Externally applied medicinal composition for treating neonatal dermatosis, preparation method and use method thereof
A technology of externally used drugs and compositions, applied in the direction of drug combinations, skin diseases, medical preparations containing active ingredients, etc., can solve the problems of not advising to use it on newborns, easy to relapse, unsuitable for newborns, etc., to reduce resistance The production of drug strains, high cure rate and effective rate, and no adverse reactions
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Embodiment 1
[0031] The external pharmaceutical composition for treating neonatal skin diseases consists of the following raw materials in parts by mass: 20 g of sophora flavescens, 18 g of purslane, 15 g of honeysuckle, and 10 g of white ox gallbladder.
[0032] The preparation method comprises the following steps: weighing sophora flavescens, purslane, honeysuckle and white ox gallbladder, grinding and crushing, the particle size range is 40-50 mesh, soaking in pure water for 30 minutes; then, adding pure water to make up the system to 500ml, simmering Decoct for 30-40 minutes to obtain about 250ml of liquid medicine; cool down to room temperature, subpackage, and set aside.
Embodiment 2
[0034] The external pharmaceutical composition for treating neonatal dermatosis is composed of the following raw materials in parts by mass: 30g of sophora flavescens, 27g of purslane, 25g of honeysuckle, and 20g of white ox gallbladder.
[0035] The preparation method is the same as in Example 1.
Embodiment 3
[0037] The pharmaceutical composition for external use for treating neonatal skin disease consists of the following raw materials in parts by mass: 20 g of sophora flavescens, 20 g of purslane, 20 g of honeysuckle, and 10 g of white ox gallbladder.
[0038] The preparation method is the same as in Example 1.
[0039] Animal experiment-rash model (adopting embodiment 1 formula)
[0040] 1. Animals
[0041] 48 clean-grade KM mice, half male and half male, 25-30 g each, were purchased from Qingdao Animal Center. During the experiment, all mice were normally fed with feed and water without special experimental requirements, the growth environment temperature was 22±2 degrees, the humidity was 50-60%, and the circadian rhythm was 12-12 hours.
[0042] 2. Grouping
[0043] 48 mice were weighed after feeding for 1 week to ensure that there was no statistical difference in weight change, and then they were randomly divided into 6 groups, which were blank control group, model group,...
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