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Composition for promoting transdermal absorption and preparation method thereof

A composition and transdermal technology, which is applied in the direction of drug combination, effective ingredients of hydroxyl compounds, medical preparations containing active ingredients, etc., can solve the problems of reduced use effect and failure of essential ingredients, and achieve strong emulsifying ability and improved stability Non-toxic and eye-irritating effect

Active Publication Date: 2021-09-24
郑州市新视明科技工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Emulsify the above ingredients evenly in an emulsifying tank, fill them into a molded eye patch, and make a finished product. This invention is applied to the eyes so that lutein can be directly absorbed from the skin of the eyes, and sodium hyaluronate is added to the formula as a The transdermal absorption accelerator improves the transdermal absorption rate of lutein. At the same time, ingredients with the functions of promoting blood circulation, dispelling wind and clearing heat, calming the liver and improving eyesight are added to the formula, and moisturizing ingredients are added to treat pseudomyopia. , prevention and treatment of dry eye disease, cataract, macular degeneration, eye protection and other multiple effects, but because it does not use emulsifiers, emulsification requires a higher temperature (80 ° C), resulting in the failure of many ingredients in the emulsion. , the use effect is reduced

Method used

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  • Composition for promoting transdermal absorption and preparation method thereof
  • Composition for promoting transdermal absorption and preparation method thereof
  • Composition for promoting transdermal absorption and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A composition for promoting transdermal absorption, which is made of the following raw materials: 5g of dendrobium, 33g of wild chrysanthemum, 6g of chrysanthemum, 8g of wolfberry, 4g of mulberry leaf, 6g of Codonopsis pilosula, 5g of perilla seed, 32g of Tribulus terrestris, 5g of calamus calamus, Angelica 6g, Dilong 7g, Ruin 6g, Mountain Silver Flower 4g, Safflower 6g, Rose 4g, Prunella vulgaris 6g, Salvia miltiorrhiza 24g, Phellodendron 34g, Coptidis 26g, paeonol extract 0.6g, Houttuynia cordata 26g, Green tea extract 14g, grape seed extract 6g, alfalfa extract 36g, iris flower extract 34g, xuanming powder 26g, pearl powder 23g, borneol 2g, menthol 3g, camellia seed oil 56g, linseed oil 28g, flax 35g of seed extract, 5g of silk protein, 126g of glycerin, 13g of 1,2-pentanediol, 6g of p-hydroxyacetophenone, 22g of propylene glycol and 3500g of water.

Embodiment 2

[0037] A composition for promoting transdermal absorption, made of the following raw materials: Dendrobium 8g, wild chrysanthemum 31g, chrysanthemum 8g, wolfberry 5g, mulberry leaves 3g, Codonopsis 1g, perilla seeds 6g, Tribulus terrestris 35g, calamus calamus 6g, 3g angelica, 4g earthworm, 2g rutabaga, 1g mountain silver flower, 2g safflower, 8g rose, 2g prunella vulgaris, 27g salvia miltiorrhiza, 36g phellodendron cortex, 22g berberine, 0.9g paeonol extract, 23g houttuynia cordata, Green tea extract 15g, grape seed extract 3g, alfalfa extract 33g, iris flower extract 36g, xuanming powder 23g, pearl powder 19g, borneol 1g, menthol 4g, camellia seed oil 64g, linseed oil 32g, flax 32g of seed extract, 5g of silk protein, 138g of glycerin, 12g of 1,2-pentanediol, 8g of p-hydroxyacetophenone, 28g of propylene glycol and 3500g of water.

Embodiment 3

[0039] A composition for promoting transdermal absorption, which is made of the following raw materials: 2g of dendrobium, 30g of wild chrysanthemum, 7g of chrysanthemum, 6g of wolfberry, 3.5g of mulberry leaf, 6g of codonopsis, 9g of perilla seed, 36g of tribulus, and 3g of calamus , angelica 8g, earthworm 4g, rutabaga 9g, mountain silver flower 3g, safflower 4g, rose 5g, Prunella vulgaris 7g, salvia miltiorrhiza 25g, cork 38g, berberine 22g, paeonol extract 0.9g, houttuynia cordata 28g , Green tea extract 11g, grape seed extract 4g, alfalfa extract 32g, iris flower extract 39g, xuanming powder 26g, pearl powder 35g, borneol 1.6g, menthol 3g, camellia seed oil 76g, linseed oil 38g , linseed extract 36g, silk protein 5g, glycerin 126g, 1,2-pentanediol 13g, p-hydroxyacetophenone 6g, propylene glycol 22g and water 3500g.

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Abstract

The invention relates to the field of preparation of eye patches, in particular to a composition for promoting transdermal absorption of eye patches and a preparation method thereof. Seeds, Tribulus terrestris, Acorus chinensis, Angelica sinensis, Dilong, Rui Ren, Silver Flower, Safflower, Rose, Prunella, Salvia, Treats, Coptis, Paeonol Extract, Houttuynia Cordata, Green Tea Extract, Grape Seed Extract, Alfalfa Extract, Iris Flower Extract, Xuanming Powder, Pearl Powder, Synthetic Borneol, Menthol, Camellia Seed Oil, Flaxseed Oil, Flaxseed Extract, Silk Protein, Glycerin, 1,2-Pentane Alcohol, p-hydroxyacetophenone, propylene glycol and water are prepared through extraction and emulsification process, which can effectively promote the absorption of the active ingredients of the eye patch.

Description

technical field [0001] The invention relates to the field of preparation of eye patches, in particular to a composition for promoting transdermal absorption for eye patches and a preparation method thereof. Background technique [0002] At present, most of the eye patches on the market are water-based, because the intact skin of the human body can only absorb a small amount of water and trace gases, and water-soluble substances are not easily absorbed, so there is a partial waste of active ingredients in the water-based eye patches; and the water-based eye patches The patch evaporates quickly, the use time is not long, and the eye patch can no longer adhere to the eyes after losing moisture, and the applicability of the eye patch is reduced; at the same time, the liquid eye patch has strong fluidity, and the user will stick to the eye Part of the eye patch solution flowed out onto the face; the water-based Chinese medicine health care eye patch is prepared from traditional C...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61K9/107A61K47/44A61P27/02A61K31/045A61K31/12A61K33/04A61K35/618A61K35/62
CPCA61K9/0048A61K9/107A61K31/045A61K31/12A61K33/04A61K35/618A61K35/62A61K36/185A61K36/232A61K36/286A61K36/287A61K36/344A61K36/355A61K36/48A61K36/535A61K36/536A61K36/537A61K36/605A61K36/718A61K36/73A61K36/738A61K36/756A61K36/78A61K36/815A61K36/82A61K36/87A61K36/88A61K36/888A61K36/8984A61K47/44A61P27/02A61K2300/00
Inventor 张秋霞
Owner 郑州市新视明科技工程有限公司
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