Traditional Chinese medicine composition for treating advanced non-small cell lung cancer and preparing method and application thereof
A technology for non-small cell lung cancer and composition, which can be used in drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., and can solve problems such as poor curative effect, difficulty in early diagnosis and treatment of lung cancer, and difficulty in obtaining curative effects.
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[0037] The present invention also provides a preparation method of the Chinese medicine composition, comprising the following steps: mixing the raw materials according to the weight parts to obtain a Chinese medicine mixture; mixing the Chinese medicine mixture and water at a mass ratio of 1:6-8 Mixing, decocting, and filtering to obtain a Chinese medicine liquid; concentrating the Chinese medicine liquid to a relative density of 1.30-1.35 extract, drying under reduced pressure, and pulverizing into a Chinese medicine composition powder.
[0038] In the preparation method of the present invention, the decoction is preferably carried out under natural pressure, and the temperature of the decoction is preferably 70-100°C, more preferably 100°C. The decocting in the present invention is preferably carried out 2 to 3 times, and the time of each decocting is 1.8 to 2.5 hours, more preferably 2 hours. In the present invention, after each decoction, the decocted filter residue is col...
Embodiment 1
[0043] Weigh 5g ginseng, 20g astragalus, 5g Radix Radix, 5g Ophiopogon japonicus, 5g tangerine peel, 5g Pinellia, 5g Fritillaria, 5g Angelica, 3g Sanqi, 10g Scutellaria barbata, 20g Hedyotis diffusa, 10g Poria cocos, Atractylodes macrocephala 5g, Fritillaria 5g, Coix Seed 20g, Aster 5g, Baibu 5g, Bellflower 5g, Radix Licorice 5g, add 6 times the amount of water, decoct 3 times under natural pressure, 2 hours each time, filter the decoction, Combine the filtrates, concentrate to a relative density of 1.20-1.25 (60°C) extract, add appropriate amount of auxiliary materials, make soft materials, sieve, dry, and make granules. The content of active ingredients in the granules is ginsenoside Rg1 and ginsenoside The total content of Re is 0.03%, the content of ginsenoside Rb1 is 0.015%, and the content of astragaloside IV is 0.14%.
Embodiment 2
[0045] Weigh 10g of ginseng, 30g of astragalus, 10g of sand ginseng, 10g of radix japonicus, 10g of tangerine peel, 10g of pinellia, 10g of fritillaria, 10g of angelica, 5g of notoginseng, 15g of Scutellaria barbata, 30g of Hedyotis diffusa, 15g of poria, and Atractylodes macrocephala. 10g, Fritillaria 10g, Coix Seed 30g, Aster 10g, Baibu 10g, Campanulaceae 10g, Roasted Licorice 10g, add 7 times the amount of water, decoct 3 times under natural pressure, 2 hours each time, filter the decoction, Combine the filtrates, concentrate to a relative density of 1.30-1.35 (80°C) extract, dry under reduced pressure, and grind into a fine powder. Auxiliary materials are added to form tablets, and the active ingredient content is 0.03% of ginsenoside Rg1 and ginsenoside Re, 0.016% of ginsenoside Rb1 and 0.15% of astragaloside IV.
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