Lactobacillus rhamnosus capable of reducing uric acid

A technology of Lactobacillus rhamnosus and blood uric acid, which is applied in the field of microorganisms, can solve problems such as increasing human blood uric acid, and achieve the effects of lowering uric acid levels, lowering blood uric acid levels, and inhibiting intake.

Active Publication Date: 2019-08-30
HANGZHOU WAHAHA TECH +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the decomposed products are free purine bases, which still have the risk of being converted into uric acid after being absorbed into the human body, increasing blood uric acid in the human body

Method used

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  • Lactobacillus rhamnosus capable of reducing uric acid
  • Lactobacillus rhamnosus capable of reducing uric acid
  • Lactobacillus rhamnosus capable of reducing uric acid

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Embodiment

[0024] A strain of Lactobacillus rhamnosus that can reduce blood uric acid was screened by the inventor from traditional yogurt collected in the Inner Mongolia Autonomous Region of my country in the previous work. It was identified as Lactobacillus rhamnosus and named as 1155 strain. It was preserved in the General Microorganism Culture Collection Center of China Microbiology Culture Collection Management Committee on January 4, 2016, and the microorganism preservation number is CGMCC NO.11955. The biological properties of the strain are as follows:

[0025] Morphological characteristics: In MRS agar medium, the growth form is milky white colony, opaque, round, smooth and moist surface, neat edges, and raised in the center. Gram staining was typically positive, and under the microscope the cells were short rod-shaped, without flagella, spore-forming, and motionless.

[0026] Culture characteristics: The optimum growth temperature is 37°C, facultatively anaerobic, and grown in...

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Abstract

The invention relates to the field of microorganisms, and discloses lactobacillus rhamnosus capable of reducing uric acid. The lactobacillus rhamnosus is named as 1155, is preserved in microbial culture collection management committee of China general microbiological culture collection on 4th, January, 2016, with the microbial preservation number being CGMCC NO.11955; and the preservation organization address is yard No.3, west Beichen road, Chaoyang district, Beijing City, and the microbial classification name is lactobacillus rhamnosus. According to strains disclosed by the invention, the content of the uric acid can be effectively reduced, discharging of uric acid in the body from an intestinal tract also can be promoted, intake of exogenous purine substances also can be reduced, and auric acid level of an organism can be controlled more effectively.

Description

technical field [0001] The invention relates to the field of microorganisms, in particular to a strain of Lactobacillus rhamnosus capable of reducing blood uric acid. Background technique [0002] Hyperuricemia is a metabolic disease caused by purine metabolism disorders, and its main feature is that the uric acid in the circulating blood is higher than the normal level for a long time. The number of patients with hyperuricemia in my country has reached 170 million, of which more than 80 million patients with gout, and are increasing rapidly at an annual growth rate of 9.7%. Long-term high uric acid levels will have a series of adverse consequences on blood vessels, heart, and kidneys, and increase the risk of cardiovascular and cerebrovascular diseases, hypertension, diabetes, and kidney diseases. [0003] Although the drugs for treating hyperuricemia have obvious curative effects, most of them have side effects of varying degrees, such as severe allergic reactions, gastro...

Claims

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Application Information

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IPC IPC(8): C12N1/20A61K35/747A61P19/06A23L33/135C12R1/225
CPCA61K35/747A61P19/06A23L33/135A23V2002/00C12R2001/225C12N1/205A23V2400/175A23V2200/30
Inventor 孙盛朱珺陈苏李言郡陈作国陈丽娥周晴晴
Owner HANGZHOU WAHAHA TECH
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