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Dendrobium nobile extract with high fidelity and clarity and preparation method thereof

A dendrobium extract and extract technology, applied in the field of plant extracts and their preparation, can solve the problems of high production cost, adverse effects, complicated process, etc., and achieve the goal of reducing production energy consumption, good stability, and high content of active ingredients Effect

Pending Publication Date: 2019-05-17
SHANGHAI NOVANAT BIORESOURCES CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The introduced solvent needs to be re-separated, the process is complicated, and the residue may have adverse effects on the human body, which is not environmentally friendly and the production cost is high

Method used

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  • Dendrobium nobile extract with high fidelity and clarity and preparation method thereof
  • Dendrobium nobile extract with high fidelity and clarity and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Grind the dried Dendrobium officinale (commercially available) raw material and pass it through a 40-mesh sieve; take 5 kg of the crushed and sieved raw material, add 400 L of distilled water to soak for 20 min, and homogenize for 7 min at 25 MPa and 50 °C in a homogenizer. Pipeline transferred to the extraction tank at room temperature 20 ° C and stirred for 6 hours. The material is separated from the slag and liquid with a sedimentation centrifuge (2000r / min), and the residue is further extracted with 100L of boiling water for 1 hour, cooled, and centrifuged with a sedimentation centrifuge. Combine the supernatants from the two centrifuges and pass them through a centrifuge (12000r / min). The outlet tube of the centrifuge is tied with a 200-mesh filter bag. After passing through the alcohol precipitation tank, cool to below 60°C, pass through reverse osmosis membrane (8040 membrane) to concentrate, and after concentration, wash with 10L water for 3 times. Combine the ...

example 1

[0037] Example 1 Dendrobium officinale extract sample viscosity assay method:

[0038] Check with a rotational viscometer. The final sample was prepared as a 2.5 mg / ml solution, the rotational speed was 60 r / s, the rotor was No. 2, and the viscosity was 2.05 Pa·s.

[0039] The assay method of embodiment 1 Dendrobium officinale extract product turbidity, light transmittance:

[0040] Turbidity with a nephelometer. The light transmittance was measured by ultraviolet detection at 680nm. The lower the turbidity, the higher the light transmittance, indicating the better the clarity.

[0041] Among them, the tracking data on the clarification process is as follows:

[0042] sample solution

[0043] The above results showed that each clarification step can improve the clarification of Dendrobium officinale.

Embodiment 2

[0054] Grind the dried dendrobium dendrobium raw material and pass it through a 20-mesh sieve; take 10 kg of crushed and sieved raw material, add 500 L of distilled water, soak for 20 min, and homogenize for 10 min at a homogenizer of 35 MPa and 55 °C. Pipeline transfer to extraction tank at room temperature 20°C and stir for 12h. Use a sedimentation centrifuge (model PC-450) to separate the residue from the material, add 300L boiling water to extract the residue for 1 hour, cool it, and centrifuge it with a sedimentation centrifuge. Combine the centrifuged supernatants from the two times, and pass through a tube centrifuge (12000r / min). The outlet tube of the tube centrifuge is tied with a 300-mesh filter bag, and the supernatant is sterilized by UHT after filtering the bag. After passing through the alcohol precipitation tank, cool to below 60°C, pass through the RO membrane to concentrate, and after concentration, wash with 50L water for 3 times. Combine the concentrated s...

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Abstract

The invention provides a dendrobium nobile extract with high fidelity and clarity; provided is the dendrobium nobile extract with high fidelity and clarity. The content of polysaccharides in the extract is more than or equal to 50%, the viscosity of a 2.5 mg / ml solution is more than or equal to 1.8 Pa*s, and the turbidity NTU of the 2.5 mg / ml solution is less than or equal to 100. The invention also provides a preparation method of the dendrobium nobile extract with high fidelity and clarity, wherein the preparation method includes the steps: dissolving dendrobium nobile in distilled water, carrying out high-pressure homogeneous extraction of raw materials, carrying out combined use of sedimentation and tube separation centrifugal machines and plate-frame filtration, carrying out graded impurity removal, adopting a dendrobium nobile solution sterilized by UHT, concentrating the solution by a low-temperature RO film, carrying out vacuum drying and the like. The obtained dendrobium nobile extract has high polysaccharide content and good stability, and retains the content of effective ingredients to the greatest extent. The hidden danger of microorganisms exceeding the standard is eliminated. At the same time, the production energy consumption is greatly reduced and the cost is saved. The preparation method is simple and feasible, is suitable for industrial production, and has great application value.

Description

technical field [0001] The invention relates to a plant extract and a preparation method thereof, in particular to a high-fidelity, high-clarity dendrobium extract and a preparation method thereof. Background technique [0002] Dendrobium is an herbaceous plant belonging to the family Orchidaceae, which is an important and commonly used traditional Chinese medicinal material. Dendrobium candidum is rich in varieties, among which Dendrobium candidum is the most precious. It has the effects of nourishing yin and promoting body fluid, moistening throat and protecting throat, tonifying kidney and strengthening strength, and is known as "gold in medicine". Modern pharmacological and clinical studies have proved that Dendrobium officinale has anti-tumor, anti-aging, lowering blood sugar and improving immunity effects. The active substances of Dendrobium are mainly polysaccharide compounds, and their content is relatively high. In addition, Dendrobium officinale is also rich in am...

Claims

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Application Information

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IPC IPC(8): A61K36/8984
Inventor 周慧吉汤健俭殷梦龙
Owner SHANGHAI NOVANAT BIORESOURCES CO LTD
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