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Bionic repair method for bone tumors

A repair method and bone tumor technology, applied in design optimization/simulation, image enhancement, instrumentation, etc., can solve problems such as damage to the donor site, rejection, high infection rate, and limited bone extraction

Active Publication Date: 2019-07-12
NANJING UNIV OF AERONAUTICS & ASTRONAUTICS +1
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Problems solved by technology

Autologous bone grafting is the gold standard for bone repair, but the source and amount of bone taken are limited and cause damage to the bone donor area; although allogeneic bone grafting is not limited by the source and shape, the postoperative rejection and infection rates are relatively high. high
Artificial bone with certain biocompatibility manufactured by traditional machining is widely used in the field of bone repair, but there are usually mismatching problems in terms of structural shape and mechanical properties

Method used

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  • Bionic repair method for bone tumors
  • Bionic repair method for bone tumors
  • Bionic repair method for bone tumors

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Embodiment Construction

[0050] In view of the uncertainty of the location, type, and size of bone tumors, 3D printing-oriented bone tumor repair needs to be designed with precise digital repair plans before surgery, with the design goal of approaching the external shape, internal structure, and mechanical properties of autogenous bone. And ensure the manufacturability of the repair model built.

[0051] In the embodiment of the present invention, for the image data from different patients, the tumor image data of the patient is firstly segmented with semantic characteristics, the area corresponding to the target bone tissue is accurately segmented and extracted, and the three-dimensional reconstruction of the bone surface model based on the envelope and approximation is carried out. Algorithm to achieve accurate reconstruction of segmentation results; for bone loss caused by bone tumors, according to the biomedical characteristics of the skeletal system, build a bionic constraint set and restoration a...

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Abstract

The invention discloses a bionic repair method for bone tumors, and belongs to the computer-aided biomedical engineering, and the method comprises the steps: carrying out segmentation with semantic characteristics on tumor image data of a patient, accurately segmenting and extracting an area corresponding to a target bone tissue, and realizing accurate reconstruction of a segmentation result basedon an envelope and approximation bone surface model three-dimensional reconstruction algorithm; constructing a bionic constraint set and a recovery framework for bone loss caused by bone tumors according to biomedical characteristics of a bone system, realizing accurate recovery of a bone loss form, and designing a constrained free form internal fixation prosthesis based on a bone loss form recovery result; designing an internal bionic porous scaffold structure with good mechanical property and machinability according to the information characteristics of the classified bone area and in combination with a skeleton kinematic mechanical analysis result; and finally, generating an integrated implant prosthesis through fusion, so that a personalized and accurate bone tumor repair system is realized.

Description

technical field [0001] The invention belongs to the field of computer-aided biomedical engineering, and in particular relates to a bionic repair method for bone tumors. Background technique [0002] Bone loss caused by tumor resection is one of the important factors leading to loss of skeletal function. For local bone loss, there are mainly two methods of transplantation and repair: biological bone (including: autologous bone and allogeneic bone) and artificial bone. Autologous bone grafting is the gold standard for bone repair, but the source and amount of bone taken are limited and cause damage to the bone donor site; although allogeneic bone grafting is not limited by the source and shape, the postoperative rejection and infection rates are relatively high. high. Artificial bones with certain biocompatibility manufactured by traditional machining are widely used in the field of bone repair, but there are usually mismatching problems in terms of structural shape and mecha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F17/50G06T7/11G06T17/00
CPCG06T17/00G06T7/11G06T2207/20081G06T2207/30008G06T2207/30096G06F30/23Y02T10/40
Inventor 袁天然汪俊罗春英侯志伟
Owner NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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