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A kind of composition containing ashwagandha and application thereof

A composition, technology of withaferin, applied in the field of medicine

Active Publication Date: 2020-06-09
PEKING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, only a small percentage of people are able to maintain long-term weight loss by restricting diet and exercise. In addition, despite the obvious benefits of surgical treatment, the risks of surgery are still prohibitive for many people. Therefore, the difficulty of losing weight has led to increased attention to other treatment avenues , especially pharmacological interventions and treatments

Method used

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  • A kind of composition containing ashwagandha and application thereof
  • A kind of composition containing ashwagandha and application thereof
  • A kind of composition containing ashwagandha and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Composition containing 1 mg of topiramate and 1 μg of withaferin A.

Embodiment 2

[0040] Composition containing 25 mg of topiramate and 1 μg of withaferin A.

Embodiment 3

[0042] A composition containing 20 mg of topiramate and 1 μg of withaferin A.

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Abstract

The invention provides a composition containing withaferin A, and relates to the technical field of medicines. The composition comprises topiramate and the withaferin A in a mass ratio of (1-25)*10<3>:1. Through the combined application of the topiramate and the withaferin A, the using amount of the topiramate and the withaferin A can be reduced, the side effects of the topiramate and the withaferin A can be obviously reduced, and the effects of reducing the body weight, improving the insulin sensitivity and optimizing the lipid metabolism more significantly can be achieved. The composition can still achieve the effects of significantly reducing the body weight, improving the insulin sensitivity and optimizing the lipid metabolism when the dosage is halved.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a composition containing withaferin A and its application. Background technique [0002] With the continuous improvement of people's living standards, obesity and related diseases such as diabetes, hyperlipidemia, fatty liver, cardiovascular and cerebrovascular diseases, etc., which were previously common in western developed countries and related to energy metabolism, are now becoming more and more important. An important disease that threatens the health of the Chinese population. In addition, obesity is a risk factor for cancers, especially colon, rectal, prostate, breast, uterine and cervical cancers. According to statistics, the incidence rates of overweight and obesity among Chinese adults are 30.6% and 12.0% respectively. [0003] Metabolic syndrome is a group of clinical syndromes with central obesity, hyperglycemia, hyperlipidemia, and hypertension, which seriously af...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/585A61K31/7048A61P3/00A61P3/10A61P3/06A61P1/16A61P3/04
CPCA61K31/585A61K31/7048A61P1/16A61P3/00A61P3/04A61P3/06A61P3/10A61K2300/00
Inventor 郑瑞茂王炳蔚王俊博苏志洁刘佳瑞
Owner PEKING UNIV
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