, and a preparation method and application thereof. Background technique [0002] Gout is a systemic disease in which the blood uric acid concentration caused by the disorder of purine metabolism and (or) excessive uric acid production and (or) decreased uric acid excretion exceeds the normal range, resulting in urate deposition in the body and tissue damage. The clinical manifestations are hyperuricemia and the resulting gouty acuteness, chronic arthritis, and tophi. In severe cases, it can cause joint deformities, renal insufficiency and other important organ damage. [0003] Hyperuricemia is the most important biochemical basis for gout. Hyperuricemia (HUA) is a chronic metabolic disease caused by purine metabolism disorder. The overall epidemiology of HUA shows a trend of increasing year by year, which may be related to people's eating hab...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61P19/06
CPCA61K36/52A61K36/537A61K36/344A61K36/481A61K36/40A61K36/804A61K36/884A61K36/68A61K36/734A61K36/533A61K36/748A61K36/60A61P19/06A61K2236/331A61K2236/39A61K2300/00Y02A50/30
Inventor 林贤宗谢增鸿林丽丽苏思颖
Owner XIAMEN HUAXIA UNIV
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