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Semi-automatic immunofluorescence analysis system

An immunofluorescence and analysis system technology, which is applied in the direction of material analysis, analysis of materials, fluorescence/phosphorescence, etc. by optical means, which can solve the problem that the sensitivity of the instrument cannot reach the microfluidic fluorescence immunity, and improve the detection sensitivity and accuracy. , exquisite structure, convenient assembly effect

Active Publication Date: 2019-07-23
四川微康朴澜医疗科技有限责任公司
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Problems solved by technology

The sensitivity of the instruments used in the existing immunochromatography methods cannot meet the requirements of microfluidic fluorescence immunoassays

Method used

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  • Semi-automatic immunofluorescence analysis system
  • Semi-automatic immunofluorescence analysis system
  • Semi-automatic immunofluorescence analysis system

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Embodiment Construction

[0055] Attached below Figure 1-11 The present invention will be further described in detail with reference to specific embodiments. However, it should not be understood that the scope of the above subject matter of the present invention is limited to the following embodiments, and all technologies realized based on the content of the present invention belong to the scope of the present invention.

[0056] The design concept of the present invention is: traditional copolymerization optical system ( figure 2 Shown is a typical traditional optical path structure) The reason for the low detection sensitivity of weak fluorescence signals is that the amount of excited fluorescence collected by the optical system is too small, so it is necessary to improve the ability of the optical system to collect fluorescence. When the diameter of the collimating convex lens in the detection light path is constant, the closer the distance between the convex lens and the fluorescent light-emitt...

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Abstract

The invention provides a semi-automatic immunofluorescence analysis system, comprising a test card conveying device, an optical path structure, and an optical analysis device comprising the optical path structure. The semi-automatic immunofluorescence analysis system provided by the invention has high sensitivity and accuracy. By shortening the distance between a convex lens and a detection area,the fluorescence within a larger angle range can enter a detection optical path, thereby improving the detection sensitivity and accuracy of the system. The structure is exquisite. The semi-automaticimmunofluorescence analysis system provided by the invention has the advantages of compact structure, good optical sealing property, high reliability, convenient assembly, and capability of realizinghigh efficiency detection at a low cost. Semi-automatic accurate monitoring is achieved, and the gap in the field is filled.

Description

technical field [0001] The invention relates to the technical field of optical analysis, in particular to a semi-automatic immunofluorescence analysis system. Background technique [0002] A microfluidic chip is a system that manipulates the flow of a small volume of fluid in a small channel. It can realize the preparation, reaction, and separation of samples and reagents through capillary action and centrifugation. Realize the processes of adding samples, mixing, and reacting that can only be realized by large-scale equipment, and finally cooperate with corresponding equipment to realize signal detection. [0003] Immunofluorescence is based on the principle of antigen-antibody reaction. First, the known antigen or antibody is labeled with fluorescein to make a fluorescent marker, and then this fluorescent antibody (or antigen) is used to react with the antigen (or antibody) in the sample to be tested. Formation of antigen-antibody complexes. The formed antigen-antibody c...

Claims

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Application Information

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IPC IPC(8): G01N21/64G01N21/01G01N35/00
CPCG01N21/01G01N21/6402G01N21/6486G01N35/00584
Inventor 唐勇廖政潘颖
Owner 四川微康朴澜医疗科技有限责任公司
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