A bionic moisturizing model and its evaluation method

A technology of models and bionic membranes, which is applied in measuring devices, material weighing, and material absorption weighing, etc. It can solve problems such as unsuitable moisturizing system, difficulty in building models, individual differences, and difficult operation time periods in experiments.

Active Publication Date: 2022-02-11
GUANGDONG SHUNFENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the objective evaluation method also has its application limitations, because it is difficult to construct various expected models and problems such as individual differences, experimental difficulty, operation time period, etc., making it not suitable for the experimental research of moisturizing system screening, but more suitable for In the test evaluation as a sample

Method used

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  • A bionic moisturizing model and its evaluation method
  • A bionic moisturizing model and its evaluation method
  • A bionic moisturizing model and its evaluation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1: Construction of the bionic moisturizing model and its evaluation method according to the present invention

[0024] 1. Preparation of infiltrating moisturizer

[0025] According to the following mass percentages, weigh each component respectively:

[0026]

[0027] Take purified water, add sodium hyaluronate, heat and stir until it is completely dissolved; then add betaine, heat and stir until it is completely dissolved; after cooling down to room temperature, add sodium pyrrolidone carboxylate, and stir evenly to obtain the infiltration moisturizer .

[0028] 2. The test layer is treated with an infiltration moisturizer

[0029] Take several pieces of circular rapid quantitative filter paper with a diameter of 3-4cm, and place them in a circular container with an inner diameter of 3-4cm respectively. After each filter paper is infiltrated with 2.0g of infiltration and humectant, take it out and weigh it accurately, and record it as M 0 , then put it...

Embodiment 2

[0046] Example 2: Evaluation of moisturizing agent

[0047] 1. Preparation of moisturizer

[0048] According to the formula shown in the following table 1, each component was weighed respectively:

[0049] The formula of table 1 humectant

[0050]

[0051] Preparation of moisturizing agent 1: Take glycerin, add sodium hyaluronate, stir evenly, add purified water, heat and stir until completely dissolved; then add serine, heat and stir until completely dissolved, cool to room temperature, and obtain.

[0052] Preparation of moisturizing agent 2: Take purified water, add sodium hyaluronate, heat and stir until completely dissolved; then add betaine and serine, heat and stir until completely dissolved, cool to room temperature, and obtain.

[0053] Preparation of moisturizing agent 3: Take purified water, add sodium hyaluronate, heat and stir until completely dissolved; then add sodium pyrrolidone carboxylate and serine, heat and stir until completely dissolved, cool to room...

Embodiment 3

[0059] Embodiment three: evaluation of cream

[0060] 1. Preparation of cream

[0061] According to the formula shown in the following table 3, each component was weighed respectively:

[0062] The formula of table 3 cream

[0063]

[0064]

[0065] Preparation of cream:

[0066] ① Take caprylic / capric triglyceride, grape seed oil, polydimethylsiloxane, cetearyl alcohol cetearyl alcohol, cetearyl glucoside, 2,6-di-tert-butyl p- Cresol, stir and heat to about 100°C to dissolve it completely, keep it warm for 15 minutes, stir and cool down to about 75±2°C, set aside;

[0067] ② Take purified water, add glycerin, allantoin, sodium stearyl glutamate, and disodium EDTA, stir and heat to about 75 ± 2°C, then add the solution prepared in item "①", stir and emulsify for 10 minutes;

[0068] ③Stir and cool down to about 45±2°C, add phenoxyethanol under stirring, continue stirring for 5 minutes, turn on the homogenizer for 5 minutes, stir and cool down to below 38°C, and disch...

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Abstract

The invention discloses a bionic moisturizing model and an evaluation method thereof, a constant temperature box, a water tank placed in the constant temperature box, and a bionic membrane component placed above the water tank; the bionic membrane component includes a test layer and a bionic membrane. The bionic moisturizing model of the present invention can simulate biological skin, has a moisturizing effect test conclusion consistent with the biological skin model, and can perform quantitative evaluation on the product to be tested, and can be used to study the influence of different components on moisturizing effect and quantify Evaluate it accurately, provide data support for formula design of moisturizing and emollient products, and apply it to guide formula screening, and provide faster screening methods and theoretical support for product formula design.

Description

technical field [0001] The invention relates to a bionic moisturizing model and an evaluation method thereof, belonging to the technical field of cosmetics. Background technique [0002] Skin moisturizing is the most basic function of skin care cosmetics and skin care products. The so-called moisturizing is to maintain the moisture in the skin by preventing the moisture loss in the skin and absorbing the moisture in the external environment. With the wide use of various moisturizing cosmetics, how to objectively evaluate and design the moisturizing properties of cosmetics has become an urgent problem for formulation engineers to solve. At present, there are mainly human subjective evaluation method and objective evaluation method for the evaluation of skin moisturizing function. The subjective evaluation method requires evaluators to have considerable experience, and has poor repeatability and low accuracy; the objective evaluation method is mainly based on TEWL (transepid...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N5/02
CPCG01N5/025
Inventor 王北明龚俊瑞严高剑柴将红张超余良钟梁勇坤
Owner GUANGDONG SHUNFENG PHARMA
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