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Bacterium restraining gelatin and preparation method thereof

A gel and gel matrix technology, applied in antibacterial, antifungal, pharmaceutical formulations, etc., can solve the problems of patients with large side effects and poor antibacterial properties, reduce itching sensation, ensure transparency, and prevent skin drying effect

Inactive Publication Date: 2019-06-04
四川巴地凯尔生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation of the antibacterial gel can solve the problems of poor antibacterial performance and large side effects on patients in current antibacterial products, and can meet the needs of patients

Method used

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  • Bacterium restraining gelatin and preparation method thereof
  • Bacterium restraining gelatin and preparation method thereof
  • Bacterium restraining gelatin and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] An antibacterial gel, comprising the following raw materials in mass percentage: carbomer 0.60%; glycerin 1.0%; propylene glycol: 0.6%; borneol: 0.01%; triclosan: 0.25%; ethanol 0.5%; peppermint oil 0.05%; Bird's nest extract 0.5%; safflower extract 0.1%; ginseng extract 0.2%; dendrobium extract 0.2%; triethanolamine 0.35%;

[0037] The preparation method of above-mentioned antibacterial gel comprises the following steps:

[0038] 1) Weigh each component according to the specified mass percentage;

[0039]2) For the preparation of the gel matrix: dissolve the carbomer into pure water in proportion, leave it overnight (12h), and wait for its swelling to be complete, that is, the corresponding gel matrix is ​​prepared;

[0040] 3) Add glycerin and propylene glycol to the gel matrix and stir well, then add borneol and peppermint oil solution to it, add bird's nest extract, ginseng extract, safflower extract, dendrobium extract and stir well, and finally add trichloro raw...

Embodiment 2

[0043] An antibacterial gel, comprising the following raw materials in mass percentage: 0.60% carbomer; 1.0% glycerin; 0.6% propylene glycol; 0.01% borneol; 0.20% triclosan; 0.5% ethanol; 0.05% peppermint oil; 0.5%; 0.1% of safflower extract; 0.2% of ginseng extract; 0.2% of dendrobium extract; 0.35% of triethanolamine;

[0044] The preparation method of the antibacterial gel in this embodiment is the same as in Example 1, wherein the pH value of the antibacterial gel is adjusted to 5.8 by using triethanolamine.

Embodiment 3

[0046] An antibacterial gel, comprising the following raw materials in mass percentage: 0.60% carbomer; 1.0% glycerin; 0.6% propylene glycol; 0.01% borneol; 0.30% triclosan; 0.5% ethanol; 0.05% peppermint oil; 0.5%; 0.1% of safflower extract; 0.2% of ginseng extract; 0.2% of dendrobium extract; 0.35% of triethanolamine;

[0047] The preparation method of the antibacterial gel of this embodiment is the same as in Example 1, wherein the pH value of the antibacterial gel is adjusted to 5.8 by using triethanolamine.

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Abstract

The invention belongs to the field of medicine gelatin, and particularly relates to bacterium restraining gelatin and a preparation method thereof. The bacterium restraining gelatin comprises the following raw materials of 0.3-1.0% of carbomer, 0.5-3.0% of glycerine, 0.1-3.0% of propylene glycol, 0.01-1.0% of borneol, 0.1-0.5% of triclosan, 0.1-1.0% of ethanol, 0.01-1.0% of peppermint oil, 0.1-1.0% of an edible bird's nest extract, 0.1-1.0% of a safflower extract, 0.1-1.0% of a ginseng extract, 0.1-1.0% of a herba dendrobii extract, 0.1-1.0% of triethanolamine and the balance pure water. The bacterium restraining gelatin is prepared through a reasonable formula; various bacterium restraining active components are in combined use, so that the bacterium restraining gelatin obtains notable synergistic reactions in the respect of restraining bacteria, and can dispel pathogenic bacteria at affected parts, the pruritic feeling is alleviated and even eliminated, and the resistance capacity and the immune capacity of diseased regions to the pathogenic bacteria can be reinforced.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical gel preparation, in particular to an antibacterial gel and a preparation method thereof. technical background [0002] Skin disease is a common multiple disease with a high incidence rate, which has seriously affected people's daily life and work. There are many kinds of skin diseases, the etiology is complicated, and it is difficult to cure them, which brings different degrees of distress to patients. [0003] Both skin infections and skin lesions can cause skin diseases, and skin diseases caused by skin infections are more common. Skin infections are mainly caused by bacteria or fungi, such as Staphylococcus aureus, Escherichia coli, and Candida albicans. Therefore, the clinical treatment of skin diseases caused by skin infection generally adopts disinfection and antibacterial treatment methods. The existing antiseptic and antiseptic skin medicines mainly contain antiseptic and antisep...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61K9/06A61K47/10A61P31/04A61P31/10A61P31/02A61P17/00A61P17/04A61K31/045A61K31/085A61K35/57
Inventor 赵涛杨放杨垠杨昭武
Owner 四川巴地凯尔生物医药科技有限公司
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